Gene Card
Best human hits
IRAK1; IRAK4; PSME3
Species
Unique Gene ID
Moocul.g00013075
Gene Model ID
Moocul.CG.ELv1_2.S113763.g13075
Location
S113763:75467..80492
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Ser-Thr/Tyr_kinase_cat_dom | Pfam | Serine-threonine/tyrosine-protein kinase, catalytic domain |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Prot_kinase_dom | SMART | Protein kinase domain |
Proteasome_activ_sf | SUPERFAMILY | Proteasome activator superfamily |
DEATH-like_dom_sf | SUPERFAMILY | Death-like domain superfamily |
Death_domain | Pfam | Death domain |
Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
PA28_C_sf | Gene3D | Proteasome activator PA28, C-terminal domain superfamily |
Proteasome_activ_PA28_N | Pfam | Proteasome activator PA28, N-terminal domain |
PA28_C | Pfam | Proteasome activator PA28, C-terminal domain |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
magnesium ion binding | Hs | molecular function |
cytokine production | Hs | biological process |
toll-like receptor signaling pathway | Hs | biological process |
immune system process | Hs | biological process |
neutrophil mediated immunity | Hs | biological process |
MyD88-dependent toll-like receptor signaling pathway | Hs | biological process |
protein kinase activity | Hs | molecular function |
protein serine/threonine kinase activity | Hs | molecular function |
interleukin-1 receptor binding | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
extracellular space | Hs | cellular component |
intracellular | Hs | cellular component |
nucleus | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
protein phosphorylation | Hs | biological process |
signal transduction | Hs | biological process |
JNK cascade | Hs | biological process |
endosome membrane | Hs | cellular component |
kinase activity | Hs | molecular function |
phosphorylation | Hs | biological process |
transferase activity | Hs | molecular function |
cytokine-mediated signaling pathway | Hs | biological process |
toll-like receptor 9 signaling pathway | Hs | biological process |
positive regulation of I-kappaB kinase/NF-kappaB signaling | Hs | biological process |
innate immune response | Hs | biological process |
positive regulation of NF-kappaB transcription factor activity | Hs | biological process |
interleukin-1-mediated signaling pathway | Hs | biological process |
neutrophil migration | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 229 | 3.16e-67 |
magnesium ion binding | Hs | molecular function | 229 | 3.16e-67 |
proteasome complex | Hs | cellular component | 171 | 3.92e-48 |
p53 binding | Hs | molecular function | 171 | 3.92e-48 |
protein kinase activity | Hs | molecular function | 229 | 3.16e-67 |
protein serine/threonine kinase activity | Hs | molecular function | 229 | 3.16e-67 |
NF-kappaB-inducing kinase activity | Hs | molecular function | 140 | 1.71e-34 |
interleukin-1 receptor binding | Hs | molecular function | 229 | 3.16e-67 |
protein binding | Hs | molecular function | 229 | 3.16e-67 |
ATP binding | Hs | molecular function | 229 | 3.16e-67 |
extracellular space | Hs | cellular component | 229 | 3.16e-67 |
intracellular | Hs | cellular component | 229 | 3.16e-67 |
nucleus | Hs | cellular component | 229 | 3.16e-67 |
nucleoplasm | Hs | cellular component | 171 | 3.92e-48 |
cytoplasm | Hs | cellular component | 229 | 3.16e-67 |
lipid droplet | Hs | cellular component | 140 | 1.71e-34 |
cytosol | Hs | cellular component | 229 | 3.16e-67 |
plasma membrane | Hs | cellular component | 229 | 3.16e-67 |
proteasome activator complex | Hs | cellular component | 171 | 3.92e-48 |
endosome membrane | Hs | cellular component | 229 | 3.16e-67 |
membrane | Hs | cellular component | 171 | 3.92e-48 |
kinase activity | Hs | molecular function | 229 | 3.16e-67 |
transferase activity | Hs | molecular function | 229 | 3.16e-67 |
heat shock protein binding | Hs | molecular function | 140 | 1.71e-34 |
identical protein binding | Hs | molecular function | 171 | 3.92e-48 |
protein homodimerization activity | Hs | molecular function | 140 | 1.71e-34 |
interleukin-1 receptor complex | Hs | cellular component | 140 | 1.71e-34 |
protein heterodimerization activity | Hs | molecular function | 140 | 1.71e-34 |
endopeptidase activator activity | Hs | molecular function | 171 | 3.92e-48 |
MDM2/MDM4 family protein binding | Hs | molecular function | 171 | 3.92e-48 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 2.5E-42 |
protein binding | Pfam | molecular function | 4.9E-5 |
ATP binding | SMART | molecular function | 5.7E-34 |
protein phosphorylation | Pfam | biological process | 2.5E-42 |
signal transduction | Pfam | biological process | 4.9E-5 |
proteasome activator complex | SUPERFAMILY | cellular component | 4.19E-56 |