Gene Card
Best human hits
PLG; ROR1; ROR2
Species
Unique Gene ID
Phmamm.g00006498
Gene Model ID
Phmamm.CG.MTP2014.S273.g06498
Location
S273:686..18024
Transcript Models and Sequences
Phmamm.CG.MTP2014.S273.g06498.01.t
Phmamm.CG.MTP2014.S273.g06498.02.t
AHC0AAA143YF03
Plate: Plate_143_F03
AHC0AAA234YM13
Plate: Plate_234_M13
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Kringle | SMART | Kringle |
Frizzled_dom | Pfam | Frizzled domain |
Kringle | CDD | Kringle |
Kringle-like | SUPERFAMILY | Kringle-like fold |
Frizzled_dom | ProSiteProfiles | Frizzled domain |
Ig_sub | SMART | Immunoglobulin subtype |
Ig_I-set | Pfam | Immunoglobulin I-set |
Kringle_sf | Gene3D | Kringle superfamily |
Ig-like_fold | Gene3D | Immunoglobulin-like fold |
Ig_sub2 | SMART | Immunoglobulin subtype 2 |
Kringle | Pfam | Kringle |
Ser-Thr/Tyr_kinase_cat_dom | Pfam | Serine-threonine/tyrosine-protein kinase, catalytic domain |
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
Kringle | ProSiteProfiles | Kringle |
Ig-like_dom_sf | SUPERFAMILY | Immunoglobulin-like domain superfamily |
Ig-like_dom | ProSiteProfiles | Immunoglobulin-like domain |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Kringle_CS | ProSitePatterns | Kringle, conserved site |
Frizzled_dom_sf | Gene3D | Frizzled cysteine-rich domain superfamily |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
endopeptidase activity | Blast | molecular function |
serine-type endopeptidase activity | Blast | molecular function |
protein kinase activity | Orthology | molecular function |
receptor binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
extracellular region | Blast | cellular component |
extracellular space | Blast | cellular component |
cytoplasm | Orthology | cellular component |
microtubule | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
integral component of plasma membrane | Orthology | cellular component |
protein phosphorylation | Orthology | biological process |
signal transduction | Orthology | biological process |
multicellular organism development | Orthology | biological process |
sensory perception of sound | Orthology | biological process |
peptidase activity | Blast | molecular function |
serine-type peptidase activity | Blast | molecular function |
negative regulation of cell proliferation | Orthology | biological process |
cell surface | Orthology | cellular component |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
transferase activity | Orthology | molecular function |
hydrolase activity | Blast | molecular function |
enzyme binding | Blast | molecular function |
kinase binding | Blast | molecular function |
cell differentiation | Orthology | biological process |
axon | Orthology | cellular component |
cell projection | Orthology | cellular component |
neuronal cell body | Orthology | cellular component |
positive regulation of transcription, DNA-templated | Orthology | biological process |
metal ion binding | Orthology | molecular function |
regulation of canonical Wnt signaling pathway | Orthology | biological process |
extracellular exosome | Blast | cellular component |
negative regulation of canonical Wnt signaling pathway | Orthology | biological process |
positive regulation of canonical Wnt signaling pathway | Orthology | biological process |
system development | Orthology | biological process |
animal organ development | Orthology | biological process |
anatomical structure morphogenesis | Orthology | biological process |
cytoskeletal part | Orthology | cellular component |
anatomical structure formation involved in morphogenesis | Orthology | biological process |
transmembrane signaling receptor activity | Orthology | molecular function |
cell surface receptor signaling pathway | Orthology | biological process |
cell-cell signaling | Orthology | biological process |
cellular response to stress | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
cell development | Orthology | biological process |
neurogenesis | Orthology | biological process |
central nervous system development | Orthology | biological process |
cell migration | Orthology | biological process |
regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
reproductive process | Orthology | biological process |
whole membrane | Orthology | cellular component |
intracellular organelle part | Orthology | cellular component |
cytoplasmic vesicle | Orthology | cellular component |
bounding membrane of organelle | Orthology | cellular component |
transcription factor activity, sequence-specific DNA binding | Orthology | molecular function |
positive regulation of signal transduction | Orthology | biological process |
macromolecular complex | Orthology | cellular component |
positive regulation of catalytic activity | Orthology | biological process |
protein serine/threonine kinase activity | Orthology | molecular function |
cell projection part | Orthology | cellular component |
synapse part | Orthology | cellular component |
chemical synaptic transmission | Orthology | biological process |
signaling receptor activity | Orthology | molecular function |
immune system process | Orthology | biological process |
endomembrane system | Blast | cellular component |
intracellular organelle lumen | Blast | cellular component |
plasma membrane part | Blast | cellular component |
macromolecular complex binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 294 | 4.09e-89 |
stress fiber | Hs | cellular component | 288 | 5.70e-87 |
endopeptidase activity | Hs | molecular function | 63.5 | 1.75e-10 |
serine-type endopeptidase activity | Hs | molecular function | 63.5 | 1.75e-10 |
protein kinase activity | Hs | molecular function | 294 | 4.09e-89 |
protein tyrosine kinase activity | Hs | molecular function | 294 | 4.09e-89 |
transmembrane receptor protein tyrosine kinase activity | Hs | molecular function | 294 | 4.09e-89 |
receptor binding | Hs | molecular function | 63.5 | 1.75e-10 |
frizzled binding | Hs | molecular function | 294 | 4.09e-89 |
protein binding | Hs | molecular function | 294 | 4.09e-89 |
ATP binding | Hs | molecular function | 294 | 4.09e-89 |
extracellular region | Hs | cellular component | 63.5 | 1.75e-10 |
extracellular space | Hs | cellular component | 63.5 | 1.75e-10 |
cytoplasm | Hs | cellular component | 294 | 4.09e-89 |
microtubule | Hs | cellular component | 294 | 4.09e-89 |
plasma membrane | Hs | cellular component | 294 | 4.09e-89 |
integral component of plasma membrane | Hs | cellular component | 294 | 4.09e-89 |
peptidase activity | Hs | molecular function | 63.5 | 1.75e-10 |
serine-type peptidase activity | Hs | molecular function | 63.5 | 1.75e-10 |
cell surface | Hs | cellular component | 294 | 4.09e-89 |
membrane | Hs | cellular component | 294 | 4.09e-89 |
integral component of membrane | Hs | cellular component | 294 | 4.09e-89 |
kinase activity | Hs | molecular function | 294 | 4.09e-89 |
transferase activity | Hs | molecular function | 294 | 4.09e-89 |
hydrolase activity | Hs | molecular function | 63.5 | 1.75e-10 |
Wnt-protein binding | Hs | molecular function | 294 | 4.09e-89 |
enzyme binding | Hs | molecular function | 63.5 | 1.75e-10 |
kinase binding | Hs | molecular function | 63.5 | 1.75e-10 |
protein domain specific binding | Hs | molecular function | 63.5 | 1.75e-10 |
axon | Hs | cellular component | 288 | 5.70e-87 |
dendrite | Hs | cellular component | 294 | 4.09e-89 |
clathrin-coated endocytic vesicle membrane | Hs | cellular component | 294 | 4.09e-89 |
platelet alpha granule lumen | Hs | cellular component | 63.5 | 1.75e-10 |
extrinsic component of external side of plasma membrane | Hs | cellular component | 63.5 | 1.75e-10 |
apolipoprotein binding | Hs | molecular function | 63.5 | 1.75e-10 |
Wnt-activated receptor activity | Hs | molecular function | 288 | 5.70e-87 |
cell projection | Hs | cellular component | 288 | 5.70e-87 |
neuronal cell body | Hs | cellular component | 294 | 4.09e-89 |
receptor complex | Hs | cellular component | 288 | 5.70e-87 |
axon terminus | Hs | cellular component | 288 | 5.70e-87 |
other organism cell membrane | Hs | cellular component | 63.5 | 1.75e-10 |
metal ion binding | Hs | molecular function | 294 | 4.09e-89 |
chaperone binding | Hs | molecular function | 63.5 | 1.75e-10 |
extracellular exosome | Hs | cellular component | 63.5 | 1.75e-10 |
blood microparticle | Hs | cellular component | 63.5 | 1.75e-10 |
proteasome core complex binding | Hs | molecular function | 63.5 | 1.75e-10 |
coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway | Hs | molecular function | 294 | 4.09e-89 |
protein antigen binding | Hs | molecular function | 63.5 | 1.75e-10 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 2.5E-9 |
protein binding | Gene3D | molecular function | 8.2E-26 |
ATP binding | ProSiteProfiles | molecular function | 10.973 |
protein phosphorylation | Pfam | biological process | 2.5E-9 |