Gene Card
Best human hits
CLPX; PSMC3; YME1L1
Species
Unique Gene ID
Phmamm.g00010713
Gene Model ID
Phmamm.CG.MTP2014.S627.g10713
Location
S627:81657..87389
Transcript Models and Sequences
AHC0AAA10YK09
Plate: Plate_10_K09
AHC0AAA11YJ18
Plate: Plate_11_J18
AHC0AAA13YB20
Plate: Plate_13_B20
AHC0AAA15YH21
Plate: Plate_15_H21
AHC0AAA19YH16
Plate: Plate_19_H16
AHC0AAA2YL20
Plate: Plate_2_L20
AHC0AAA25YB02
Plate: Plate_25_B02
AHC0AAA26YK02
Plate: Plate_26_K02
AHC0AAA9YD22
Plate: Plate_9_D22
AHC0AAA31YM23
Plate: Plate_31_M23
AHC0AAA32YE06
Plate: Plate_32_E06
AHC0AAA32YO17
Plate: Plate_32_O17
AHC0AAA39YO05
Plate: Plate_39_O05
AHC0AAA47YE03
Plate: Plate_47_E03
AHC0AAA68YJ10
Plate: Plate_68_J10
AHC0AAA76YH03
Plate: Plate_76_H03
AHC0AAA122YK12
Plate: Plate_122_K12
AHC0AAA124YD06
Plate: Plate_124_D06
AHC0AAA128YP18
Plate: Plate_128_P18
AHC0AAA129YL08
Plate: Plate_129_L08
AHC0AAA136YO23
Plate: Plate_136_O23
AHC0AAA138YM07
Plate: Plate_138_M07
AHC0AAA141YP05
Plate: Plate_141_P05
AHC0AAA143YP18
Plate: Plate_143_P18
AHC0AAA147YE23
Plate: Plate_147_E23
AHC0AAA149YH17
Plate: Plate_149_H17
AHC0AAA150YL03
Plate: Plate_150_L03
AHC0AAA155YB20
Plate: Plate_155_B20
AHC0AAA82YL24
Plate: Plate_82_L24
AHC0AAA147YE21
Plate: Plate_147_E21
AHC0AAA170YP19
Plate: Plate_170_P19
AHC0AAA181YP20
Plate: Plate_181_P20
AHC0AAA186YP16
Plate: Plate_186_P16
AHC0AAA188YN14
Plate: Plate_188_N14
AHC0AAA189YC13
Plate: Plate_189_C13
AHC0AAA201YE16
Plate: Plate_201_E16
AHC0AAA205YF24
Plate: Plate_205_F24
AHC0AAA215YD17
Plate: Plate_215_D17
AHC0AAA221YN16
Plate: Plate_221_N16
AHC0AAA226YE24
Plate: Plate_226_E24
AHC0AAA235YF15
Plate: Plate_235_F15
AHC0AAA236YF23
Plate: Plate_236_F23
AHC0AAA240YJ08
Plate: Plate_240_J08
AHC0AAA250YD08
Plate: Plate_250_D08
AHC0AAA255YD22
Plate: Plate_255_D22
AHC0AAA269YM01
Plate: Plate_269_M01
AHC0AAA39YA03
Plate: Plate_39_A03
n/a
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IPR Term | Analysis | Definition |
---|---|---|
AAA+_ATPase | SMART | AAA+ ATPase domain |
Clp_protease_ATP-bd_su_ClpX | PANTHER | Clp protease, ATP-binding subunit ClpX |
ATPase_AAA_core | Pfam | ATPase, AAA-type, core |
Clp_ATPase_C | Pfam | Clp ATPase, C-terminal |
P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
Clp_ATPase_C | SMART | Clp ATPase, C-terminal |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
metalloendopeptidase activity | Blast | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
extracellular region | Blast | cellular component |
nucleus | Blast | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Blast | cellular component |
mitochondrion | Orthology | cellular component |
mitochondrial inner membrane | Orthology | cellular component |
mitochondrial matrix | Orthology | cellular component |
cytosol | Orthology | cellular component |
protein folding | Orthology | biological process |
proteolysis | Orthology | biological process |
peptidase activity | Orthology | molecular function |
metallopeptidase activity | Blast | molecular function |
membrane | Blast | cellular component |
integral component of membrane | Blast | cellular component |
nuclear body | Blast | cellular component |
hydrolase activity | Blast | molecular function |
identical protein binding | Blast | molecular function |
metal ion binding | Orthology | molecular function |
unfolded protein binding | Orthology | molecular function |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
nucleoside-triphosphatase activity | Orthology | molecular function |
intracellular part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
positive regulation of hydrolase activity | Orthology | biological process |
enzyme binding | Orthology | molecular function |
enzyme activator activity | Orthology | molecular function |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
metabolic process | Orthology | biological process |
cytoplasmic part | Blast | cellular component |
transcription factor binding | Blast | molecular function |
nuclear lumen | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
cytoplasmic vesicle | Blast | cellular component |
endomembrane system | Blast | cellular component |
intracellular organelle lumen | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
ATP-dependent peptidase activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
nucleoplasm | Hs | cellular component |
mitochondrion | Hs | cellular component |
mitochondrial inner membrane | Hs | cellular component |
mitochondrial matrix | Hs | cellular component |
cytosol | Hs | cellular component |
protein folding | Hs | biological process |
endopeptidase Clp complex | Hs | cellular component |
mitochondrial endopeptidase Clp complex | Hs | cellular component |
positive regulation of peptidase activity | Hs | biological process |
peptidase activator activity | Hs | molecular function |
ATPase activity | Hs | molecular function |
mitochondrial nucleoid | Hs | cellular component |
ATP metabolic process | Hs | biological process |
metal ion binding | Hs | molecular function |
unfolded protein binding | Hs | molecular function |
proteolysis involved in cellular protein catabolic process | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 533 | 0.0 |
proteasome complex | Hs | cellular component | 45.1 | 8.65e-05 |
P-body | Hs | cellular component | 45.1 | 8.65e-05 |
ATP-dependent peptidase activity | Hs | molecular function | 533 | 0.0 |
metalloendopeptidase activity | Hs | molecular function | 45.4 | 7.94e-05 |
protein binding | Hs | molecular function | 533 | 0.0 |
ATP binding | Hs | molecular function | 533 | 0.0 |
extracellular region | Hs | cellular component | 45.1 | 8.65e-05 |
nucleus | Hs | cellular component | 45.1 | 8.65e-05 |
nucleoplasm | Hs | cellular component | 533 | 0.0 |
cytoplasm | Hs | cellular component | 45.1 | 8.65e-05 |
mitochondrion | Hs | cellular component | 533 | 0.0 |
mitochondrial inner membrane | Hs | cellular component | 533 | 0.0 |
mitochondrial matrix | Hs | cellular component | 533 | 0.0 |
cytosol | Hs | cellular component | 533 | 0.0 |
peptidase activity | Hs | molecular function | 45.4 | 7.94e-05 |
metallopeptidase activity | Hs | molecular function | 45.4 | 7.94e-05 |
proteasome regulatory particle, base subcomplex | Hs | cellular component | 45.1 | 8.65e-05 |
endopeptidase Clp complex | Hs | cellular component | 533 | 0.0 |
mitochondrial endopeptidase Clp complex | Hs | cellular component | 533 | 0.0 |
membrane | Hs | cellular component | 45.4 | 7.94e-05 |
integral component of membrane | Hs | cellular component | 45.4 | 7.94e-05 |
peptidase activator activity | Hs | molecular function | 533 | 0.0 |
nuclear body | Hs | cellular component | 45.4 | 7.94e-05 |
hydrolase activity | Hs | molecular function | 45.4 | 7.94e-05 |
ATPase activity | Hs | molecular function | 533 | 0.0 |
TBP-class protein binding | Hs | molecular function | 45.1 | 8.65e-05 |
proteasome accessory complex | Hs | cellular component | 45.1 | 8.65e-05 |
nuclear proteasome complex | Hs | cellular component | 45.1 | 8.65e-05 |
cytosolic proteasome complex | Hs | cellular component | 45.1 | 8.65e-05 |
secretory granule lumen | Hs | cellular component | 45.1 | 8.65e-05 |
proteasome-activating ATPase activity | Hs | molecular function | 45.1 | 8.65e-05 |
mitochondrial nucleoid | Hs | cellular component | 533 | 0.0 |
identical protein binding | Hs | molecular function | 45.1 | 8.65e-05 |
metal ion binding | Hs | molecular function | 533 | 0.0 |
unfolded protein binding | Hs | molecular function | 533 | 0.0 |
ficolin-1-rich granule lumen | Hs | cellular component | 45.1 | 8.65e-05 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ATP binding | PANTHER | molecular function | 3.5E-181 |
protein folding | PANTHER | biological process | 3.5E-181 |
unfolded protein binding | PANTHER | molecular function | 3.5E-181 |