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GENE CARD

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Gene Card

Best human hits

NKX2-1; NKX2-2; NKX2-6

Species

P.mammillata

Unique Gene ID

Phmamm.g00010419

Gene Model ID

Phmamm.CG.MTP2014.S597.g10419

Location

S597:19780..26412

Transcript Models and Sequences

  Phmamm.CG.MTP2014.S597.g10419.02.t
Phmamm.CG.MTP2014.S597.g10419.03.t

External Database Gene Card

External database links

No result

Collections

Genoscope Yasuo Villefranche

1 result

AHC0AAA267YK08

Plate: Plate_267_K08

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

5 results

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
Homeobox_metazoa PRINTS Homeobox domain, metazoa
Homeobox-like_sf SUPERFAMILY Homeobox-like domain superfamily
Homeobox_dom ProSiteProfiles Homeobox domain
Homeobox_dom CDD Homeobox domain
Homeobox_dom SMART Homeobox domain
Homeobox_dom Pfam Homeobox domain
Homeobox_CS ProSitePatterns Homeobox, conserved site

GOSlim

45 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
RNA polymerase II regulatory region sequence-specific DNA binding Orthology molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
core promoter proximal region sequence-specific DNA binding Blast molecular function
RNA polymerase II regulatory region DNA binding Orthology molecular function
DNA binding Orthology molecular function
chromatin binding Blast molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcription coactivator activity Blast molecular function
protein binding Orthology molecular function
intracellular Blast cellular component
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
multicellular organism development Orthology biological process
axon guidance Orthology biological process
brain development Orthology biological process
transcription factor binding Blast molecular function
positive regulation of gene expression Orthology biological process
enzyme binding Orthology molecular function
cell differentiation Orthology biological process
sequence-specific DNA binding Orthology molecular function
transcription regulatory region DNA binding Orthology molecular function
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
anatomical structure formation involved in morphogenesis Orthology biological process
cell migration Orthology biological process
generation of neurons Orthology biological process
intracellular part Orthology cellular component
macromolecular complex Orthology cellular component
phosphate-containing compound metabolic process Orthology biological process
organic substance metabolic process Orthology biological process
anatomical structure development Orthology biological process
response to organic substance Orthology biological process
animal organ development Orthology biological process
anatomical structure morphogenesis Orthology biological process
neuron differentiation Orthology biological process
cell surface receptor signaling pathway Orthology biological process
negative regulation of signal transduction Orthology biological process
cellular response to organic substance Orthology biological process
neurogenesis Orthology biological process
central nervous system development Orthology biological process

GO (Orthology)

51 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
RNA polymerase II regulatory region DNA binding Hs molecular function
core promoter binding Hs molecular function
intronic transcription regulatory region sequence-specific DNA binding Hs molecular function
neuron migration Hs biological process
DNA binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
transcription factor complex Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
regulation of transcription from RNA polymerase II promoter Hs biological process
phospholipid metabolic process Hs biological process
multicellular organism development Hs biological process
pattern specification process Hs biological process
axon guidance Hs biological process
brain development Hs biological process
endoderm development Hs biological process
locomotory behavior Hs biological process
response to hormone Hs biological process
animal organ morphogenesis Hs biological process
positive regulation of gene expression Hs biological process
negative regulation of epithelial to mesenchymal transition Hs biological process
enzyme binding Hs molecular function
telencephalon development Hs biological process
forebrain dorsal/ventral pattern formation Hs biological process
forebrain neuron differentiation Hs biological process
cerebral cortex neuron differentiation Hs biological process
pituitary gland development Hs biological process
telencephalon cell migration Hs biological process
lung development Hs biological process
negative regulation of cell migration Hs biological process
negative regulation of transforming growth factor beta receptor signaling pathway Hs biological process
thyroid gland development Hs biological process
forebrain development Hs biological process
positive regulation of circadian rhythm Hs biological process
sequence-specific DNA binding Hs molecular function
transcription regulatory region DNA binding Hs molecular function
intronic transcription regulatory region DNA binding Hs molecular function
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
rhythmic process Hs biological process
anatomical structure formation involved in morphogenesis Hs biological process
neuron fate commitment Hs biological process
oligodendrocyte differentiation Hs biological process

GO (Blast)

21 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function 181 6.92e-52
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 181 6.92e-52
core promoter proximal region sequence-specific DNA binding Hs molecular function 117 9.04e-30
RNA polymerase II regulatory region DNA binding Hs molecular function 181 6.92e-52
core promoter binding Hs molecular function 181 6.92e-52
intronic transcription regulatory region sequence-specific DNA binding Hs molecular function 181 6.92e-52
DNA binding Hs molecular function 181 6.92e-52
chromatin binding Hs molecular function 117 9.04e-30
transcription factor activity, sequence-specific DNA binding Hs molecular function 181 6.92e-52
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function 181 6.92e-52
transcription coactivator activity Hs molecular function 117 9.04e-30
protein binding Hs molecular function 181 6.92e-52
intracellular Hs cellular component 117 9.04e-30
nucleus Hs cellular component 181 6.92e-52
nucleoplasm Hs cellular component 181 6.92e-52
transcription factor complex Hs cellular component 181 6.92e-52
transcription factor binding Hs molecular function 117 9.04e-30
enzyme binding Hs molecular function 181 6.92e-52
sequence-specific DNA binding Hs molecular function 181 6.92e-52
transcription regulatory region DNA binding Hs molecular function 181 6.92e-52
intronic transcription regulatory region DNA binding Hs molecular function 181 6.92e-52

GO (InterProScan)

3 results

GO Term Analysis Type e-value
DNA binding SUPERFAMILY molecular function 7.27E-24
regulation of transcription, DNA-templated ProSitePatterns biological process
sequence-specific DNA binding ProSitePatterns molecular function

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