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GENE CARD

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Gene Card

Best human hits

EPHA4; EPHB1; EPHB2

Species

C.savignyi

Unique Gene ID

Cisavi.g00004167

Gene Model ID

Cisavi.CG.ENS81.R2.305036-327173

Location

R2:305035..327173

Transcript Models and Sequences

  Cisavi.CG.ENS81.R2.305036-327173.06273.t
Cisavi.CG.ENS81.R2.305036-327173.06274.t
Cisavi.CG.ENS81.R2.305036-327173.06275.t
Cisavi.CG.ENS81.R2.305036-327173.06276.t
Cisavi.CG.ENS81.R2.305036-327173.06277.t
Cisavi.CG.ENS81.R2.305036-327173.06278.t
Cisavi.CG.ENS81.R2.305036-327173.06279.t
Cisavi.CG.ENS81.R2.305036-327173.06280.t
Cisavi.CG.ENS81.R2.305036-327173.06281.t
Cisavi.CG.ENS81.R2.305036-327173.06282.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

26 results

IPR Term Analysis Definition
FN3_dom CDD Fibronectin type III
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Tyr-kin_ephrin_A/B_rcpt-like Pfam Tyrosine-protein kinase ephrin type A/B receptor-like
FN3_sf SUPERFAMILY Fibronectin type III superfamily
FN3_dom SMART Fibronectin type III
Ig-like_fold Gene3D Immunoglobulin-like fold
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain
Ephrin_rcpt_lig-bd_dom Pfam Ephrin receptor ligand binding domain
Tyr_kinase_AS ProSitePatterns Tyrosine-protein kinase, active site
Ephrin_rcpt_lig-bd_dom SMART Ephrin receptor ligand binding domain
FN3_dom Pfam Fibronectin type III
Growth_fac_rcpt_cys_sf SUPERFAMILY Growth factor receptor cysteine-rich domain superfamily
Tyr_kinase_cat_dom SMART Tyrosine-protein kinase, catalytic domain
Ephrin_rcpt_lig-bd_dom ProSiteProfiles Ephrin receptor ligand binding domain
Galactose-bd-like_sf Gene3D Galactose-binding-like domain superfamily
SAM/pointed_sf SUPERFAMILY Sterile alpha motif/pointed domain superfamily
Tyr-kin_ephrin_A/B_rcpt-like SMART Tyrosine-protein kinase ephrin type A/B receptor-like
Eph_TM Pfam Ephrin receptor, transmembrane domain
FN3_dom ProSiteProfiles Fibronectin type III
SAM Pfam Sterile alpha motif domain
Galactose-bd-like_sf SUPERFAMILY Galactose-binding-like domain superfamily
SAM SMART Sterile alpha motif domain
Tyr_kinase_ephrin_rcpt PIRSF Ephrin receptor type-A /type-B
Ser-Thr/Tyr_kinase_cat_dom PRINTS Serine-threonine/tyrosine-protein kinase, catalytic domain
SAM ProSiteProfiles Sterile alpha motif domain
Prot_kinase_dom ProSiteProfiles Protein kinase domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

No result

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type

GO (Blast)

56 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 771 0.0
amyloid-beta binding Hs molecular function 771 0.0
protein kinase activity Hs molecular function 771 0.0
protein tyrosine kinase activity Hs molecular function 771 0.0
transmembrane receptor protein tyrosine kinase activity Hs molecular function 771 0.0
receptor activity Hs molecular function 771 0.0
ephrin receptor activity Hs molecular function 771 0.0
GPI-linked ephrin receptor activity Hs molecular function 754 0.0
transmembrane-ephrin receptor activity Hs molecular function 771 0.0
receptor binding Hs molecular function 771 0.0
protein binding Hs molecular function 771 0.0
ATP binding Hs molecular function 771 0.0
extracellular region Hs cellular component 771 0.0
nucleus Hs cellular component 771 0.0
cytoplasm Hs cellular component 754 0.0
mitochondrial outer membrane Hs cellular component 754 0.0
endosome Hs cellular component 754 0.0
early endosome Hs cellular component 754 0.0
endoplasmic reticulum Hs cellular component 754 0.0
Golgi apparatus Hs cellular component 754 0.0
cytosol Hs cellular component 771 0.0
plasma membrane Hs cellular component 771 0.0
integral component of plasma membrane Hs cellular component 771 0.0
axon guidance receptor activity Hs molecular function 771 0.0
cell surface Hs cellular component 754 0.0
postsynaptic density Hs cellular component 754 0.0
membrane Hs cellular component 771 0.0
integral component of membrane Hs cellular component 771 0.0
kinase activity Hs molecular function 771 0.0
transferase activity Hs molecular function 771 0.0
cell junction Hs cellular component 754 0.0
filopodium Hs cellular component 754 0.0
axon Hs cellular component 771 0.0
dendrite Hs cellular component 771 0.0
neuromuscular junction Hs cellular component 754 0.0
early endosome membrane Hs cellular component 754 0.0
filopodium tip Hs cellular component 733 0.0
PH domain binding Hs molecular function 754 0.0
identical protein binding Hs molecular function 771 0.0
cell projection Hs cellular component 771 0.0
neuronal cell body Hs cellular component 771 0.0
dendritic spine Hs cellular component 754 0.0
dendritic shaft Hs cellular component 754 0.0
perikaryon Hs cellular component 754 0.0
axon terminus Hs cellular component 754 0.0
axonal growth cone Hs cellular component 754 0.0
cell body Hs cellular component 754 0.0
macromolecular complex binding Hs molecular function 771 0.0
membrane raft Hs cellular component 733 0.0
synapse Hs cellular component 754 0.0
postsynaptic membrane Hs cellular component 754 0.0
ephrin receptor binding Hs molecular function 754 0.0
extracellular exosome Hs cellular component 733 0.0
DH domain binding Hs molecular function 754 0.0
postsynapse Hs cellular component 771 0.0
protein tyrosine kinase binding Hs molecular function 754 0.0

GO (InterProScan)

8 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 1.3E-87
protein tyrosine kinase activity SMART molecular function 7.5E-117
ephrin receptor activity PIRSF molecular function 0.0
protein binding Pfam molecular function 4.1E-46
ATP binding ProSiteProfiles molecular function 34.633
integral component of plasma membrane PIRSF cellular component 0.0
protein phosphorylation SMART biological process 8.0E-116
transmembrane receptor protein tyrosine kinase signaling pathway PIRSF biological process 0.0

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