Gene Card
Best human hits
FGFR1; FGFR2; FGFR3
Species
Unique Gene ID
Phmamm.g00013441
Gene Model ID
Phmamm.CG.MTP2014.S1050.g13441
Location
S1050:4772..20926
Transcript Models and Sequences
Phmamm.CG.MTP2014.S1050.g13441.01.t
Phmamm.CG.MTP2014.S1050.g13441.02.t
AHC0AAA12YA10
Plate: Plate_12_A10
AHC0AAA25YI11
Plate: Plate_25_I11
AHC0AAA26YL20
Plate: Plate_26_L20
AHC0AAA38YM04
Plate: Plate_38_M04
AHC0AAA41YM18
Plate: Plate_41_M18
AHC0AAA48YJ17
Plate: Plate_48_J17
AHC0AAA50YF20
Plate: Plate_50_F20
AHC0AAA52YF17
Plate: Plate_52_F17
AHC0AAA63YE20
Plate: Plate_63_E20
AHC0AAA70YG15
Plate: Plate_70_G15
AHC0AAA75YJ15
Plate: Plate_75_J15
AHC0AAA103YA20
Plate: Plate_103_A20
AHC0AAA105YJ03
Plate: Plate_105_J03
AHC0AAA81YG02
Plate: Plate_81_G02
AHC0AAA174YH14
Plate: Plate_174_H14
AHC0AAA184YF15
Plate: Plate_184_F15
AHC0AAA187YG24
Plate: Plate_187_G24
AHC0AAA194YH09
Plate: Plate_194_H09
AHC0AAA197YM19
Plate: Plate_197_M19
AHC0AAA219YJ16
Plate: Plate_219_J16
AHC0AAA234YA07
Plate: Plate_234_A07
AHC0AAA236YG05
Plate: Plate_236_G05
AHC0AAA240YI06
Plate: Plate_240_I06
AHC0AAA243YO21
Plate: Plate_243_O21
AHC0AAA244YD17
Plate: Plate_244_D17
AHC0AAA248YH24
Plate: Plate_248_H24
AHC0AAA250YI03
Plate: Plate_250_I03
AHC0AAA251YC22
Plate: Plate_251_C22
AHC0AAA38YM02
Plate: Plate_38_M02
n/a
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Ig-like_dom_sf | SUPERFAMILY | Immunoglobulin-like domain superfamily |
Ig_sub | SMART | Immunoglobulin subtype |
Ig_sub2 | SMART | Immunoglobulin subtype 2 |
Ser-Thr/Tyr_kinase_cat_dom | Pfam | Serine-threonine/tyrosine-protein kinase, catalytic domain |
Ig_I-set | Pfam | Immunoglobulin I-set |
Ig-like_fold | Gene3D | Immunoglobulin-like fold |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Ig-like_dom | ProSiteProfiles | Immunoglobulin-like domain |
Tyr_kinase_AS | ProSitePatterns | Tyrosine-protein kinase, active site |
Ser-Thr/Tyr_kinase_cat_dom | PRINTS | Serine-threonine/tyrosine-protein kinase, catalytic domain |
Tyr_kinase_cat_dom | SMART | Tyrosine-protein kinase, catalytic domain |
FGF_rcpt_fam | PIRSF | Fibroblast growth factor receptor family |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
negative regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
nucleotide binding | Orthology | molecular function |
angiogenesis | Orthology | biological process |
protein kinase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
extracellular region | Orthology | cellular component |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
nucleolus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
endoplasmic reticulum | Orthology | cellular component |
Golgi apparatus | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
integral component of plasma membrane | Orthology | cellular component |
focal adhesion | Orthology | cellular component |
transcription, DNA-templated | Orthology | biological process |
regulation of transcription, DNA-templated | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
apoptotic process | Orthology | biological process |
cell-cell signaling | Orthology | biological process |
axonogenesis | Orthology | biological process |
brain development | Orthology | biological process |
sensory perception of sound | Orthology | biological process |
positive regulation of cell proliferation | Orthology | biological process |
cell surface | Orthology | cellular component |
regulation of gene expression | Orthology | biological process |
negative regulation of gene expression | Orthology | biological process |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
cell migration | Orthology | biological process |
transferase activity | Orthology | molecular function |
positive regulation of Wnt signaling pathway | Orthology | biological process |
cytoplasmic vesicle | Orthology | cellular component |
response to lipopolysaccharide | Orthology | biological process |
wound healing | Orthology | biological process |
regulation of cell proliferation | Orthology | biological process |
identical protein binding | Orthology | molecular function |
protein homodimerization activity | Orthology | molecular function |
intracellular membrane-bounded organelle | Orthology | cellular component |
positive regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
protein autophosphorylation | Orthology | biological process |
blood vessel morphogenesis | Orthology | biological process |
generation of neurons | Orthology | biological process |
positive regulation of canonical Wnt signaling pathway | Orthology | biological process |
endosome | Orthology | cellular component |
positive regulation of gene expression | Orthology | biological process |
positive regulation of catalytic activity | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
system development | Orthology | biological process |
animal organ development | Orthology | biological process |
anatomical structure formation involved in morphogenesis | Orthology | biological process |
cell differentiation | Orthology | biological process |
anatomical structure morphogenesis | Orthology | biological process |
transmembrane signaling receptor activity | Orthology | molecular function |
cell surface receptor signaling pathway | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
enzyme binding | Orthology | molecular function |
molecular function regulator | Orthology | molecular function |
cell periphery | Orthology | cellular component |
cytoplasmic part | Orthology | cellular component |
anion binding | Orthology | molecular function |
carbohydrate derivative binding | Orthology | molecular function |
regulation of signal transduction | Orthology | biological process |
multicellular organism development | Orthology | biological process |
positive regulation of hydrolase activity | Orthology | biological process |
neuron projection development | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
phosphotransferase activity, alcohol group as acceptor | Orthology | molecular function |
cellular biosynthetic process | Orthology | biological process |
endomembrane system | Orthology | cellular component |
anatomical structure development | Orthology | biological process |
extracellular region part | Orthology | cellular component |
developmental process | Orthology | biological process |
cell proliferation | Orthology | biological process |
phosphate-containing compound metabolic process | Orthology | biological process |
macromolecular complex | Orthology | cellular component |
protein serine/threonine kinase activity | Orthology | molecular function |
response to organic substance | Orthology | biological process |
cell development | Orthology | biological process |
neuron differentiation | Orthology | biological process |
cell cycle | Orthology | biological process |
organic substance metabolic process | Orthology | biological process |
reproductive process | Orthology | biological process |
nervous system development | Orthology | biological process |
negative regulation of cell proliferation | Orthology | biological process |
cell division | Orthology | biological process |
heart development | Orthology | biological process |
synapse | Orthology | cellular component |
neuron development | Orthology | biological process |
regulation of cellular metabolic process | Orthology | biological process |
response to lipid | Orthology | biological process |
receptor binding | Orthology | molecular function |
cell junction | Orthology | cellular component |
proteolysis | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 592 | 0.0 |
protein kinase activity | Hs | molecular function | 592 | 0.0 |
protein tyrosine kinase activity | Hs | molecular function | 592 | 0.0 |
transmembrane receptor protein tyrosine kinase activity | Hs | molecular function | 592 | 0.0 |
fibroblast growth factor-activated receptor activity | Hs | molecular function | 592 | 0.0 |
Ras guanyl-nucleotide exchange factor activity | Hs | molecular function | 592 | 0.0 |
protein binding | Hs | molecular function | 592 | 0.0 |
ATP binding | Hs | molecular function | 592 | 0.0 |
extracellular region | Hs | cellular component | 592 | 0.0 |
nucleus | Hs | cellular component | 592 | 0.0 |
nucleoplasm | Hs | cellular component | 563 | 0.0 |
nucleolus | Hs | cellular component | 592 | 0.0 |
cytoplasm | Hs | cellular component | 592 | 0.0 |
endoplasmic reticulum | Hs | cellular component | 555 | 0.0 |
Golgi apparatus | Hs | cellular component | 563 | 0.0 |
cytosol | Hs | cellular component | 592 | 0.0 |
plasma membrane | Hs | cellular component | 592 | 0.0 |
integral component of plasma membrane | Hs | cellular component | 592 | 0.0 |
focal adhesion | Hs | cellular component | 555 | 0.0 |
cell cortex | Hs | cellular component | 563 | 0.0 |
heparin binding | Hs | molecular function | 592 | 0.0 |
cell surface | Hs | cellular component | 563 | 0.0 |
membrane | Hs | cellular component | 592 | 0.0 |
integral component of membrane | Hs | cellular component | 592 | 0.0 |
kinase activity | Hs | molecular function | 592 | 0.0 |
1-phosphatidylinositol-3-kinase activity | Hs | molecular function | 592 | 0.0 |
transferase activity | Hs | molecular function | 592 | 0.0 |
fibroblast growth factor binding | Hs | molecular function | 592 | 0.0 |
transport vesicle | Hs | cellular component | 555 | 0.0 |
extracellular matrix | Hs | cellular component | 563 | 0.0 |
cytoplasmic vesicle | Hs | cellular component | 592 | 0.0 |
identical protein binding | Hs | molecular function | 592 | 0.0 |
protein homodimerization activity | Hs | molecular function | 592 | 0.0 |
intracellular membrane-bounded organelle | Hs | cellular component | 563 | 0.0 |
receptor complex | Hs | cellular component | 592 | 0.0 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity | Hs | molecular function | 592 | 0.0 |
excitatory synapse | Hs | cellular component | 563 | 0.0 |
receptor-receptor interaction | Hs | molecular function | 592 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 4.0E-96 |
protein tyrosine kinase activity | SMART | molecular function | 1.4E-129 |
fibroblast growth factor-activated receptor activity | PIRSF | molecular function | 7.3E-298 |
ATP binding | ProSiteProfiles | molecular function | 38.605 |
protein phosphorylation | SMART | biological process | 1.4E-129 |
positive regulation of cell proliferation | PIRSF | biological process | 7.3E-298 |
fibroblast growth factor receptor signaling pathway | PIRSF | biological process | 7.3E-298 |
integral component of membrane | PIRSF | cellular component | 7.3E-298 |