Gene Card
Best human hits
AKR1A1; AKR1C4; GCLM
Species
Unique Gene ID
Boschl.g00007924
Gene Model ID
Boschl.CG.Botznik2013.chr10.g07924
Location
chr10:14738970..14744568
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
4 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Gclm | PANTHER | Glutamate--cysteine ligase regulatory subunit |
| NADP_OxRdtase_dom | Pfam | NADP-dependent oxidoreductase domain |
| NADP_OxRdtase_dom_sf | Gene3D | NADP-dependent oxidoreductase domain superfamily |
| NADP_OxRdtase_dom_sf | SUPERFAMILY | NADP-dependent oxidoreductase domain superfamily |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
22 results
GO (Blast)
22 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| retinal dehydrogenase activity | Hs | molecular function | 46.6 | 7.09e-06 |
| alditol:NADP+ 1-oxidoreductase activity | Hs | molecular function | 56.6 | 3.55e-09 |
| aldo-keto reductase (NADP) activity | Hs | molecular function | 56.6 | 3.55e-09 |
| glutamate-cysteine ligase activity | Hs | molecular function | 192 | 4.98e-60 |
| protein binding | Hs | molecular function | 56.6 | 3.55e-09 |
| extracellular space | Hs | cellular component | 56.6 | 3.55e-09 |
| cytoplasm | Hs | cellular component | 46.6 | 7.09e-06 |
| cytosol | Hs | cellular component | 192 | 4.98e-60 |
| alcohol dehydrogenase (NADP+) activity | Hs | molecular function | 56.6 | 3.55e-09 |
| electron carrier activity | Hs | molecular function | 56.6 | 3.55e-09 |
| bile acid transmembrane transporter activity | Hs | molecular function | 46.6 | 7.09e-06 |
| apical plasma membrane | Hs | cellular component | 56.6 | 3.55e-09 |
| oxidoreductase activity | Hs | molecular function | 56.6 | 3.55e-09 |
| oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | Hs | molecular function | 46.6 | 7.09e-06 |
| glutamate-cysteine ligase complex | Hs | cellular component | 192 | 4.98e-60 |
| enzyme regulator activity | Hs | molecular function | 192 | 4.98e-60 |
| glutamate-cysteine ligase catalytic subunit binding | Hs | molecular function | 192 | 4.98e-60 |
| protein heterodimerization activity | Hs | molecular function | 192 | 4.98e-60 |
| androsterone dehydrogenase activity | Hs | molecular function | 46.6 | 7.09e-06 |
| chlordecone reductase activity | Hs | molecular function | 46.6 | 7.09e-06 |
| L-glucuronate reductase activity | Hs | molecular function | 56.6 | 3.55e-09 |
| extracellular exosome | Hs | cellular component | 56.6 | 3.55e-09 |
GO (InterProScan)
2 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| glutathione biosynthetic process | PANTHER | biological process | 5.8E-70 |
| glutamate-cysteine ligase catalytic subunit binding | PANTHER | molecular function | 5.8E-70 |
