IPR Term	Analysis	Definition
Ig_sub	SMART	Immunoglobulin subtype
Kringle-like	SUPERFAMILY	Kringle-like fold
Kringle	ProSiteProfiles	Kringle
Ig_I-set	Pfam	Immunoglobulin I-set
Frizzled_dom_sf	Gene3D	Frizzled cysteine-rich domain superfamily
Ig-like_dom	ProSiteProfiles	Immunoglobulin-like domain
Kringle_sf	Gene3D	Kringle superfamily
Tyr_kinase_cat_dom	SMART	Tyrosine-protein kinase, catalytic domain
Ig_sub2	SMART	Immunoglobulin subtype 2
Frizzled_dom	ProSiteProfiles	Frizzled domain
Ser-Thr/Tyr_kinase_cat_dom	Pfam	Serine-threonine/tyrosine-protein kinase, catalytic domain
Kringle_CS	ProSitePatterns	Kringle, conserved site
Prot_kinase_dom	ProSiteProfiles	Protein kinase domain
Ser-Thr/Tyr_kinase_cat_dom	PRINTS	Serine-threonine/tyrosine-protein kinase, catalytic domain
Kinase-like_dom_sf	SUPERFAMILY	Protein kinase-like domain superfamily
Kringle	SMART	Kringle
Frizzled_dom	Pfam	Frizzled domain
Ig-like_dom_sf	SUPERFAMILY	Immunoglobulin-like domain superfamily
Ig-like_fold	Gene3D	Immunoglobulin-like fold
Kringle	Pfam	Kringle

GO Term	Annotation Origin	Type
nucleotide binding	Orthology	molecular function
protein kinase activity	Orthology	molecular function
protein binding	Orthology	molecular function
ATP binding	Orthology	molecular function
cytoplasm	Orthology	cellular component
microtubule	Orthology	cellular component
plasma membrane	Orthology	cellular component
integral component of plasma membrane	Orthology	cellular component
protein phosphorylation	Orthology	biological process
signal transduction	Orthology	biological process
multicellular organism development	Orthology	biological process
sensory perception of sound	Orthology	biological process
negative regulation of cell proliferation	Orthology	biological process
cell surface	Orthology	cellular component
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
kinase activity	Orthology	molecular function
phosphorylation	Orthology	biological process
transferase activity	Orthology	molecular function
cell junction	Blast	cellular component
cell differentiation	Orthology	biological process
axon	Orthology	cellular component
cell projection	Orthology	cellular component
neuronal cell body	Orthology	cellular component
synapse	Blast	cellular component
postsynaptic membrane	Blast	cellular component
positive regulation of transcription, DNA-templated	Orthology	biological process
metal ion binding	Orthology	molecular function
regulation of canonical Wnt signaling pathway	Orthology	biological process
negative regulation of canonical Wnt signaling pathway	Orthology	biological process
positive regulation of canonical Wnt signaling pathway	Orthology	biological process
system development	Orthology	biological process
animal organ development	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
cytoskeletal part	Orthology	cellular component
anatomical structure formation involved in morphogenesis	Orthology	biological process
transmembrane signaling receptor activity	Orthology	molecular function
receptor binding	Orthology	molecular function
cell surface receptor signaling pathway	Orthology	biological process
cell-cell signaling	Orthology	biological process
cellular response to stress	Orthology	biological process
intracellular signal transduction	Orthology	biological process
cell development	Orthology	biological process
neurogenesis	Orthology	biological process
central nervous system development	Orthology	biological process
cell migration	Orthology	biological process
regulation of transcription from RNA polymerase II promoter	Orthology	biological process
cellular response to organic substance	Orthology	biological process
reproductive process	Orthology	biological process
whole membrane	Orthology	cellular component
intracellular organelle part	Orthology	cellular component
cytoplasmic vesicle	Orthology	cellular component
bounding membrane of organelle	Orthology	cellular component
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
positive regulation of signal transduction	Orthology	biological process
macromolecular complex	Orthology	cellular component
positive regulation of catalytic activity	Orthology	biological process
protein serine/threonine kinase activity	Orthology	molecular function
cell projection part	Orthology	cellular component
synapse part	Orthology	cellular component
chemical synaptic transmission	Orthology	biological process
signaling receptor activity	Orthology	molecular function
immune system process	Orthology	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
nucleotide binding	Hs	molecular function
skeletal system development	Hs	biological process
cartilage condensation	Hs	biological process
stress fiber	Hs	cellular component
somitogenesis	Hs	biological process
protein kinase activity	Hs	molecular function
protein tyrosine kinase activity	Hs	molecular function
transmembrane receptor protein tyrosine kinase activity	Hs	molecular function
frizzled binding	Hs	molecular function
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
cytoplasm	Hs	cellular component
microtubule	Hs	cellular component
plasma membrane	Hs	cellular component
integral component of plasma membrane	Hs	cellular component
protein phosphorylation	Hs	biological process
signal transduction	Hs	biological process
transmembrane receptor protein tyrosine kinase signaling pathway	Hs	biological process
Wnt signaling pathway, calcium modulating pathway	Hs	biological process
smoothened signaling pathway	Hs	biological process
JNK cascade	Hs	biological process
multicellular organism development	Hs	biological process
sensory perception of sound	Hs	biological process
negative regulation of cell proliferation	Hs	biological process
cell surface	Hs	cellular component
astrocyte development	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
Wnt signaling pathway	Hs	biological process
kinase activity	Hs	molecular function
phosphorylation	Hs	biological process
transferase activity	Hs	molecular function
Wnt-protein binding	Hs	molecular function
peptidyl-tyrosine phosphorylation	Hs	biological process
cell differentiation	Hs	biological process
bone mineralization	Hs	biological process
positive regulation of cell migration	Hs	biological process
axon	Hs	cellular component
dendrite	Hs	cellular component
BMP signaling pathway	Hs	biological process
embryonic genitalia morphogenesis	Hs	biological process
male genitalia development	Hs	biological process
clathrin-coated endocytic vesicle membrane	Hs	cellular component
inner ear morphogenesis	Hs	biological process
Wnt-activated receptor activity	Hs	molecular function
cell projection	Hs	cellular component
neuronal cell body	Hs	cellular component
positive regulation of I-kappaB kinase/NF-kappaB signaling	Hs	biological process
receptor complex	Hs	cellular component
positive regulation of JUN kinase activity	Hs	biological process
axon terminus	Hs	cellular component
cell fate commitment	Hs	biological process
positive regulation of transcription, DNA-templated	Hs	biological process
metal ion binding	Hs	molecular function
inner ear development	Hs	biological process
positive regulation of NF-kappaB transcription factor activity	Hs	biological process
positive regulation of synaptic transmission, glutamatergic	Hs	biological process
Wnt signaling pathway, planar cell polarity pathway	Hs	biological process
SMAD protein signal transduction	Hs	biological process
regulation of canonical Wnt signaling pathway	Hs	biological process
negative regulation of canonical Wnt signaling pathway	Hs	biological process
positive regulation of canonical Wnt signaling pathway	Hs	biological process
coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway	Hs	molecular function
macrophage migration	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	332	7.10e-101
stress fiber	Hs	cellular component	332	7.10e-101
protein kinase activity	Hs	molecular function	332	7.10e-101
protein tyrosine kinase activity	Hs	molecular function	329	7.67e-100
transmembrane receptor protein tyrosine kinase activity	Hs	molecular function	332	7.10e-101
frizzled binding	Hs	molecular function	329	7.67e-100
protein binding	Hs	molecular function	332	7.10e-101
ATP binding	Hs	molecular function	332	7.10e-101
cytoplasm	Hs	cellular component	332	7.10e-101
microtubule	Hs	cellular component	329	7.67e-100
plasma membrane	Hs	cellular component	332	7.10e-101
integral component of plasma membrane	Hs	cellular component	332	7.10e-101
cell surface	Hs	cellular component	332	7.10e-101
membrane	Hs	cellular component	332	7.10e-101
integral component of membrane	Hs	cellular component	332	7.10e-101
kinase activity	Hs	molecular function	332	7.10e-101
transferase activity	Hs	molecular function	332	7.10e-101
Wnt-protein binding	Hs	molecular function	332	7.10e-101
cell junction	Hs	cellular component	140	2.02e-34
axon	Hs	cellular component	332	7.10e-101
dendrite	Hs	cellular component	329	7.67e-100
clathrin-coated endocytic vesicle membrane	Hs	cellular component	329	7.67e-100
neuromuscular junction	Hs	cellular component	140	2.02e-34
Wnt-activated receptor activity	Hs	molecular function	332	7.10e-101
cell projection	Hs	cellular component	332	7.10e-101
neuronal cell body	Hs	cellular component	329	7.67e-100
receptor complex	Hs	cellular component	332	7.10e-101
axon terminus	Hs	cellular component	332	7.10e-101
synapse	Hs	cellular component	140	2.02e-34
postsynaptic membrane	Hs	cellular component	140	2.02e-34
metal ion binding	Hs	molecular function	329	7.67e-100
coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway	Hs	molecular function	332	7.10e-101

GO Term	Analysis	Type	e-value
protein kinase activity	Pfam	molecular function	2.7E-50
protein tyrosine kinase activity	SMART	molecular function	1.5E-44
protein binding	Gene3D	molecular function	1.3E-23
ATP binding	ProSiteProfiles	molecular function	25.757
protein phosphorylation	Pfam	biological process	2.7E-50