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Gene Card

Best human hits

IGF1R; INSR; INSRR

Species

P.fumigata

Unique Gene ID

Phfumi.g00002332

Gene Model ID

Phfumi.CG.MTP2014.S570.g02332

Location

S570:19854..25915

Transcript Models and Sequences

  Phfumi.CG.MTP2014.S570.g02332.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
Ser-Thr/Tyr_kinase_cat_dom PRINTS Serine-threonine/tyrosine-protein kinase, catalytic domain
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain
Tyr_kinase_cat_dom SMART Tyrosine-protein kinase, catalytic domain
Tyr_kinase_AS ProSitePatterns Tyrosine-protein kinase, active site
Tyr_kinase_rcpt_2_CS ProSitePatterns Tyrosine-protein kinase, receptor class II, conserved site
Prot_kinase_dom ProSiteProfiles Protein kinase domain

GOSlim

37 results

GO Term Annotation Origin Type
nucleotide binding Blast molecular function
protein kinase activity Blast molecular function
protein binding Blast molecular function
ATP binding Blast molecular function
GTP binding Blast molecular function
intracellular Blast cellular component
nuclear envelope Blast cellular component
plasma membrane Blast cellular component
integral component of plasma membrane Blast cellular component
protein phosphorylation InterProScan biological process
membrane Blast cellular component
integral component of membrane Blast cellular component
kinase activity Blast molecular function
transferase activity Blast molecular function
nuclear lumen Blast cellular component
identical protein binding Blast molecular function
intracellular membrane-bounded organelle Blast cellular component
macromolecular complex binding Blast molecular function
extracellular exosome Blast cellular component
binding Blast molecular function
transmembrane signaling receptor activity Blast molecular function
cell surface receptor signaling pathway Blast biological process
cellular response to organic substance Blast biological process
receptor binding Blast molecular function
macromolecular complex Blast cellular component
membrane raft Blast cellular component
plasma membrane region Blast cellular component
plasma membrane part Blast cellular component
cell surface Blast cellular component
intracellular organelle part Blast cellular component
whole membrane Blast cellular component
endosome Blast cellular component
bounding membrane of organelle Blast cellular component
cell projection membrane Blast cellular component
cell leading edge Blast cellular component
neuron projection Blast cellular component
neuronal cell body Blast cellular component

GO (Orthology)

No result

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type

GO (Blast)

43 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 263 1.66e-80
amyloid-beta binding Hs molecular function 263 1.66e-80
protein kinase activity Hs molecular function 263 1.66e-80
protein tyrosine kinase activity Hs molecular function 263 1.66e-80
transmembrane receptor protein tyrosine kinase activity Hs molecular function 263 1.66e-80
signal transducer, downstream of receptor, with protein tyrosine kinase activity Hs molecular function 263 1.66e-80
insulin-activated receptor activity Hs molecular function 263 1.66e-80
insulin-like growth factor-activated receptor activity Hs molecular function 259 2.90e-79
insulin receptor binding Hs molecular function 259 2.90e-79
insulin-like growth factor receptor binding Hs molecular function 263 1.66e-80
protein binding Hs molecular function 263 1.66e-80
insulin-like growth factor binding Hs molecular function 259 2.90e-79
ATP binding Hs molecular function 263 1.66e-80
GTP binding Hs molecular function 263 1.66e-80
intracellular Hs cellular component 263 1.66e-80
nuclear envelope Hs cellular component 263 1.66e-80
plasma membrane Hs cellular component 263 1.66e-80
integral component of plasma membrane Hs cellular component 263 1.66e-80
insulin receptor complex Hs cellular component 263 1.66e-80
caveola Hs cellular component 263 1.66e-80
external side of plasma membrane Hs cellular component 263 1.66e-80
endosome membrane Hs cellular component 263 1.66e-80
membrane Hs cellular component 263 1.66e-80
integral component of membrane Hs cellular component 263 1.66e-80
kinase activity Hs molecular function 263 1.66e-80
transferase activity Hs molecular function 263 1.66e-80
protein domain specific binding Hs molecular function 263 1.66e-80
nuclear lumen Hs cellular component 263 1.66e-80
insulin-like growth factor I binding Hs molecular function 263 1.66e-80
insulin-like growth factor II binding Hs molecular function 263 1.66e-80
dendrite membrane Hs cellular component 263 1.66e-80
neuronal cell body membrane Hs cellular component 263 1.66e-80
alphav-beta3 integrin-IGF-1-IGF1R complex Hs cellular component 259 2.90e-79
identical protein binding Hs molecular function 259 2.90e-79
intracellular membrane-bounded organelle Hs cellular component 259 2.90e-79
receptor complex Hs cellular component 263 1.66e-80
phosphatidylinositol 3-kinase binding Hs molecular function 263 1.66e-80
insulin binding Hs molecular function 263 1.66e-80
insulin receptor substrate binding Hs molecular function 263 1.66e-80
macromolecular complex binding Hs molecular function 263 1.66e-80
PTB domain binding Hs molecular function 263 1.66e-80
extracellular exosome Hs cellular component 263 1.66e-80
amyloid-beta complex Hs cellular component 263 1.66e-80

GO (InterProScan)

7 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 7.1E-65
protein tyrosine kinase activity SMART molecular function 1.5E-45
transmembrane receptor protein tyrosine kinase activity ProSitePatterns molecular function
ATP binding ProSiteProfiles molecular function 25.234
protein phosphorylation Pfam biological process 7.1E-65
transmembrane receptor protein tyrosine kinase signaling pathway ProSitePatterns biological process
membrane ProSitePatterns cellular component

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