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GENE CARD

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Gene Card

Best human hits

IRAK1; IRAK4; PSME3

Species

M.oculata

Unique Gene ID

Moocul.g00013075

Gene Model ID

Moocul.CG.ELv1_2.S113763.g13075

Location

S113763:75467..80492

Transcript Models and Sequences

  Moocul.CG.ELv1_2.S113763.g13075.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

11 results

IPR Term Analysis Definition
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Prot_kinase_dom SMART Protein kinase domain
Proteasome_activ_sf SUPERFAMILY Proteasome activator superfamily
DEATH-like_dom_sf SUPERFAMILY Death-like domain superfamily
Death_domain Pfam Death domain
Ser/Thr_kinase_AS ProSitePatterns Serine/threonine-protein kinase, active site
Prot_kinase_dom ProSiteProfiles Protein kinase domain
PA28_C_sf Gene3D Proteasome activator PA28, C-terminal domain superfamily
Proteasome_activ_PA28_N Pfam Proteasome activator PA28, N-terminal domain
PA28_C Pfam Proteasome activator PA28, C-terminal domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

32 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
nucleotide binding Hs molecular function
magnesium ion binding Hs molecular function
cytokine production Hs biological process
toll-like receptor signaling pathway Hs biological process
immune system process Hs biological process
neutrophil mediated immunity Hs biological process
MyD88-dependent toll-like receptor signaling pathway Hs biological process
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
interleukin-1 receptor binding Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
extracellular space Hs cellular component
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
protein phosphorylation Hs biological process
signal transduction Hs biological process
JNK cascade Hs biological process
endosome membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
transferase activity Hs molecular function
cytokine-mediated signaling pathway Hs biological process
toll-like receptor 9 signaling pathway Hs biological process
positive regulation of I-kappaB kinase/NF-kappaB signaling Hs biological process
innate immune response Hs biological process
positive regulation of NF-kappaB transcription factor activity Hs biological process
interleukin-1-mediated signaling pathway Hs biological process
neutrophil migration Hs biological process

GO (Blast)

30 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 229 3.16e-67
magnesium ion binding Hs molecular function 229 3.16e-67
proteasome complex Hs cellular component 171 3.92e-48
p53 binding Hs molecular function 171 3.92e-48
protein kinase activity Hs molecular function 229 3.16e-67
protein serine/threonine kinase activity Hs molecular function 229 3.16e-67
NF-kappaB-inducing kinase activity Hs molecular function 140 1.71e-34
interleukin-1 receptor binding Hs molecular function 229 3.16e-67
protein binding Hs molecular function 229 3.16e-67
ATP binding Hs molecular function 229 3.16e-67
extracellular space Hs cellular component 229 3.16e-67
intracellular Hs cellular component 229 3.16e-67
nucleus Hs cellular component 229 3.16e-67
nucleoplasm Hs cellular component 171 3.92e-48
cytoplasm Hs cellular component 229 3.16e-67
lipid droplet Hs cellular component 140 1.71e-34
cytosol Hs cellular component 229 3.16e-67
plasma membrane Hs cellular component 229 3.16e-67
proteasome activator complex Hs cellular component 171 3.92e-48
endosome membrane Hs cellular component 229 3.16e-67
membrane Hs cellular component 171 3.92e-48
kinase activity Hs molecular function 229 3.16e-67
transferase activity Hs molecular function 229 3.16e-67
heat shock protein binding Hs molecular function 140 1.71e-34
identical protein binding Hs molecular function 171 3.92e-48
protein homodimerization activity Hs molecular function 140 1.71e-34
interleukin-1 receptor complex Hs cellular component 140 1.71e-34
protein heterodimerization activity Hs molecular function 140 1.71e-34
endopeptidase activator activity Hs molecular function 171 3.92e-48
MDM2/MDM4 family protein binding Hs molecular function 171 3.92e-48

GO (InterProScan)

6 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 2.5E-42
protein binding Pfam molecular function 4.9E-5
ATP binding SMART molecular function 5.7E-34
protein phosphorylation Pfam biological process 2.5E-42
signal transduction Pfam biological process 4.9E-5
proteasome activator complex SUPERFAMILY cellular component 4.19E-56