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GENE CARD

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Gene Card

Best human hits

IRAK1; IRAK2; IRAK4

Species

B.schlosseri

Unique Gene ID

Boschl.g00012319

Gene Model ID

Boschl.CG.Botznik2013.chr7.g12319

Location

chr7:12075336..12083775

Transcript Models and Sequences

  Boschl.CG.Botznik2013.chr7.g12319.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site
Death_domain SMART Death domain
DEATH-like_dom_sf SUPERFAMILY Death-like domain superfamily
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Death_domain Pfam Death domain
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

32 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
nucleotide binding Hs molecular function
magnesium ion binding Hs molecular function
cytokine production Hs biological process
toll-like receptor signaling pathway Hs biological process
immune system process Hs biological process
neutrophil mediated immunity Hs biological process
MyD88-dependent toll-like receptor signaling pathway Hs biological process
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
interleukin-1 receptor binding Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
extracellular space Hs cellular component
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
protein phosphorylation Hs biological process
signal transduction Hs biological process
JNK cascade Hs biological process
endosome membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
transferase activity Hs molecular function
cytokine-mediated signaling pathway Hs biological process
toll-like receptor 9 signaling pathway Hs biological process
positive regulation of I-kappaB kinase/NF-kappaB signaling Hs biological process
innate immune response Hs biological process
positive regulation of NF-kappaB transcription factor activity Hs biological process
interleukin-1-mediated signaling pathway Hs biological process
neutrophil migration Hs biological process

GO (Blast)

23 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 140 1.79e-37
magnesium ion binding Hs molecular function 140 1.79e-37
protein kinase activity Hs molecular function 140 1.79e-37
protein serine/threonine kinase activity Hs molecular function 140 1.79e-37
NF-kappaB-inducing kinase activity Hs molecular function 92.8 2.84e-20
interleukin-1 receptor binding Hs molecular function 140 1.79e-37
protein binding Hs molecular function 140 1.79e-37
ATP binding Hs molecular function 140 1.79e-37
extracellular space Hs cellular component 140 1.79e-37
intracellular Hs cellular component 140 1.79e-37
nucleus Hs cellular component 140 1.79e-37
cytoplasm Hs cellular component 140 1.79e-37
lipid droplet Hs cellular component 92.8 2.84e-20
cytosol Hs cellular component 140 1.79e-37
plasma membrane Hs cellular component 140 1.79e-37
endosome membrane Hs cellular component 140 1.79e-37
membrane Hs cellular component 92.8 2.84e-20
kinase activity Hs molecular function 140 1.79e-37
transferase activity Hs molecular function 140 1.79e-37
heat shock protein binding Hs molecular function 92.8 2.84e-20
protein homodimerization activity Hs molecular function 92.8 2.84e-20
interleukin-1 receptor complex Hs cellular component 92.8 2.84e-20
protein heterodimerization activity Hs molecular function 92.8 2.84e-20

GO (InterProScan)

5 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 2.4E-24
protein binding SMART molecular function 3.5E-6
ATP binding ProSiteProfiles molecular function 20.457
protein phosphorylation Pfam biological process 2.4E-24
signal transduction SMART biological process 3.5E-6

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