Gene Card
Best human hits
CTSL; CTSS; CTSV
Species
Unique Gene ID
Phmamm.g00009707
Gene Model ID
Phmamm.CG.MTP2014.S520.g09707
Location
S520:94695..97663
Transcript Models and Sequences
AHC0AAA11YH11
Plate: Plate_11_H11
AHC0AAA11YP21
Plate: Plate_11_P21
AHC0AAA13YE17
Plate: Plate_13_E17
AHC0AAA22YK20
Plate: Plate_22_K20
AHC0AAA26YL05
Plate: Plate_26_L05
AHC0AAA7YG16
Plate: Plate_7_G16
AHC0AAA9YO02
Plate: Plate_9_O02
AHC0AAA35YL19
Plate: Plate_35_L19
AHC0AAA42YI03
Plate: Plate_42_I03
AHC0AAA61YH24
Plate: Plate_61_H24
AHC0AAA67YL19
Plate: Plate_67_L19
AHC0AAA72YP15
Plate: Plate_72_P15
AHC0AAA74YM22
Plate: Plate_74_M22
AHC0AAA76YO15
Plate: Plate_76_O15
AHC0AAA77YN17
Plate: Plate_77_N17
AHC0AAA116YP14
Plate: Plate_116_P14
AHC0AAA128YH21
Plate: Plate_128_H21
AHC0AAA131YB04
Plate: Plate_131_B04
AHC0AAA133YB11
Plate: Plate_133_B11
AHC0AAA135YN22
Plate: Plate_135_N22
AHC0AAA136YN21
Plate: Plate_136_N21
AHC0AAA143YA15
Plate: Plate_143_A15
AHC0AAA143YO07
Plate: Plate_143_O07
AHC0AAA146YC15
Plate: Plate_146_C15
AHC0AAA153YH09
Plate: Plate_153_H09
AHC0AAA153YJ23
Plate: Plate_153_J23
AHC0AAA87YC05
Plate: Plate_87_C05
AHC0AAA93YK16
Plate: Plate_93_K16
AHC0AAA94YA19
Plate: Plate_94_A19
AHC0AAA133YB09
Plate: Plate_133_B09
AHC0AAA164YC20
Plate: Plate_164_C20
AHC0AAA169YP08
Plate: Plate_169_P08
AHC0AAA188YO20
Plate: Plate_188_O20
AHC0AAA189YL01
Plate: Plate_189_L01
AHC0AAA211YD23
Plate: Plate_211_D23
AHC0AAA214YK24
Plate: Plate_214_K24
AHC0AAA223YB16
Plate: Plate_223_B16
AHC0AAA223YP14
Plate: Plate_223_P14
AHC0AAA225YA03
Plate: Plate_225_A03
AHC0AAA225YB15
Plate: Plate_225_B15
AHC0AAA226YI06
Plate: Plate_226_I06
AHC0AAA230YG01
Plate: Plate_230_G01
AHC0AAA231YC23
Plate: Plate_231_C23
AHC0AAA240YL06
Plate: Plate_240_L06
AHC0AAA252YL03
Plate: Plate_252_L03
AHC0AAA253YI23
Plate: Plate_253_I23
AHC0AAA253YP13
Plate: Plate_253_P13
AHC0AAA261YE22
Plate: Plate_261_E22
AHC0AAA263YM18
Plate: Plate_263_M18
n/a
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IPR Term | Analysis | Definition |
---|---|---|
Peptidase_C1A_C | Pfam | Peptidase C1A, papain C-terminal |
Prot_inhib_I29 | Pfam | Cathepsin propeptide inhibitor domain (I29) |
Peptidase_C1A_C | PRINTS | Peptidase C1A, papain C-terminal |
Pept_cys_AS | ProSitePatterns | Cysteine peptidase, cysteine active site |
Prot_inhib_I29 | SMART | Cathepsin propeptide inhibitor domain (I29) |
Pept_asp_AS | ProSitePatterns | Cysteine peptidase, asparagine active site |
Peptidase_C1A | PANTHER | Peptidase C1A |
Pept_his_AS | ProSitePatterns | Cysteine peptidase, histidine active site |
Peptidase_C1A_C | SMART | Peptidase C1A, papain C-terminal |
GO Term | Annotation Origin | Type |
---|---|---|
serine-type endopeptidase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
extracellular region | Orthology | cellular component |
extracellular space | Orthology | cellular component |
nucleus | Orthology | cellular component |
nucleolus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
lysosome | Orthology | cellular component |
vacuole | Orthology | cellular component |
proteolysis | Orthology | biological process |
immune response | Orthology | biological process |
cell communication | Orthology | biological process |
spermatogenesis | Orthology | biological process |
peptidase activity | Orthology | molecular function |
hydrolase activity | Orthology | molecular function |
cytoplasmic vesicle | Orthology | cellular component |
neuron projection | Orthology | cellular component |
intracellular membrane-bounded organelle | Orthology | cellular component |
apical part of cell | Orthology | cellular component |
extracellular exosome | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
signal transduction | Orthology | biological process |
innate immune response | Orthology | biological process |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
endopeptidase activity | Orthology | molecular function |
macromolecular complex binding | Orthology | molecular function |
plasma membrane region | Orthology | cellular component |
cell projection | Orthology | cellular component |
cytoskeletal part | Orthology | cellular component |
reproductive process | Orthology | biological process |
animal organ development | Orthology | biological process |
cellular response to stress | Orthology | biological process |
response to organic substance | Orthology | biological process |
plasma membrane part | Orthology | cellular component |
cell surface | Orthology | cellular component |
multicellular organism development | Orthology | biological process |
gene expression | Orthology | biological process |
immune system process | Orthology | biological process |
endomembrane system | Orthology | cellular component |
catabolic process | Orthology | biological process |
extracellular matrix organization | Orthology | biological process |
endosome | Orthology | cellular component |
vacuolar part | Orthology | cellular component |
intracellular organelle lumen | Orthology | cellular component |
binding | Orthology | molecular function |
neuronal cell body | Orthology | cellular component |
carbohydrate derivative binding | Orthology | molecular function |
cell differentiation | Orthology | biological process |
programmed cell death | Orthology | biological process |
response to lipid | Orthology | biological process |
intracellular organelle part | Orthology | cellular component |
organelle organization | Orthology | biological process |
transmembrane transport | Orthology | biological process |
cation transport | Orthology | biological process |
regulation of cellular metabolic process | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
fibronectin binding | Hs | molecular function |
toll-like receptor signaling pathway | Hs | biological process |
adaptive immune response | Hs | biological process |
aminopeptidase activity | Hs | molecular function |
cysteine-type endopeptidase activity | Hs | molecular function |
serine-type endopeptidase activity | Hs | molecular function |
protein binding | Hs | molecular function |
collagen binding | Hs | molecular function |
extracellular region | Hs | cellular component |
extracellular space | Hs | cellular component |
nucleus | Hs | cellular component |
nucleolus | Hs | cellular component |
cytoplasm | Hs | cellular component |
lysosome | Hs | cellular component |
vacuole | Hs | cellular component |
microvillus | Hs | cellular component |
proteolysis | Hs | biological process |
immune response | Hs | biological process |
cell communication | Hs | biological process |
spermatogenesis | Hs | biological process |
peptidase activity | Hs | molecular function |
cysteine-type peptidase activity | Hs | molecular function |
male gonad development | Hs | biological process |
cellular response to starvation | Hs | biological process |
response to glucose | Hs | biological process |
external side of plasma membrane | Hs | cellular component |
multicellular organism aging | Hs | biological process |
response to acidic pH | Hs | biological process |
response to organic cyclic compound | Hs | biological process |
protein processing | Hs | biological process |
protein autoprocessing | Hs | biological process |
hydrolase activity | Hs | molecular function |
cysteine-type carboxypeptidase activity | Hs | molecular function |
antigen processing and presentation | Hs | biological process |
antigen processing and presentation of exogenous peptide antigen via MHC class II | Hs | biological process |
secretory granule | Hs | cellular component |
collagen catabolic process | Hs | biological process |
kininogen binding | Hs | molecular function |
cytoplasmic vesicle | Hs | cellular component |
basement membrane disassembly | Hs | biological process |
endolysosome lumen | Hs | cellular component |
peptide binding | Hs | molecular function |
histone binding | Hs | molecular function |
neuron projection | Hs | cellular component |
lysosomal lumen | Hs | cellular component |
perikaryon | Hs | cellular component |
intracellular membrane-bounded organelle | Hs | cellular component |
laminin binding | Hs | molecular function |
proteoglycan binding | Hs | molecular function |
apical part of cell | Hs | cellular component |
regulation of keratinocyte differentiation | Hs | biological process |
autophagic cell death | Hs | biological process |
response to glucocorticoid | Hs | biological process |
proteolysis involved in cellular protein catabolic process | Hs | biological process |
extracellular exosome | Hs | cellular component |
serpin family protein binding | Hs | molecular function |
tertiary granule lumen | Hs | cellular component |
ficolin-1-rich granule lumen | Hs | cellular component |
response to odorant | Hs | biological process |
regulation of actin cytoskeleton reorganization | Hs | biological process |
positive regulation of cation channel activity | Hs | biological process |
intramembranous ossification | Hs | biological process |
nucleoplasm | Hs | cellular component |
bone resorption | Hs | biological process |
regulation of autophagy of mitochondrion | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
fibronectin binding | Hs | molecular function | 350 | 5.82e-121 |
aminopeptidase activity | Hs | molecular function | 340 | 6.20e-117 |
cysteine-type endopeptidase activity | Hs | molecular function | 350 | 5.82e-121 |
serine-type endopeptidase activity | Hs | molecular function | 350 | 5.82e-121 |
protein binding | Hs | molecular function | 350 | 5.82e-121 |
collagen binding | Hs | molecular function | 350 | 5.82e-121 |
extracellular region | Hs | cellular component | 350 | 5.82e-121 |
extracellular space | Hs | cellular component | 350 | 5.82e-121 |
nucleus | Hs | cellular component | 350 | 5.82e-121 |
nucleolus | Hs | cellular component | 340 | 6.20e-117 |
cytoplasm | Hs | cellular component | 340 | 6.20e-117 |
lysosome | Hs | cellular component | 350 | 5.82e-121 |
vacuole | Hs | cellular component | 340 | 6.20e-117 |
microvillus | Hs | cellular component | 340 | 6.20e-117 |
peptidase activity | Hs | molecular function | 350 | 5.82e-121 |
cysteine-type peptidase activity | Hs | molecular function | 350 | 5.82e-121 |
external side of plasma membrane | Hs | cellular component | 340 | 6.20e-117 |
hydrolase activity | Hs | molecular function | 350 | 5.82e-121 |
cysteine-type carboxypeptidase activity | Hs | molecular function | 340 | 6.20e-117 |
secretory granule | Hs | cellular component | 340 | 6.20e-117 |
kininogen binding | Hs | molecular function | 340 | 6.20e-117 |
cytoplasmic vesicle | Hs | cellular component | 340 | 6.20e-117 |
endolysosome lumen | Hs | cellular component | 350 | 5.82e-121 |
peptide binding | Hs | molecular function | 340 | 6.20e-117 |
histone binding | Hs | molecular function | 350 | 5.82e-121 |
neuron projection | Hs | cellular component | 340 | 6.20e-117 |
lysosomal lumen | Hs | cellular component | 350 | 5.82e-121 |
perikaryon | Hs | cellular component | 340 | 6.20e-117 |
intracellular membrane-bounded organelle | Hs | cellular component | 298 | 1.59e-100 |
laminin binding | Hs | molecular function | 298 | 1.59e-100 |
proteoglycan binding | Hs | molecular function | 350 | 5.82e-121 |
apical part of cell | Hs | cellular component | 340 | 6.20e-117 |
extracellular exosome | Hs | cellular component | 350 | 5.82e-121 |
serpin family protein binding | Hs | molecular function | 350 | 5.82e-121 |
tertiary granule lumen | Hs | cellular component | 298 | 1.59e-100 |
ficolin-1-rich granule lumen | Hs | cellular component | 298 | 1.59e-100 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
proteolysis | SMART | biological process | 1.5E-127 |
cysteine-type peptidase activity | SMART | molecular function | 1.5E-127 |