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Gene Card

Best human hits

PLCB1; PLCB2; PLCB3

Species

H.roretzi

Unique Gene ID

Harore.g00001931

Gene Model ID

Harore.CG.MTP2014.S296.g01931

Location

S296:28715..60466

Transcript Models and Sequences

  Harore.CG.MTP2014.S296.g01931.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

18 results

IPR Term Analysis Definition
PLipase_C_PInositol-sp_X_dom Pfam Phosphatidylinositol-specific phospholipase C, X domain
PLipase_C_PInositol-sp_X_dom ProSiteProfiles Phosphatidylinositol-specific phospholipase C, X domain
PLC-like_Pdiesterase_TIM-brl SUPERFAMILY PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
PLC-beta PIRSF Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta
PLC-beta_PH CDD PLC-beta, PH domain
C2_domain_sf Gene3D C2 domain superfamily
EF-hand-dom_pair SUPERFAMILY EF-hand domain pair
PLC_EF-hand-like Pfam Phosphoinositide-specific phospholipase C, EF-hand-like domain
EF_Hand_1_Ca_BS ProSitePatterns EF-Hand 1, calcium-binding site
PLipase_C_Pinositol-sp_Y SMART Phospholipase C, phosphatidylinositol-specific, Y domain
C2_dom SMART C2 domain
PLipase_C_Pinositol-sp_Y Pfam Phospholipase C, phosphatidylinositol-specific, Y domain
C2_dom ProSiteProfiles C2 domain
PLipase_C_PInositol-sp_X_dom SMART Phosphatidylinositol-specific phospholipase C, X domain
PLipase_C_Pinositol-sp_Y ProSiteProfiles Phospholipase C, phosphatidylinositol-specific, Y domain
PI-PLC_fam PANTHER Phosphoinositide phospholipase C family
PLC-like_Pdiesterase_TIM-brl Gene3D PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
PI-PLC_fam PRINTS Phosphoinositide phospholipase C family

GOSlim

52 results

GO Term Annotation Origin Type
G2/M transition of mitotic cell cycle Orthology biological process
signal transducer activity Orthology molecular function
GTPase activator activity Orthology molecular function
calcium ion binding Orthology molecular function
protein binding Orthology molecular function
calmodulin binding Orthology molecular function
intracellular Orthology cellular component
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
signal transduction Orthology biological process
G-protein coupled receptor signaling pathway Orthology biological process
brain development Orthology biological process
membrane Orthology cellular component
nuclear speck Orthology cellular component
hydrolase activity Orthology molecular function
enzyme binding Orthology molecular function
nuclear membrane Orthology cellular component
macromolecular complex Orthology cellular component
intracellular signal transduction Orthology biological process
protein homodimerization activity Orthology molecular function
myelin sheath Orthology cellular component
positive regulation of GTPase activity Orthology biological process
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription, DNA-templated Orthology biological process
metal ion binding Orthology molecular function
extracellular exosome Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
nuclear lumen Orthology cellular component
anion binding Orthology molecular function
organic substance metabolic process Orthology biological process
phosphate-containing compound metabolic process Orthology biological process
positive regulation of hydrolase activity Orthology biological process
cellular response to organic substance Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cell-cell signaling Orthology biological process
nervous system process Orthology biological process
regulation of signal transduction Orthology biological process
multicellular organism development Orthology biological process
cell adhesion molecule binding Orthology molecular function
cell differentiation Orthology biological process
anatomical structure development Orthology biological process
cellular response to stress Orthology biological process
positive regulation of signal transduction Orthology biological process
protein phosphorylation Orthology biological process
developmental process Orthology biological process
sensory perception Orthology biological process
cell cycle Orthology biological process
cytokine-mediated signaling pathway Orthology biological process
sexual reproduction Orthology biological process
G1/S transition of mitotic cell cycle Orthology biological process

GO (Orthology)

57 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
G2/M transition of mitotic cell cycle Hs biological process
nuclear chromatin Hs cellular component
phosphatidylinositol phospholipase C activity Hs molecular function
phospholipase C activity Hs molecular function
signal transducer activity Hs molecular function
GTPase activator activity Hs molecular function
calcium ion binding Hs molecular function
protein binding Hs molecular function
calmodulin binding Hs molecular function
lamin binding Hs molecular function
phosphatidylinositol-4,5-bisphosphate binding Hs molecular function
intracellular Hs cellular component
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
lipid metabolic process Hs biological process
phospholipid metabolic process Hs biological process
signal transduction Hs biological process
G-protein coupled receptor signaling pathway Hs biological process
activation of phospholipase C activity Hs biological process
G-protein coupled acetylcholine receptor signaling pathway Hs biological process
Wnt signaling pathway, calcium modulating pathway Hs biological process
brain development Hs biological process
memory Hs biological process
phosphoric diester hydrolase activity Hs molecular function
regulation of G-protein coupled receptor protein signaling pathway Hs biological process
membrane Hs cellular component
lipid catabolic process Hs biological process
nuclear speck Hs cellular component
hydrolase activity Hs molecular function
enzyme binding Hs molecular function
cerebral cortex development Hs biological process
nuclear membrane Hs cellular component
macromolecular complex Hs cellular component
intracellular signal transduction Hs biological process
positive regulation of embryonic development Hs biological process
protein homodimerization activity Hs molecular function
myelin sheath Hs cellular component
positive regulation of GTPase activity Hs biological process
cadherin binding Hs molecular function
fat cell differentiation Hs biological process
positive regulation of myoblast differentiation Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of JNK cascade Hs biological process
phosphatidylinositol metabolic process Hs biological process
metal ion binding Hs molecular function
insulin-like growth factor receptor signaling pathway Hs biological process
positive regulation of developmental growth Hs biological process
sensory perception of bitter taste Hs biological process
regulation of cell cycle Hs biological process
extracellular exosome Hs cellular component
interleukin-1-mediated signaling pathway Hs biological process
regulation of fertilization Hs biological process
positive regulation of G1/S transition of mitotic cell cycle Hs biological process
positive regulation of acrosome reaction Hs biological process

GO (Blast)

27 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nuclear chromatin Hs cellular component 458 2.28e-140
phosphatidylinositol phospholipase C activity Hs molecular function 466 3.30e-143
phospholipase C activity Hs molecular function 466 3.30e-143
signal transducer activity Hs molecular function 466 3.30e-143
GTPase activator activity Hs molecular function 458 2.28e-140
calcium ion binding Hs molecular function 466 3.30e-143
protein binding Hs molecular function 466 3.30e-143
calmodulin binding Hs molecular function 466 3.30e-143
lamin binding Hs molecular function 458 2.28e-140
phosphatidylinositol-4,5-bisphosphate binding Hs molecular function 458 2.28e-140
intracellular Hs cellular component 460 2.73e-141
nucleus Hs cellular component 458 2.28e-140
nucleoplasm Hs cellular component 466 3.30e-143
cytoplasm Hs cellular component 460 2.73e-141
cytosol Hs cellular component 466 3.30e-143
phosphoric diester hydrolase activity Hs molecular function 466 3.30e-143
membrane Hs cellular component 466 3.30e-143
nuclear speck Hs cellular component 458 2.28e-140
hydrolase activity Hs molecular function 466 3.30e-143
enzyme binding Hs molecular function 458 2.28e-140
nuclear membrane Hs cellular component 458 2.28e-140
macromolecular complex Hs cellular component 466 3.30e-143
protein homodimerization activity Hs molecular function 458 2.28e-140
myelin sheath Hs cellular component 458 2.28e-140
cadherin binding Hs molecular function 466 3.30e-143
metal ion binding Hs molecular function 460 2.73e-141
extracellular exosome Hs cellular component 458 2.28e-140

GO (InterProScan)

6 results

GO Term Analysis Type e-value
phosphatidylinositol phospholipase C activity PIRSF molecular function 2.0E-176
calcium ion binding PIRSF molecular function 2.0E-176
lipid metabolic process SUPERFAMILY biological process 1.18E-125
signal transduction SMART biological process 7.1E-67
phosphoric diester hydrolase activity SUPERFAMILY molecular function 1.18E-125
intracellular signal transduction PANTHER biological process 0.0

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