Gene Card
Best human hits
SLC6A2; SLC6A3; SLC6A4
Unique Gene ID
Cirobu.g00001402
Gene Model ID
KH2012:KH.C10.200
Location
KhC10:4408677..4419112
Transcript Models and Sequences
KH2012:KH.C10.200.v1.A.SL1-1
KH2012:KH.C10.200.v1.A.SL3-1
KH2012:KH.C10.200.v1.A.SL4-1
KH2012:KH.C10.200.v2.A.nonSL10-1
KH2012:KH.C10.200.v2.A.nonSL5-1
KH2012:KH.C10.200.v2.A.nonSL6-1
KH2012:KH.C10.200.v2.A.nonSL7-1
KH2012:KH.C10.200.v2.A.nonSL8-1
KH2012:KH.C10.200.v2.A.nonSL9-1
KH2012:KH.C10.200.v2.A.SL2-1
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000007757 |
ENSEMBL | ENSCING00000021806 |
NCBI Reference Sequence | XM_018813827.1 |
cima89468
Plate: VES57_J17
cima876351
Plate: VES67_C23
cits033n09
Plate: R1CiGC34a12
n/a
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IPR Term | Analysis | Definition |
---|---|---|
Na/ntran_symport | Pfam | Sodium:neurotransmitter symporter |
SNS_sf | SUPERFAMILY | Sodium:neurotransmitter symporter superfamily |
Na/ntran_symport | ProSitePatterns | Sodium:neurotransmitter symporter |
Na/ntran_symport | PRINTS | Sodium:neurotransmitter symporter |
Na/ntran_symport | PANTHER | Sodium:neurotransmitter symporter |
Na/ntran_symport | ProSiteProfiles | Sodium:neurotransmitter symporter |
GO Term | Annotation Origin | Type |
---|---|---|
response to hypoxia | Orthology | biological process |
receptor binding | Blast | molecular function |
protein binding | Orthology | molecular function |
cytoplasm | Blast | cellular component |
endosome | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
integral component of plasma membrane | Orthology | cellular component |
chemical synaptic transmission | Orthology | biological process |
brain development | Orthology | biological process |
cell surface | Blast | cellular component |
response to organic substance | Orthology | biological process |
positive regulation of gene expression | Orthology | biological process |
endomembrane system | Orthology | cellular component |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
axon | Blast | cellular component |
protein homodimerization activity | Orthology | molecular function |
neuron projection | Orthology | cellular component |
neuronal cell body | Blast | cellular component |
membrane raft | Orthology | cellular component |
metal ion binding | Orthology | molecular function |
protein N-terminus binding | Blast | molecular function |
actin filament binding | Orthology | molecular function |
protein oligomerization | Orthology | biological process |
protein homooligomerization | Orthology | biological process |
transmembrane transport | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
sodium ion transport | Orthology | biological process |
organic substance transport | Orthology | biological process |
synapse part | Orthology | cellular component |
neuron part | Orthology | cellular component |
cation transport | Orthology | biological process |
nervous system process | Orthology | biological process |
intracellular organelle part | Orthology | cellular component |
whole membrane | Orthology | cellular component |
bounding membrane of organelle | Orthology | cellular component |
cytoskeletal protein binding | Orthology | molecular function |
enzyme binding | Orthology | molecular function |
cation binding | Orthology | molecular function |
heterocyclic compound binding | Orthology | molecular function |
organic cyclic compound binding | Orthology | molecular function |
response to lipid | Orthology | biological process |
cellular biosynthetic process | Orthology | biological process |
sexual reproduction | Orthology | biological process |
multicellular organismal reproductive process | Orthology | biological process |
cell development | Orthology | biological process |
neuron differentiation | Orthology | biological process |
cell cycle | Orthology | biological process |
developmental process | Orthology | biological process |
anatomical structure morphogenesis | Orthology | biological process |
binding | Blast | molecular function |
plasma membrane region | Blast | cellular component |
macromolecular complex | Blast | cellular component |
tubulin binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
response to hypoxia | Hs | biological process |
neurotransmitter:sodium symporter activity | Hs | molecular function |
dopamine:sodium symporter activity | Hs | molecular function |
serotonin:sodium symporter activity | Hs | molecular function |
protein binding | Hs | molecular function |
endosome | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
integral component of plasma membrane | Hs | cellular component |
neurotransmitter transport | Hs | biological process |
serotonin transport | Hs | biological process |
brain development | Hs | biological process |
response to nutrient | Hs | biological process |
memory | Hs | biological process |
circadian rhythm | Hs | biological process |
monoamine transmembrane transporter activity | Hs | molecular function |
response to toxic substance | Hs | biological process |
endosome membrane | Hs | cellular component |
response to organic substance | Hs | biological process |
positive regulation of gene expression | Hs | biological process |
endomembrane system | Hs | cellular component |
serotonin transmembrane transporter activity | Hs | molecular function |
symporter activity | Hs | molecular function |
monoamine transport | Hs | biological process |
membrane | Hs | cellular component |
integral component of membrane | Hs | cellular component |
myosin binding | Hs | molecular function |
syntaxin-1 binding | Hs | molecular function |
Rab GTPase binding | Hs | molecular function |
cocaine binding | Hs | molecular function |
response to estradiol | Hs | biological process |
social behavior | Hs | biological process |
neurotransmitter biosynthetic process | Hs | biological process |
vasoconstriction | Hs | biological process |
response to drug | Hs | biological process |
sperm ejaculation | Hs | biological process |
protein homodimerization activity | Hs | molecular function |
neuron projection | Hs | cellular component |
membrane raft | Hs | cellular component |
negative regulation of neuron differentiation | Hs | biological process |
positive regulation of cell cycle | Hs | biological process |
negative regulation of organ growth | Hs | biological process |
metal ion binding | Hs | molecular function |
brain morphogenesis | Hs | biological process |
nitric-oxide synthase binding | Hs | molecular function |
actin filament binding | Hs | molecular function |
protein oligomerization | Hs | biological process |
protein homooligomerization | Hs | biological process |
dopamine uptake involved in synaptic transmission | Hs | biological process |
serotonin uptake | Hs | biological process |
transmembrane transport | Hs | biological process |
cellular response to retinoic acid | Hs | biological process |
cellular response to organic substance | Hs | biological process |
cellular response to cGMP | Hs | biological process |
presynapse | Hs | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
protease binding | Hs | molecular function | 580 | 0.0 |
receptor binding | Hs | molecular function | 580 | 0.0 |
neurotransmitter:sodium symporter activity | Hs | molecular function | 667 | 0.0 |
dopamine transmembrane transporter activity | Hs | molecular function | 580 | 0.0 |
dopamine:sodium symporter activity | Hs | molecular function | 667 | 0.0 |
norepinephrine transmembrane transporter activity | Hs | molecular function | 637 | 0.0 |
norepinephrine:sodium symporter activity | Hs | molecular function | 637 | 0.0 |
serotonin:sodium symporter activity | Hs | molecular function | 667 | 0.0 |
protein binding | Hs | molecular function | 667 | 0.0 |
cytoplasm | Hs | cellular component | 580 | 0.0 |
endosome | Hs | cellular component | 667 | 0.0 |
cytosol | Hs | cellular component | 667 | 0.0 |
plasma membrane | Hs | cellular component | 667 | 0.0 |
integral component of plasma membrane | Hs | cellular component | 667 | 0.0 |
drug binding | Hs | molecular function | 580 | 0.0 |
monoamine transmembrane transporter activity | Hs | molecular function | 667 | 0.0 |
cell surface | Hs | cellular component | 637 | 0.0 |
endosome membrane | Hs | cellular component | 667 | 0.0 |
endomembrane system | Hs | cellular component | 667 | 0.0 |
serotonin transmembrane transporter activity | Hs | molecular function | 667 | 0.0 |
symporter activity | Hs | molecular function | 667 | 0.0 |
membrane | Hs | cellular component | 667 | 0.0 |
integral component of membrane | Hs | cellular component | 667 | 0.0 |
flotillin complex | Hs | cellular component | 580 | 0.0 |
myosin binding | Hs | molecular function | 667 | 0.0 |
syntaxin-1 binding | Hs | molecular function | 667 | 0.0 |
Rab GTPase binding | Hs | molecular function | 667 | 0.0 |
cocaine binding | Hs | molecular function | 667 | 0.0 |
axon | Hs | cellular component | 580 | 0.0 |
dopamine binding | Hs | molecular function | 580 | 0.0 |
protein homodimerization activity | Hs | molecular function | 667 | 0.0 |
neuron projection | Hs | cellular component | 667 | 0.0 |
alpha-tubulin binding | Hs | molecular function | 637 | 0.0 |
neuronal cell body | Hs | cellular component | 580 | 0.0 |
membrane raft | Hs | cellular component | 667 | 0.0 |
metal ion binding | Hs | molecular function | 667 | 0.0 |
protein N-terminus binding | Hs | molecular function | 580 | 0.0 |
beta-tubulin binding | Hs | molecular function | 637 | 0.0 |
nitric-oxide synthase binding | Hs | molecular function | 667 | 0.0 |
actin filament binding | Hs | molecular function | 667 | 0.0 |
protein phosphatase 2A binding | Hs | molecular function | 580 | 0.0 |
presynapse | Hs | cellular component | 667 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
neurotransmitter:sodium symporter activity | PANTHER | molecular function | 2.2E-238 |
neurotransmitter transport | PANTHER | biological process | 2.2E-238 |
integral component of membrane | PANTHER | cellular component | 2.2E-238 |