IPR Term	Analysis	Definition
Pyrv_Knase_AS	ProSitePatterns	Pyruvate kinase, active site
Pyr_Knase	CDD	Pyruvate kinase
Pyr_Knase	PANTHER	Pyruvate kinase
Pyrv_Knase_brl	Pfam	Pyruvate kinase, barrel
Pyrv_Knase_C_sf	SUPERFAMILY	Pyruvate kinase, C-terminal domain superfamily
Pyrv_Knase_insert_dom_sf	Gene3D	Pyruvate kinase, insert domain superfamily
Pyrv/PenolPyrv_Kinase-like_dom	SUPERFAMILY	Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily
Pyr_Knase	TIGRFAM	Pyruvate kinase
Pyrv_Knase_C	Pfam	Pyruvate kinase, C-terminal
Pyrv_Knase-like_insert_dom_sf	SUPERFAMILY	Pyruvate kinase-like, insert domain superfamily
Pyr_Knase	PRINTS	Pyruvate kinase
Pyrv_Knase_C_sf	Gene3D	Pyruvate kinase, C-terminal domain superfamily

GO Term	Annotation Origin	Type
nucleotide binding	Orthology	molecular function
magnesium ion binding	Orthology	molecular function
response to hypoxia	Orthology	biological process
RNA binding	Orthology	molecular function
catalytic activity	Orthology	molecular function
protein binding	Orthology	molecular function
ATP binding	Orthology	molecular function
extracellular region	Orthology	cellular component
nucleus	Orthology	cellular component
cytoplasm	Orthology	cellular component
mitochondrion	Orthology	cellular component
cytosol	Orthology	cellular component
metabolic process	Orthology	biological process
response to organic substance	Orthology	biological process
programmed cell death	Orthology	biological process
kinase activity	Orthology	molecular function
phosphorylation	Orthology	biological process
transferase activity	Orthology	molecular function
vesicle	Orthology	cellular component
identical protein binding	Orthology	molecular function
myelin sheath	Orthology	cellular component
metal ion binding	Orthology	molecular function
extracellular exosome	Orthology	cellular component
extracellular vesicle	Orthology	cellular component
animal organ development	Orthology	biological process
phosphotransferase activity, alcohol group as acceptor	Orthology	molecular function
nucleobase-containing compound metabolic process	Orthology	biological process
oxidation-reduction process	Orthology	biological process
organelle	Orthology	cellular component
cell projection	Orthology	cellular component
plasma membrane region	Orthology	cellular component
macromolecular complex	Orthology	cellular component
organic substance metabolic process	Orthology	biological process
phosphate-containing compound metabolic process	Orthology	biological process
response to stress	Orthology	biological process
macromolecular complex binding	Orthology	molecular function
extracellular region part	Orthology	cellular component
cellular response to organic substance	Orthology	biological process
intracellular organelle part	Orthology	cellular component
cytoplasmic vesicle	Orthology	cellular component
endomembrane system	Orthology	cellular component
intracellular organelle lumen	Orthology	cellular component
cellular biosynthetic process	Orthology	biological process
anion binding	Orthology	molecular function
adenyl ribonucleotide binding	Orthology	molecular function
cell adhesion molecule binding	Orthology	molecular function
protein homooligomerization	Orthology	biological process
binding	Orthology	molecular function

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
nucleotide binding	Hs	molecular function
magnesium ion binding	Hs	molecular function
response to hypoxia	Hs	biological process
liver development	Hs	biological process
RNA binding	Hs	molecular function
catalytic activity	Hs	molecular function
pyruvate kinase activity	Hs	molecular function
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
extracellular region	Hs	cellular component
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
mitochondrion	Hs	cellular component
cytosol	Hs	cellular component
cilium	Hs	cellular component
carbohydrate metabolic process	Hs	biological process
glucose metabolic process	Hs	biological process
glycolytic process	Hs	biological process
ATP biosynthetic process	Hs	biological process
response to nutrient	Hs	biological process
metabolic process	Hs	biological process
response to heat	Hs	biological process
response to gravity	Hs	biological process
response to glucose	Hs	biological process
response to organic substance	Hs	biological process
response to metal ion	Hs	biological process
response to lithium ion	Hs	biological process
programmed cell death	Hs	biological process
kinase activity	Hs	molecular function
phosphorylation	Hs	biological process
transferase activity	Hs	molecular function
MHC class II protein complex binding	Hs	molecular function
potassium ion binding	Hs	molecular function
extracellular matrix	Hs	cellular component
animal organ regeneration	Hs	biological process
vesicle	Hs	cellular component
response to insulin	Hs	biological process
cellular response to insulin stimulus	Hs	biological process
response to ATP	Hs	biological process
secretory granule lumen	Hs	cellular component
identical protein binding	Hs	molecular function
pyruvate biosynthetic process	Hs	biological process
myelin sheath	Hs	cellular component
ADP binding	Hs	molecular function
cadherin binding	Hs	molecular function
metal ion binding	Hs	molecular function
protein homotetramerization	Hs	biological process
response to cAMP	Hs	biological process
canonical glycolysis	Hs	biological process
extracellular exosome	Hs	cellular component
thyroid hormone binding	Hs	molecular function
pyruvate kinase complex	Hs	cellular component
extracellular vesicle	Hs	cellular component
ficolin-1-rich granule lumen	Hs	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	776	0.0
magnesium ion binding	Hs	molecular function	776	0.0
RNA binding	Hs	molecular function	776	0.0
catalytic activity	Hs	molecular function	776	0.0
pyruvate kinase activity	Hs	molecular function	776	0.0
protein binding	Hs	molecular function	776	0.0
ATP binding	Hs	molecular function	776	0.0
extracellular region	Hs	cellular component	776	0.0
nucleus	Hs	cellular component	776	0.0
cytoplasm	Hs	cellular component	776	0.0
mitochondrion	Hs	cellular component	776	0.0
cytosol	Hs	cellular component	776	0.0
cilium	Hs	cellular component	776	0.0
kinase activity	Hs	molecular function	776	0.0
transferase activity	Hs	molecular function	776	0.0
MHC class II protein complex binding	Hs	molecular function	776	0.0
potassium ion binding	Hs	molecular function	776	0.0
extracellular matrix	Hs	cellular component	776	0.0
vesicle	Hs	cellular component	776	0.0
secretory granule lumen	Hs	cellular component	776	0.0
identical protein binding	Hs	molecular function	776	0.0
myelin sheath	Hs	cellular component	776	0.0
ADP binding	Hs	molecular function	776	0.0
cadherin binding	Hs	molecular function	776	0.0
metal ion binding	Hs	molecular function	776	0.0
extracellular exosome	Hs	cellular component	776	0.0
thyroid hormone binding	Hs	molecular function	776	0.0
pyruvate kinase complex	Hs	cellular component	776	0.0
extracellular vesicle	Hs	cellular component	776	0.0
ficolin-1-rich granule lumen	Hs	cellular component	776	0.0

GO Term	Analysis	Type	e-value
magnesium ion binding	PANTHER	molecular function	6.7E-211
catalytic activity	SUPERFAMILY	molecular function	2.23E-103
pyruvate kinase activity	PANTHER	molecular function	6.7E-211
glycolytic process	PANTHER	biological process	6.7E-211
potassium ion binding	PANTHER	molecular function	6.7E-211