IPR Term	Analysis	Definition
SAM-dependent_MTases	SUPERFAMILY	S-adenosyl-L-methionine-dependent methyltransferase
UbiE/COQ5_MeTrFase	Pfam	UbiE/COQ5 methyltransferase
Hamartin	PANTHER	Hamartin
Hamartin	Pfam	Hamartin

GO Term	Annotation Origin	Type
binding	Orthology	molecular function
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
cytoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
cytoskeleton	Orthology	cellular component
plasma membrane	Orthology	cellular component
nervous system development	Orthology	biological process
negative regulation of cell proliferation	Orthology	biological process
membrane	Orthology	cellular component
lamellipodium	Orthology	cellular component
cell projection organization	Orthology	biological process
macromolecular complex	Orthology	cellular component
cell projection	Orthology	cellular component
intracellular membrane-bounded organelle	Orthology	cellular component
protein N-terminus binding	Orthology	molecular function
perinuclear region of cytoplasm	Orthology	cellular component
animal organ development	Orthology	biological process
anatomical structure formation involved in morphogenesis	Orthology	biological process
cell adhesion	Orthology	biological process
immune response	Orthology	biological process
intracellular non-membrane-bounded organelle	Orthology	cellular component
cytoskeletal part	Orthology	cellular component
cell periphery	Orthology	cellular component
cytoplasmic part	Orthology	cellular component
intracellular protein transport	Orthology	biological process
regulation of gene expression	Orthology	biological process
metal ion transport	Orthology	biological process
monovalent inorganic cation transport	Orthology	biological process
neuron projection development	Orthology	biological process
negative regulation of gene expression	Orthology	biological process
brain development	Orthology	biological process
cell projection part	Orthology	cellular component
axon	Orthology	cellular component
intracellular signal transduction	Orthology	biological process
negative regulation of signal transduction	Orthology	biological process
response to organic substance	Orthology	biological process
regulation of GTPase activity	Orthology	biological process
cellular process	Orthology	biological process
protein dephosphorylation	Orthology	biological process
regulation of cellular metabolic process	Orthology	biological process
cellular component organization	Orthology	biological process
regulation of catalytic activity	Orthology	biological process
protein kinase activity	Orthology	molecular function
organic substance transport	Orthology	biological process
transmembrane transport	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
cellular response to organic substance	Orthology	biological process
protein oligomerization	Orthology	biological process
organelle organization	Orthology	biological process
cell cycle	Orthology	biological process
heart development	Orthology	biological process
cell differentiation	Orthology	biological process
positive regulation of GTPase activity	Orthology	biological process
regulation of cell death	Orthology	biological process
negative regulation of cell death	Orthology	biological process
cellular response to stress	Orthology	biological process
response to oxidative stress	Orthology	biological process
transferase activity	InterProScan	molecular function
metabolic process	InterProScan	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
kidney development	Hs	biological process
neural tube closure	Hs	biological process
regulation of cell-matrix adhesion	Hs	biological process
adaptive immune response	Hs	biological process
binding	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
lipid droplet	Hs	cellular component
cytosol	Hs	cellular component
cytoskeleton	Hs	cellular component
actin filament	Hs	cellular component
plasma membrane	Hs	cellular component
cell cortex	Hs	cellular component
rRNA export from nucleus	Hs	biological process
regulation of translation	Hs	biological process
potassium ion transport	Hs	biological process
cell cycle arrest	Hs	biological process
cell-matrix adhesion	Hs	biological process
nervous system development	Hs	biological process
negative regulation of cell proliferation	Hs	biological process
adult locomotory behavior	Hs	biological process
negative regulation of neuron projection development	Hs	biological process
membrane	Hs	cellular component
positive regulation of macroautophagy	Hs	biological process
negative regulation of macroautophagy	Hs	biological process
negative regulation of translation	Hs	biological process
cerebral cortex development	Hs	biological process
lamellipodium	Hs	cellular component
cell projection organization	Hs	biological process
growth cone	Hs	cellular component
negative regulation of TOR signaling	Hs	biological process
GTPase activating protein binding	Hs	molecular function
response to insulin	Hs	biological process
macromolecular complex	Hs	cellular component
TSC1-TSC2 complex	Hs	cellular component
negative regulation of GTPase activity	Hs	biological process
myelination	Hs	biological process
cell projection	Hs	cellular component
intracellular membrane-bounded organelle	Hs	cellular component
regulation of phosphoprotein phosphatase activity	Hs	biological process
negative regulation of cell size	Hs	biological process
regulation of protein kinase activity	Hs	biological process
glucose import	Hs	biological process
negative regulation of insulin receptor signaling pathway	Hs	biological process
protein N-terminus binding	Hs	molecular function
perinuclear region of cytoplasm	Hs	cellular component
synapse organization	Hs	biological process
protein stabilization	Hs	biological process
chaperone binding	Hs	molecular function
protein heterooligomerization	Hs	biological process
regulation of stress fiber assembly	Hs	biological process
positive regulation of stress fiber assembly	Hs	biological process
regulation of cell cycle	Hs	biological process
positive regulation of focal adhesion assembly	Hs	biological process
cardiac muscle cell differentiation	Hs	biological process
activation of GTPase activity	Hs	biological process
regulation of neuron death	Hs	biological process
negative regulation of oxidative stress-induced neuron death	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
binding	Hs	molecular function	125	3.98e-29
protein binding	Hs	molecular function	125	3.98e-29
nucleus	Hs	cellular component	125	3.98e-29
cytoplasm	Hs	cellular component	125	3.98e-29
lipid droplet	Hs	cellular component	125	3.98e-29
cytosol	Hs	cellular component	125	3.98e-29
cytoskeleton	Hs	cellular component	125	3.98e-29
actin filament	Hs	cellular component	125	3.98e-29
plasma membrane	Hs	cellular component	125	3.98e-29
cell cortex	Hs	cellular component	125	3.98e-29
membrane	Hs	cellular component	125	3.98e-29
lamellipodium	Hs	cellular component	125	3.98e-29
growth cone	Hs	cellular component	125	3.98e-29
GTPase activating protein binding	Hs	molecular function	125	3.98e-29
macromolecular complex	Hs	cellular component	125	3.98e-29
TSC1-TSC2 complex	Hs	cellular component	125	3.98e-29
cell projection	Hs	cellular component	125	3.98e-29
intracellular membrane-bounded organelle	Hs	cellular component	125	3.98e-29
protein N-terminus binding	Hs	molecular function	125	3.98e-29
perinuclear region of cytoplasm	Hs	cellular component	125	3.98e-29
chaperone binding	Hs	molecular function	125	3.98e-29

GO Term	Analysis	Type	e-value
methyltransferase activity	Pfam	molecular function	2.5E-4