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GENE CARD

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Gene Card

Best human hits

AC243734.1; AC254952.1; CHRNA7

Species

H.roretzi

Unique Gene ID

Harore.g00008140

Gene Model ID

Harore.CG.MTP2014.S37.g08140

Location

S37:367401..377186

Transcript Models and Sequences

  Harore.CG.MTP2014.S37.g08140.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

11 results

IPR Term Analysis Definition
Neuro-gated_channel_TM_sf SUPERFAMILY Neurotransmitter-gated ion-channel transmembrane domain superfamily
Neur_channel TIGRFAM Neurotransmitter-gated ion-channel
Neur_chan_lig-bd Pfam Neurotransmitter-gated ion-channel ligand-binding domain
TYR_PHOSPHATASE_dom ProSiteProfiles Tyrosine specific protein phosphatases domain
Neur_channel PANTHER Neurotransmitter-gated ion-channel
Neurotransmitter_ion_chnl_CS ProSitePatterns Neurotransmitter-gated ion-channel, conserved site
Nicotinic_acetylcholine_rcpt PRINTS Nicotinic acetylcholine receptor
Neur_channel PRINTS Neurotransmitter-gated ion-channel
Neurotrans-gated_channel_TM Pfam Neurotransmitter-gated ion-channel transmembrane domain
Neur_chan_lig-bd_sf SUPERFAMILY Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Neur_chan_lig-bd_sf Gene3D Neurotransmitter-gated ion-channel ligand-binding domain superfamily

GOSlim

55 results

GO Term Annotation Origin Type
response to hypoxia Orthology biological process
transmembrane signaling receptor activity Orthology molecular function
protein binding Orthology molecular function
plasma membrane Orthology cellular component
ion transport Orthology biological process
signal transduction Orthology biological process
positive regulation of cell proliferation Orthology biological process
membrane Orthology cellular component
integral component of membrane Orthology cellular component
apical plasma membrane Orthology cellular component
cell junction Orthology cellular component
protein homodimerization activity Orthology molecular function
synapse Orthology cellular component
postsynaptic membrane Orthology cellular component
postsynapse Orthology cellular component
dephosphorylation InterProScan biological process
positive regulation of catalytic activity Orthology biological process
intracellular signal transduction Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
positive regulation of signal transduction Orthology biological process
binding Orthology molecular function
protein phosphorylation Orthology biological process
transmembrane transport Orthology biological process
metal ion transport Orthology biological process
integral component of plasma membrane Orthology cellular component
macromolecular complex Orthology cellular component
cellular process Orthology biological process
cell Orthology cellular component
membrane organization Orthology biological process
organelle organization Orthology biological process
chemical synaptic transmission Orthology biological process
nervous system process Orthology biological process
response to stress Orthology biological process
plasma membrane part Orthology cellular component
cell surface Orthology cellular component
cation binding Orthology molecular function
molecular function regulator Orthology molecular function
cell surface receptor signaling pathway Orthology biological process
cation transport Orthology biological process
signaling receptor activity Orthology molecular function
reproductive process Orthology biological process
cell motility Orthology biological process
axon Orthology cellular component
cell projection membrane Orthology cellular component
cell leading edge Orthology cellular component
regulation of signaling Orthology biological process
immune system process Orthology biological process
membrane raft Orthology cellular component
plasma membrane region Orthology cellular component
response to organic substance Orthology biological process
angiogenesis Orthology biological process
defense response Orthology biological process
cellular component organization Orthology biological process
regulation of cell death Orthology biological process
hydrolase activity InterProScan molecular function

GO (Orthology)

64 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
activation of MAPK activity Hs biological process
amyloid-beta binding Hs molecular function
response to hypoxia Hs biological process
negative regulation of protein phosphorylation Hs biological process
positive regulation of protein phosphorylation Hs biological process
transmembrane signaling receptor activity Hs molecular function
ion channel activity Hs molecular function
extracellular ligand-gated ion channel activity Hs molecular function
calcium channel activity Hs molecular function
protein binding Hs molecular function
plasma membrane Hs cellular component
acetylcholine-gated channel complex Hs cellular component
ion transport Hs biological process
calcium ion transport Hs biological process
cellular calcium ion homeostasis Hs biological process
endocytosis Hs biological process
signal transduction Hs biological process
synaptic transmission, cholinergic Hs biological process
learning or memory Hs biological process
memory Hs biological process
short-term memory Hs biological process
positive regulation of cell proliferation Hs biological process
associative learning Hs biological process
response to cold Hs biological process
external side of plasma membrane Hs cellular component
ligand-gated ion channel activity Hs molecular function
acetylcholine receptor activity Hs molecular function
toxic substance binding Hs molecular function
membrane Hs cellular component
integral component of membrane Hs cellular component
apical plasma membrane Hs cellular component
chloride channel regulator activity Hs molecular function
acetylcholine-gated cation-selective channel activity Hs molecular function
cell junction Hs cellular component
flagellated sperm motility Hs biological process
axolemma Hs cellular component
response to food Hs biological process
regulation of synaptic transmission, dopaminergic Hs biological process
positive regulation of peptidyl-serine phosphorylation Hs biological process
ion transmembrane transport Hs biological process
response to nicotine Hs biological process
behavioral response to nicotine Hs biological process
T cell activation Hs biological process
B cell activation Hs biological process
acetylcholine binding Hs molecular function
regulation of membrane potential Hs biological process
protein homodimerization activity Hs molecular function
plasma membrane raft Hs cellular component
synapse Hs cellular component
postsynaptic membrane Hs cellular component
response to ethanol Hs biological process
positive regulation of angiogenesis Hs biological process
behavioral response to ethanol Hs biological process
regulation of inflammatory response Hs biological process
negative regulation of inflammatory response Hs biological process
modulation of chemical synaptic transmission Hs biological process
synapse organization Hs biological process
cognition Hs biological process
regulation of postsynaptic membrane potential Hs biological process
excitatory postsynaptic potential Hs biological process
positive regulation of ERK1 and ERK2 cascade Hs biological process
calcium ion transmembrane transport Hs biological process
postsynapse Hs cellular component
regulation of neuron death Hs biological process

GO (Blast)

25 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
amyloid-beta binding Hs molecular function 359 1.26e-119
transmembrane signaling receptor activity Hs molecular function 359 4.78e-120
ion channel activity Hs molecular function 359 4.78e-120
extracellular ligand-gated ion channel activity Hs molecular function 359 4.78e-120
calcium channel activity Hs molecular function 359 1.26e-119
protein binding Hs molecular function 359 1.26e-119
plasma membrane Hs cellular component 359 4.78e-120
acetylcholine-gated channel complex Hs cellular component 359 1.26e-119
external side of plasma membrane Hs cellular component 359 1.26e-119
ligand-gated ion channel activity Hs molecular function 359 1.26e-119
acetylcholine receptor activity Hs molecular function 359 1.26e-119
toxic substance binding Hs molecular function 359 1.26e-119
membrane Hs cellular component 359 4.78e-120
integral component of membrane Hs cellular component 359 4.78e-120
apical plasma membrane Hs cellular component 359 1.26e-119
chloride channel regulator activity Hs molecular function 359 1.26e-119
acetylcholine-gated cation-selective channel activity Hs molecular function 359 4.78e-120
cell junction Hs cellular component 359 4.78e-120
axolemma Hs cellular component 359 1.26e-119
acetylcholine binding Hs molecular function 359 1.26e-119
protein homodimerization activity Hs molecular function 359 1.26e-119
plasma membrane raft Hs cellular component 359 1.26e-119
synapse Hs cellular component 359 4.78e-120
postsynaptic membrane Hs cellular component 359 4.78e-120
postsynapse Hs cellular component 359 1.26e-119

GO (InterProScan)

10 results

GO Term Analysis Type e-value
transmembrane signaling receptor activity PANTHER molecular function 4.1E-127
ion channel activity PANTHER molecular function 4.1E-127
extracellular ligand-gated ion channel activity Gene3D molecular function 2.9E-81
ion transport Gene3D biological process 2.9E-81
integral component of membrane PANTHER cellular component 4.1E-127
acetylcholine-gated cation-selective channel activity PRINTS molecular function 4.5E-16
ion transmembrane transport PANTHER biological process 4.1E-127
postsynaptic membrane PRINTS cellular component 4.5E-16
dephosphorylation ProSiteProfiles biological process 9.049
phosphatase activity ProSiteProfiles molecular function 9.049