Gene Card
Best human hits
HM13; SPPL2A; SPPL3
Species
Unique Gene ID
Phmamm.g00013775
Gene Model ID
Phmamm.CG.MTP2014.S1124.g13775
Location
S1124:11915..19059
Transcript Models and Sequences
AHC0AAA28YD18
Plate: Plate_28_D18
AHC0AAA28YF14
Plate: Plate_28_F14
AHC0AAA31YN16
Plate: Plate_31_N16
AHC0AAA34YK15
Plate: Plate_34_K15
AHC0AAA37YF24
Plate: Plate_37_F24
AHC0AAA53YJ21
Plate: Plate_53_J21
AHC0AAA67YE09
Plate: Plate_67_E09
AHC0AAA69YO17
Plate: Plate_69_O17
AHC0AAA77YB03
Plate: Plate_77_B03
AHC0AAA107YN16
Plate: Plate_107_N16
AHC0AAA108YD15
Plate: Plate_108_D15
AHC0AAA113YK12
Plate: Plate_113_K12
AHC0AAA115YL04
Plate: Plate_115_L04
AHC0AAA116YP21
Plate: Plate_116_P21
AHC0AAA117YH23
Plate: Plate_117_H23
AHC0AAA124YJ05
Plate: Plate_124_J05
AHC0AAA126YM06
Plate: Plate_126_M06
AHC0AAA129YL19
Plate: Plate_129_L19
AHC0AAA130YA10
Plate: Plate_130_A10
AHC0AAA133YO14
Plate: Plate_133_O14
AHC0AAA135YI05
Plate: Plate_135_I05
AHC0AAA150YP09
Plate: Plate_150_P09
AHC0AAA153YP12
Plate: Plate_153_P12
AHC0AAA155YH07
Plate: Plate_155_H07
AHC0AAA155YJ08
Plate: Plate_155_J08
AHC0AAA81YO01
Plate: Plate_81_O01
AHC0AAA133YA12
Plate: Plate_133_A12
AHC0AAA180YM13
Plate: Plate_180_M13
AHC0AAA193YD01
Plate: Plate_193_D01
AHC0AAA194YB08
Plate: Plate_194_B08
AHC0AAA214YE02
Plate: Plate_214_E02
AHC0AAA217YA10
Plate: Plate_217_A10
AHC0AAA233YH09
Plate: Plate_233_H09
AHC0AAA245YJ16
Plate: Plate_245_J16
AHC0AAA255YA09
Plate: Plate_255_A09
AHC0AAA261YF22
Plate: Plate_261_F22
AHC0AAA269YH01
Plate: Plate_269_H01
n/a
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IPR Term | Analysis | Definition |
---|---|---|
Peptidase_A22B_SPP | Pfam | Peptidase A22B, signal peptide peptidase |
Peptidase_A22B_SPP | PANTHER | Peptidase A22B, signal peptide peptidase |
Preselin/SPP | SMART | Presenilin/signal peptide peptidase |
GO Term | Annotation Origin | Type |
---|---|---|
protein binding | Blast | molecular function |
lysosome | Blast | cellular component |
lysosomal membrane | Blast | cellular component |
endosome | Blast | cellular component |
endoplasmic reticulum | Blast | cellular component |
endoplasmic reticulum membrane | Blast | cellular component |
Golgi apparatus | Blast | cellular component |
plasma membrane | Blast | cellular component |
peptidase activity | Blast | molecular function |
cell surface | Blast | cellular component |
membrane | Blast | cellular component |
integral component of membrane | Blast | cellular component |
hydrolase activity | Blast | molecular function |
ubiquitin protein ligase binding | Blast | molecular function |
protein homodimerization activity | Blast | molecular function |
intracellular membrane-bounded organelle | Blast | cellular component |
extracellular exosome | Blast | cellular component |
endopeptidase activity | Blast | molecular function |
intracellular organelle part | Blast | cellular component |
whole membrane | Blast | cellular component |
cytoplasmic vesicle | Blast | cellular component |
bounding membrane of organelle | Blast | cellular component |
cytoplasmic part | Blast | cellular component |
macromolecular complex | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
aspartic-type endopeptidase activity | Hs | molecular function | 335 | 3.99e-114 |
protein binding | Hs | molecular function | 335 | 3.99e-114 |
lysosome | Hs | cellular component | 54.3 | 2.81e-08 |
lysosomal membrane | Hs | cellular component | 335 | 3.99e-114 |
endosome | Hs | cellular component | 54.3 | 2.81e-08 |
late endosome | Hs | cellular component | 54.3 | 2.81e-08 |
endoplasmic reticulum | Hs | cellular component | 335 | 3.99e-114 |
endoplasmic reticulum membrane | Hs | cellular component | 335 | 3.99e-114 |
rough endoplasmic reticulum | Hs | cellular component | 335 | 3.99e-114 |
Golgi apparatus | Hs | cellular component | 84.3 | 1.71e-18 |
plasma membrane | Hs | cellular component | 335 | 3.99e-114 |
peptidase activity | Hs | molecular function | 335 | 3.99e-114 |
cell surface | Hs | cellular component | 335 | 3.99e-114 |
membrane | Hs | cellular component | 335 | 3.99e-114 |
integral component of membrane | Hs | cellular component | 335 | 3.99e-114 |
hydrolase activity | Hs | molecular function | 335 | 3.99e-114 |
Golgi-associated vesicle membrane | Hs | cellular component | 335 | 3.99e-114 |
ubiquitin protein ligase binding | Hs | molecular function | 335 | 3.99e-114 |
late endosome membrane | Hs | cellular component | 54.3 | 2.81e-08 |
endoplasmic reticulum-Golgi intermediate compartment membrane | Hs | cellular component | 84.3 | 1.71e-18 |
Derlin-1 retrotranslocation complex | Hs | cellular component | 335 | 3.99e-114 |
aspartic endopeptidase activity, intramembrane cleaving | Hs | molecular function | 335 | 3.99e-114 |
protein homodimerization activity | Hs | molecular function | 335 | 3.99e-114 |
intracellular membrane-bounded organelle | Hs | cellular component | 84.3 | 1.71e-18 |
extracellular exosome | Hs | cellular component | 54.3 | 2.81e-08 |
integral component of cytoplasmic side of endoplasmic reticulum membrane | Hs | cellular component | 335 | 3.99e-114 |
integral component of lumenal side of endoplasmic reticulum membrane | Hs | cellular component | 335 | 3.99e-114 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
aspartic-type endopeptidase activity | PANTHER | molecular function | 8.6E-96 |
integral component of membrane | PANTHER | cellular component | 8.6E-96 |