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GENE CARD

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Gene Card

Best human hits

SQSTM1

Species

H.roretzi

Unique Gene ID

Harore.g00001552

Gene Model ID

Harore.CG.MTP2014.S38.g01552

Location

S38:428481..431891

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

6 results

IPR Term Analysis Definition
UBA-like_sf SUPERFAMILY UBA-like superfamily
SQSTM_UBA Pfam Sequestosome-1, UBA domain
SQSTM_UBA CDD Sequestosome-1, UBA domain
PB1_dom ProSiteProfiles PB1 domain
PB1_dom SMART PB1 domain
PB1_dom Pfam PB1 domain

GOSlim

52 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
immune system process Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
lysosome Orthology cellular component
endosome Orthology cellular component
endoplasmic reticulum Orthology cellular component
cytosol Orthology cellular component
protein phosphorylation Orthology biological process
apoptotic process Orthology biological process
protein localization Orthology biological process
zinc ion binding Orthology molecular function
enzyme binding Orthology molecular function
protein kinase binding Orthology molecular function
cell differentiation Orthology biological process
cytoplasmic vesicle Orthology cellular component
ubiquitin protein ligase binding Orthology molecular function
intracellular signal transduction Orthology biological process
identical protein binding Orthology molecular function
protein homodimerization activity Orthology molecular function
positive regulation of apoptotic process Orthology biological process
negative regulation of apoptotic process Orthology biological process
intracellular membrane-bounded organelle Orthology cellular component
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
metal ion binding Orthology molecular function
extracellular exosome Orthology cellular component
cytoplasmic part Orthology cellular component
organelle organization Orthology biological process
intracellular non-membrane-bounded organelle Orthology cellular component
macromolecular complex Orthology cellular component
response to stress Orthology biological process
vacuole Orthology cellular component
proteolysis Orthology biological process
intracellular transport Orthology biological process
intracellular part Orthology cellular component
nuclear body Orthology cellular component
organelle part Orthology cellular component
receptor binding Orthology molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
regulation of signal transduction Orthology biological process
small GTPase mediated signal transduction Orthology biological process
protein oligomerization Orthology biological process
cytokine-mediated signaling pathway Orthology biological process
cell projection part Orthology cellular component
microtubule Orthology cellular component
plasma membrane region Orthology cellular component
neuron part Orthology cellular component
cellular response to stress Orthology biological process
protein localization to membrane Orthology biological process

GO (Orthology)

66 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
pre-autophagosomal structure Hs cellular component
autophagy of mitochondrion Hs biological process
mitophagy Hs biological process
P-body Hs cellular component
positive regulation of protein phosphorylation Hs biological process
immune system process Hs biological process
response to ischemia Hs biological process
protein serine/threonine kinase activity Hs molecular function
protein kinase C binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
lysosome Hs cellular component
endosome Hs cellular component
late endosome Hs cellular component
autophagosome Hs cellular component
endoplasmic reticulum Hs cellular component
cytosol Hs cellular component
protein phosphorylation Hs biological process
ubiquitin-dependent protein catabolic process Hs biological process
autophagy Hs biological process
apoptotic process Hs biological process
endosome organization Hs biological process
protein localization Hs biological process
zinc ion binding Hs molecular function
regulation of mitochondrion organization Hs biological process
endosomal transport Hs biological process
inclusion body Hs cellular component
aggresome Hs cellular component
macroautophagy Hs biological process
PML body Hs cellular component
enzyme binding Hs molecular function
protein kinase binding Hs molecular function
sarcomere Hs cellular component
cell differentiation Hs biological process
receptor tyrosine kinase binding Hs molecular function
cytoplasmic vesicle Hs cellular component
ubiquitin protein ligase binding Hs molecular function
ionotropic glutamate receptor binding Hs molecular function
intracellular signal transduction Hs biological process
aggrephagy Hs biological process
SH2 domain binding Hs molecular function
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
positive regulation of apoptotic process Hs biological process
negative regulation of apoptotic process Hs biological process
regulation of I-kappaB kinase/NF-kappaB signaling Hs biological process
ubiquitin binding Hs molecular function
intracellular membrane-bounded organelle Hs cellular component
negative regulation of growth of symbiont in host Hs biological process
amphisome Hs cellular component
autolysosome Hs cellular component
positive regulation of transcription from RNA polymerase II promoter Hs biological process
regulation of Ras protein signal transduction Hs biological process
metal ion binding Hs molecular function
protein heterooligomerization Hs biological process
regulation of protein complex stability Hs biological process
extracellular exosome Hs cellular component
interleukin-1-mediated signaling pathway Hs biological process
K63-linked polyubiquitin modification-dependent protein binding Hs molecular function
sperm midpiece Hs cellular component
Lewy body Hs cellular component
response to mitochondrial depolarisation Hs biological process
positive regulation of protein localization to plasma membrane Hs biological process

GO (Blast)

37 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
pre-autophagosomal structure Hs cellular component 144 6.58e-39
P-body Hs cellular component 144 6.58e-39
protein serine/threonine kinase activity Hs molecular function 144 6.58e-39
protein kinase C binding Hs molecular function 144 6.58e-39
protein binding Hs molecular function 144 6.58e-39
nucleus Hs cellular component 144 6.58e-39
nucleoplasm Hs cellular component 144 6.58e-39
cytoplasm Hs cellular component 144 6.58e-39
lysosome Hs cellular component 144 6.58e-39
endosome Hs cellular component 144 6.58e-39
late endosome Hs cellular component 144 6.58e-39
autophagosome Hs cellular component 144 6.58e-39
endoplasmic reticulum Hs cellular component 144 6.58e-39
cytosol Hs cellular component 144 6.58e-39
zinc ion binding Hs molecular function 144 6.58e-39
inclusion body Hs cellular component 144 6.58e-39
aggresome Hs cellular component 144 6.58e-39
PML body Hs cellular component 144 6.58e-39
enzyme binding Hs molecular function 144 6.58e-39
protein kinase binding Hs molecular function 144 6.58e-39
sarcomere Hs cellular component 144 6.58e-39
receptor tyrosine kinase binding Hs molecular function 144 6.58e-39
cytoplasmic vesicle Hs cellular component 144 6.58e-39
ubiquitin protein ligase binding Hs molecular function 144 6.58e-39
ionotropic glutamate receptor binding Hs molecular function 144 6.58e-39
SH2 domain binding Hs molecular function 144 6.58e-39
identical protein binding Hs molecular function 144 6.58e-39
protein homodimerization activity Hs molecular function 144 6.58e-39
ubiquitin binding Hs molecular function 144 6.58e-39
intracellular membrane-bounded organelle Hs cellular component 144 6.58e-39
amphisome Hs cellular component 144 6.58e-39
autolysosome Hs cellular component 144 6.58e-39
metal ion binding Hs molecular function 144 6.58e-39
extracellular exosome Hs cellular component 144 6.58e-39
K63-linked polyubiquitin modification-dependent protein binding Hs molecular function 144 6.58e-39
sperm midpiece Hs cellular component 144 6.58e-39
Lewy body Hs cellular component 144 6.58e-39

GO (InterProScan)

1 result

GO Term Analysis Type e-value
protein binding SUPERFAMILY molecular function 5.03E-15