Gene Card
Best human hits
SLC6A2; SLC6A3; SLC6A4
Species
Unique Gene ID
Phmamm.g00004422
Gene Model ID
Phmamm.CG.MTP2014.S158.g04422
Location
S158:181378..186930
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Na/ntran_symport | ProSiteProfiles | Sodium:neurotransmitter symporter |
Na/ntran_symport | Pfam | Sodium:neurotransmitter symporter |
Na/ntran_symport | PANTHER | Sodium:neurotransmitter symporter |
Na/ntran_symport | PRINTS | Sodium:neurotransmitter symporter |
Na/ntran_symport | ProSitePatterns | Sodium:neurotransmitter symporter |
SNS_sf | SUPERFAMILY | Sodium:neurotransmitter symporter superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
response to hypoxia | Orthology | biological process |
receptor binding | Blast | molecular function |
protein binding | Orthology | molecular function |
cytoplasm | Blast | cellular component |
endosome | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
integral component of plasma membrane | Orthology | cellular component |
chemical synaptic transmission | Orthology | biological process |
brain development | Orthology | biological process |
cell surface | Blast | cellular component |
response to organic substance | Orthology | biological process |
positive regulation of gene expression | Orthology | biological process |
endomembrane system | Orthology | cellular component |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
axon | Blast | cellular component |
protein homodimerization activity | Orthology | molecular function |
neuron projection | Orthology | cellular component |
neuronal cell body | Blast | cellular component |
membrane raft | Orthology | cellular component |
metal ion binding | Orthology | molecular function |
protein N-terminus binding | Blast | molecular function |
actin filament binding | Orthology | molecular function |
protein oligomerization | Orthology | biological process |
protein homooligomerization | Orthology | biological process |
transmembrane transport | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
sodium ion transport | Orthology | biological process |
organic substance transport | Orthology | biological process |
synapse part | Orthology | cellular component |
neuron part | Orthology | cellular component |
cation transport | Orthology | biological process |
nervous system process | Orthology | biological process |
intracellular organelle part | Orthology | cellular component |
whole membrane | Orthology | cellular component |
bounding membrane of organelle | Orthology | cellular component |
cytoskeletal protein binding | Orthology | molecular function |
enzyme binding | Orthology | molecular function |
cation binding | Orthology | molecular function |
heterocyclic compound binding | Orthology | molecular function |
organic cyclic compound binding | Orthology | molecular function |
response to lipid | Orthology | biological process |
cellular biosynthetic process | Orthology | biological process |
sexual reproduction | Orthology | biological process |
multicellular organismal reproductive process | Orthology | biological process |
cell development | Orthology | biological process |
neuron differentiation | Orthology | biological process |
cell cycle | Orthology | biological process |
developmental process | Orthology | biological process |
anatomical structure morphogenesis | Orthology | biological process |
binding | Blast | molecular function |
plasma membrane region | Blast | cellular component |
macromolecular complex | Blast | cellular component |
tubulin binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
response to hypoxia | Hs | biological process |
neurotransmitter:sodium symporter activity | Hs | molecular function |
dopamine:sodium symporter activity | Hs | molecular function |
serotonin:sodium symporter activity | Hs | molecular function |
protein binding | Hs | molecular function |
endosome | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
integral component of plasma membrane | Hs | cellular component |
neurotransmitter transport | Hs | biological process |
serotonin transport | Hs | biological process |
brain development | Hs | biological process |
response to nutrient | Hs | biological process |
memory | Hs | biological process |
circadian rhythm | Hs | biological process |
monoamine transmembrane transporter activity | Hs | molecular function |
response to toxic substance | Hs | biological process |
endosome membrane | Hs | cellular component |
response to organic substance | Hs | biological process |
positive regulation of gene expression | Hs | biological process |
endomembrane system | Hs | cellular component |
serotonin transmembrane transporter activity | Hs | molecular function |
symporter activity | Hs | molecular function |
monoamine transport | Hs | biological process |
membrane | Hs | cellular component |
integral component of membrane | Hs | cellular component |
myosin binding | Hs | molecular function |
syntaxin-1 binding | Hs | molecular function |
Rab GTPase binding | Hs | molecular function |
cocaine binding | Hs | molecular function |
response to estradiol | Hs | biological process |
social behavior | Hs | biological process |
neurotransmitter biosynthetic process | Hs | biological process |
vasoconstriction | Hs | biological process |
response to drug | Hs | biological process |
sperm ejaculation | Hs | biological process |
protein homodimerization activity | Hs | molecular function |
neuron projection | Hs | cellular component |
membrane raft | Hs | cellular component |
negative regulation of neuron differentiation | Hs | biological process |
positive regulation of cell cycle | Hs | biological process |
negative regulation of organ growth | Hs | biological process |
metal ion binding | Hs | molecular function |
brain morphogenesis | Hs | biological process |
nitric-oxide synthase binding | Hs | molecular function |
actin filament binding | Hs | molecular function |
protein oligomerization | Hs | biological process |
protein homooligomerization | Hs | biological process |
dopamine uptake involved in synaptic transmission | Hs | biological process |
serotonin uptake | Hs | biological process |
transmembrane transport | Hs | biological process |
cellular response to retinoic acid | Hs | biological process |
cellular response to organic substance | Hs | biological process |
cellular response to cGMP | Hs | biological process |
presynapse | Hs | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
protease binding | Hs | molecular function | 413 | 1.09e-139 |
receptor binding | Hs | molecular function | 413 | 1.09e-139 |
neurotransmitter:sodium symporter activity | Hs | molecular function | 487 | 1.12e-168 |
dopamine transmembrane transporter activity | Hs | molecular function | 413 | 1.09e-139 |
dopamine:sodium symporter activity | Hs | molecular function | 487 | 1.12e-168 |
norepinephrine transmembrane transporter activity | Hs | molecular function | 451 | 1.47e-154 |
norepinephrine:sodium symporter activity | Hs | molecular function | 451 | 1.47e-154 |
serotonin:sodium symporter activity | Hs | molecular function | 487 | 1.12e-168 |
protein binding | Hs | molecular function | 487 | 1.12e-168 |
cytoplasm | Hs | cellular component | 413 | 1.09e-139 |
endosome | Hs | cellular component | 487 | 1.12e-168 |
cytosol | Hs | cellular component | 487 | 1.12e-168 |
plasma membrane | Hs | cellular component | 487 | 1.12e-168 |
integral component of plasma membrane | Hs | cellular component | 487 | 1.12e-168 |
drug binding | Hs | molecular function | 413 | 1.09e-139 |
monoamine transmembrane transporter activity | Hs | molecular function | 487 | 1.12e-168 |
cell surface | Hs | cellular component | 451 | 1.47e-154 |
endosome membrane | Hs | cellular component | 487 | 1.12e-168 |
endomembrane system | Hs | cellular component | 487 | 1.12e-168 |
serotonin transmembrane transporter activity | Hs | molecular function | 487 | 1.12e-168 |
symporter activity | Hs | molecular function | 487 | 1.12e-168 |
membrane | Hs | cellular component | 487 | 1.12e-168 |
integral component of membrane | Hs | cellular component | 487 | 1.12e-168 |
flotillin complex | Hs | cellular component | 413 | 1.09e-139 |
myosin binding | Hs | molecular function | 487 | 1.12e-168 |
syntaxin-1 binding | Hs | molecular function | 487 | 1.12e-168 |
Rab GTPase binding | Hs | molecular function | 487 | 1.12e-168 |
cocaine binding | Hs | molecular function | 487 | 1.12e-168 |
axon | Hs | cellular component | 413 | 1.09e-139 |
dopamine binding | Hs | molecular function | 413 | 1.09e-139 |
protein homodimerization activity | Hs | molecular function | 487 | 1.12e-168 |
neuron projection | Hs | cellular component | 487 | 1.12e-168 |
alpha-tubulin binding | Hs | molecular function | 451 | 1.47e-154 |
neuronal cell body | Hs | cellular component | 413 | 1.09e-139 |
membrane raft | Hs | cellular component | 487 | 1.12e-168 |
metal ion binding | Hs | molecular function | 487 | 1.12e-168 |
protein N-terminus binding | Hs | molecular function | 413 | 1.09e-139 |
beta-tubulin binding | Hs | molecular function | 451 | 1.47e-154 |
nitric-oxide synthase binding | Hs | molecular function | 487 | 1.12e-168 |
actin filament binding | Hs | molecular function | 487 | 1.12e-168 |
protein phosphatase 2A binding | Hs | molecular function | 413 | 1.09e-139 |
presynapse | Hs | cellular component | 487 | 1.12e-168 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
neurotransmitter:sodium symporter activity | PANTHER | molecular function | 5.0E-174 |
neurotransmitter transport | PANTHER | biological process | 5.0E-174 |
integral component of membrane | PANTHER | cellular component | 5.0E-174 |