Gene Card
Best human hits
ASH1L; NSD1; SETD2
Species
Unique Gene ID
Phmamm.g00013767
Gene Model ID
Phmamm.CG.MTP2014.S1122.g13767
Location
S1122:400..19436
Transcript Models and Sequences
Phmamm.CG.MTP2014.S1122.g13767.01.t
Phmamm.CG.MTP2014.S1122.g13767.02.t
AHC0AAA13YB01
Plate: Plate_13_B01
AHC0AAA16YB22
Plate: Plate_16_B22
AHC0AAA50YI15
Plate: Plate_50_I15
AHC0AAA54YM17
Plate: Plate_54_M17
AHC0AAA61YA15
Plate: Plate_61_A15
AHC0AAA77YG19
Plate: Plate_77_G19
AHC0AAA109YH06
Plate: Plate_109_H06
AHC0AAA138YB04
Plate: Plate_138_B04
AHC0AAA154YP09
Plate: Plate_154_P09
AHC0AAA87YK11
Plate: Plate_87_K11
AHC0AAA179YK11
Plate: Plate_179_K11
AHC0AAA212YK17
Plate: Plate_212_K17
AHC0AAA220YK16
Plate: Plate_220_K16
AHC0AAA224YH22
Plate: Plate_224_H22
AHC0AAA230YD06
Plate: Plate_230_D06
AHC0AAA258YJ14
Plate: Plate_258_J14
AHC0AAA54YO19
Plate: Plate_54_O19
n/a
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IPR Term | Analysis | Definition |
---|---|---|
Post-SET_dom | SMART | Post-SET domain |
Post-SET_dom | ProSiteProfiles | Post-SET domain |
AWS_dom | ProSiteProfiles | AWS domain |
SET_dom | ProSiteProfiles | SET domain |
SET_dom | SMART | SET domain |
AWS_dom | SMART | AWS domain |
SET_dom | Pfam | SET domain |
WW_dom | SMART | WW domain |
SRI_sf | Gene3D | Set2 Rpb1 interacting domain superfamily |
WW_dom | ProSitePatterns | WW domain |
SRI | Pfam | Set2 Rpb1 interacting domain |
WW_dom_sf | SUPERFAMILY | WW domain superfamily |
WW_dom | ProSiteProfiles | WW domain |
WW_dom | CDD | WW domain |
WW_dom | Pfam | WW domain |
GO Term | Annotation Origin | Type |
---|---|---|
RNA polymerase II core promoter proximal region sequence-specific DNA binding | Blast | molecular function |
RNA polymerase II transcription factor activity, sequence-specific DNA binding | Blast | molecular function |
angiogenesis | Orthology | biological process |
immune system process | Orthology | biological process |
DNA binding | Blast | molecular function |
chromatin binding | Blast | molecular function |
transcription cofactor activity | Blast | molecular function |
transcription corepressor activity | Blast | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
Golgi apparatus | Blast | cellular component |
DNA repair | Orthology | biological process |
transcription, DNA-templated | Orthology | biological process |
regulation of transcription, DNA-templated | Orthology | biological process |
transcription from RNA polymerase II promoter | Orthology | biological process |
cellular response to DNA damage stimulus | Orthology | biological process |
multicellular organism development | Orthology | biological process |
zinc ion binding | Blast | molecular function |
regulation of gene expression | Orthology | biological process |
transferase activity | Orthology | molecular function |
cell junction | Blast | cellular component |
cell differentiation | Orthology | biological process |
innate immune response | Orthology | biological process |
metal ion binding | Orthology | molecular function |
extracellular exosome | Blast | cellular component |
blood vessel morphogenesis | Orthology | biological process |
anatomical structure morphogenesis | Orthology | biological process |
anatomical structure formation involved in morphogenesis | Orthology | biological process |
nervous system development | Orthology | biological process |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
organelle organization | Orthology | biological process |
metabolic process | Orthology | biological process |
cellular protein modification process | Orthology | biological process |
intracellular protein transport | Orthology | biological process |
brain development | Orthology | biological process |
membrane organization | Orthology | biological process |
cell division | Orthology | biological process |
tubulin binding | Orthology | molecular function |
animal organ development | Orthology | biological process |
cell development | Orthology | biological process |
defense response | Orthology | biological process |
microtubule-based process | Orthology | biological process |
protein localization to organelle | Orthology | biological process |
receptor binding | Blast | molecular function |
transcription factor binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
RNA polymerase II core promoter proximal region sequence-specific DNA binding | Hs | molecular function | 183 | 3.66e-46 |
RNA polymerase II transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 187 | 1.96e-47 |
DNA binding | Hs | molecular function | 187 | 1.96e-47 |
chromatin binding | Hs | molecular function | 187 | 1.96e-47 |
transcription cofactor activity | Hs | molecular function | 183 | 3.66e-46 |
transcription corepressor activity | Hs | molecular function | 183 | 3.66e-46 |
protein binding | Hs | molecular function | 399 | 1.78e-113 |
nucleus | Hs | cellular component | 399 | 1.78e-113 |
nucleoplasm | Hs | cellular component | 399 | 1.78e-113 |
chromosome | Hs | cellular component | 399 | 1.78e-113 |
Golgi apparatus | Hs | cellular component | 187 | 1.96e-47 |
bicellular tight junction | Hs | cellular component | 187 | 1.96e-47 |
methyltransferase activity | Hs | molecular function | 399 | 1.78e-113 |
zinc ion binding | Hs | molecular function | 183 | 3.66e-46 |
protein-lysine N-methyltransferase activity | Hs | molecular function | 399 | 1.78e-113 |
transferase activity | Hs | molecular function | 399 | 1.78e-113 |
histone-lysine N-methyltransferase activity | Hs | molecular function | 399 | 1.78e-113 |
cell junction | Hs | cellular component | 187 | 1.96e-47 |
estrogen receptor binding | Hs | molecular function | 183 | 3.66e-46 |
histone methyltransferase activity (H4-K20 specific) | Hs | molecular function | 183 | 3.66e-46 |
histone methyltransferase activity (H3-K4 specific) | Hs | molecular function | 187 | 1.96e-47 |
retinoic acid receptor binding | Hs | molecular function | 183 | 3.66e-46 |
alpha-tubulin binding | Hs | molecular function | 399 | 1.78e-113 |
metal ion binding | Hs | molecular function | 399 | 1.78e-113 |
retinoid X receptor binding | Hs | molecular function | 183 | 3.66e-46 |
thyroid hormone receptor binding | Hs | molecular function | 183 | 3.66e-46 |
histone methyltransferase activity (H3-K36 specific) | Hs | molecular function | 399 | 1.78e-113 |
androgen receptor binding | Hs | molecular function | 183 | 3.66e-46 |
extracellular exosome | Hs | cellular component | 187 | 1.96e-47 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein binding | SMART | molecular function | 1.5E-43 |
nucleus | SMART | cellular component | 1.2E-17 |
chromosome | Pfam | cellular component | 2.3E-23 |
regulation of transcription, DNA-templated | Pfam | biological process | 2.3E-23 |
histone-lysine N-methyltransferase activity | SMART | molecular function | 1.2E-17 |
histone lysine methylation | Pfam | biological process | 2.3E-23 |