Gene Card
Best human hits
SQSTM1
Species
Unique Gene ID
Moocul.g00013457
Gene Model ID
Moocul.CG.ELv1_2.S114450.g13457
Location
S114450:24306..26789
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
5 results
| IPR Term | Analysis | Definition |
|---|---|---|
| UBA-like_sf | SUPERFAMILY | UBA-like superfamily |
| PB1_dom | SMART | PB1 domain |
| SQSTM_UBA | Pfam | Sequestosome-1, UBA domain |
| PB1_dom | ProSiteProfiles | PB1 domain |
| PB1_dom | Pfam | PB1 domain |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
66 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| negative regulation of transcription from RNA polymerase II promoter | Hs | biological process |
| pre-autophagosomal structure | Hs | cellular component |
| autophagy of mitochondrion | Hs | biological process |
| mitophagy | Hs | biological process |
| P-body | Hs | cellular component |
| positive regulation of protein phosphorylation | Hs | biological process |
| immune system process | Hs | biological process |
| response to ischemia | Hs | biological process |
| protein serine/threonine kinase activity | Hs | molecular function |
| protein kinase C binding | Hs | molecular function |
| protein binding | Hs | molecular function |
| nucleus | Hs | cellular component |
| nucleoplasm | Hs | cellular component |
| cytoplasm | Hs | cellular component |
| lysosome | Hs | cellular component |
| endosome | Hs | cellular component |
| late endosome | Hs | cellular component |
| autophagosome | Hs | cellular component |
| endoplasmic reticulum | Hs | cellular component |
| cytosol | Hs | cellular component |
| protein phosphorylation | Hs | biological process |
| ubiquitin-dependent protein catabolic process | Hs | biological process |
| autophagy | Hs | biological process |
| apoptotic process | Hs | biological process |
| endosome organization | Hs | biological process |
| protein localization | Hs | biological process |
| zinc ion binding | Hs | molecular function |
| regulation of mitochondrion organization | Hs | biological process |
| endosomal transport | Hs | biological process |
| inclusion body | Hs | cellular component |
| aggresome | Hs | cellular component |
| macroautophagy | Hs | biological process |
| PML body | Hs | cellular component |
| enzyme binding | Hs | molecular function |
| protein kinase binding | Hs | molecular function |
| sarcomere | Hs | cellular component |
| cell differentiation | Hs | biological process |
| receptor tyrosine kinase binding | Hs | molecular function |
| cytoplasmic vesicle | Hs | cellular component |
| ubiquitin protein ligase binding | Hs | molecular function |
| ionotropic glutamate receptor binding | Hs | molecular function |
| intracellular signal transduction | Hs | biological process |
| aggrephagy | Hs | biological process |
| SH2 domain binding | Hs | molecular function |
| identical protein binding | Hs | molecular function |
| protein homodimerization activity | Hs | molecular function |
| positive regulation of apoptotic process | Hs | biological process |
| negative regulation of apoptotic process | Hs | biological process |
| regulation of I-kappaB kinase/NF-kappaB signaling | Hs | biological process |
| ubiquitin binding | Hs | molecular function |
| intracellular membrane-bounded organelle | Hs | cellular component |
| negative regulation of growth of symbiont in host | Hs | biological process |
| amphisome | Hs | cellular component |
| autolysosome | Hs | cellular component |
| positive regulation of transcription from RNA polymerase II promoter | Hs | biological process |
| regulation of Ras protein signal transduction | Hs | biological process |
| metal ion binding | Hs | molecular function |
| protein heterooligomerization | Hs | biological process |
| regulation of protein complex stability | Hs | biological process |
| extracellular exosome | Hs | cellular component |
| interleukin-1-mediated signaling pathway | Hs | biological process |
| K63-linked polyubiquitin modification-dependent protein binding | Hs | molecular function |
| sperm midpiece | Hs | cellular component |
| Lewy body | Hs | cellular component |
| response to mitochondrial depolarisation | Hs | biological process |
| positive regulation of protein localization to plasma membrane | Hs | biological process |
GO (Blast)
37 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| pre-autophagosomal structure | Hs | cellular component | 70.1 | 3.59e-13 |
| P-body | Hs | cellular component | 70.1 | 3.59e-13 |
| protein serine/threonine kinase activity | Hs | molecular function | 70.1 | 3.59e-13 |
| protein kinase C binding | Hs | molecular function | 70.1 | 3.59e-13 |
| protein binding | Hs | molecular function | 70.1 | 3.59e-13 |
| nucleus | Hs | cellular component | 70.1 | 3.59e-13 |
| nucleoplasm | Hs | cellular component | 70.1 | 3.59e-13 |
| cytoplasm | Hs | cellular component | 70.1 | 3.59e-13 |
| lysosome | Hs | cellular component | 70.1 | 3.59e-13 |
| endosome | Hs | cellular component | 70.1 | 3.59e-13 |
| late endosome | Hs | cellular component | 70.1 | 3.59e-13 |
| autophagosome | Hs | cellular component | 70.1 | 3.59e-13 |
| endoplasmic reticulum | Hs | cellular component | 70.1 | 3.59e-13 |
| cytosol | Hs | cellular component | 70.1 | 3.59e-13 |
| zinc ion binding | Hs | molecular function | 70.1 | 3.59e-13 |
| inclusion body | Hs | cellular component | 70.1 | 3.59e-13 |
| aggresome | Hs | cellular component | 70.1 | 3.59e-13 |
| PML body | Hs | cellular component | 70.1 | 3.59e-13 |
| enzyme binding | Hs | molecular function | 70.1 | 3.59e-13 |
| protein kinase binding | Hs | molecular function | 70.1 | 3.59e-13 |
| sarcomere | Hs | cellular component | 70.1 | 3.59e-13 |
| receptor tyrosine kinase binding | Hs | molecular function | 70.1 | 3.59e-13 |
| cytoplasmic vesicle | Hs | cellular component | 70.1 | 3.59e-13 |
| ubiquitin protein ligase binding | Hs | molecular function | 70.1 | 3.59e-13 |
| ionotropic glutamate receptor binding | Hs | molecular function | 70.1 | 3.59e-13 |
| SH2 domain binding | Hs | molecular function | 70.1 | 3.59e-13 |
| identical protein binding | Hs | molecular function | 70.1 | 3.59e-13 |
| protein homodimerization activity | Hs | molecular function | 70.1 | 3.59e-13 |
| ubiquitin binding | Hs | molecular function | 70.1 | 3.59e-13 |
| intracellular membrane-bounded organelle | Hs | cellular component | 70.1 | 3.59e-13 |
| amphisome | Hs | cellular component | 70.1 | 3.59e-13 |
| autolysosome | Hs | cellular component | 70.1 | 3.59e-13 |
| metal ion binding | Hs | molecular function | 70.1 | 3.59e-13 |
| extracellular exosome | Hs | cellular component | 70.1 | 3.59e-13 |
| K63-linked polyubiquitin modification-dependent protein binding | Hs | molecular function | 70.1 | 3.59e-13 |
| sperm midpiece | Hs | cellular component | 70.1 | 3.59e-13 |
| Lewy body | Hs | cellular component | 70.1 | 3.59e-13 |
GO (InterProScan)
1 result
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein binding | SUPERFAMILY | molecular function | 1.17E-12 |
