Gene Card
Best human hits
MAPKAPK2; MAPKAPK3; MAPKAPK5
Species
Unique Gene ID
Phmamm.g00007492
Gene Model ID
Phmamm.CG.MTP2014.S338.g07492
Location
S338:145877..153504
Transcript Models and Sequences
AHC0AAA22YH16
Plate: Plate_22_H16
AHC0AAA38YM12
Plate: Plate_38_M12
AHC0AAA40YP10
Plate: Plate_40_P10
AHC0AAA73YD01
Plate: Plate_73_D01
AHC0AAA111YB20
Plate: Plate_111_B20
AHC0AAA114YO15
Plate: Plate_114_O15
AHC0AAA136YK05
Plate: Plate_136_K05
AHC0AAA146YB11
Plate: Plate_146_B11
AHC0AAA156YL02
Plate: Plate_156_L02
AHC0AAA98YC06
Plate: Plate_98_C06
AHC0AAA177YB06
Plate: Plate_177_B06
AHC0AAA186YK04
Plate: Plate_186_K04
AHC0AAA213YG24
Plate: Plate_213_G24
AHC0AAA252YE14
Plate: Plate_252_E14
AHC0AAA38YM10
Plate: Plate_38_M10
AHC0AAA98YE08
Plate: Plate_98_E08
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Prot_kinase_dom | SMART | Protein kinase domain |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
Prot_kinase_dom | Pfam | Protein kinase domain |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
protein kinase activity | Orthology | molecular function |
protein serine/threonine kinase activity | Orthology | molecular function |
signal transducer activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
calmodulin binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
centrosome | Orthology | cellular component |
cytosol | Orthology | cellular component |
protein phosphorylation | Orthology | biological process |
cellular response to DNA damage stimulus | Orthology | biological process |
signal transduction | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
transferase activity | Orthology | molecular function |
response to lipopolysaccharide | Orthology | biological process |
response to cytokine | Orthology | biological process |
protein autophosphorylation | Orthology | biological process |
extracellular exosome | Orthology | cellular component |
intracellular signal transduction | Orthology | biological process |
positive regulation of catalytic activity | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
innate immune response | Orthology | biological process |
cellular metabolic process | Orthology | biological process |
organic substance metabolic process | Orthology | biological process |
defense response | Orthology | biological process |
small GTPase mediated signal transduction | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
cellular response to stress | Orthology | biological process |
mRNA catabolic process | Orthology | biological process |
membrane organization | Orthology | biological process |
organelle organization | Orthology | biological process |
positive regulation of gene expression | Orthology | biological process |
animal organ development | Orthology | biological process |
protein kinase binding | Orthology | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
MAPK cascade | Hs | biological process |
nucleotide binding | Hs | molecular function |
activation of MAPK activity | Hs | biological process |
toll-like receptor signaling pathway | Hs | biological process |
protein kinase activity | Hs | molecular function |
protein serine/threonine kinase activity | Hs | molecular function |
calmodulin-dependent protein kinase activity | Hs | molecular function |
MAP kinase kinase activity | Hs | molecular function |
signal transducer activity | Hs | molecular function |
protein binding | Hs | molecular function |
calmodulin binding | Hs | molecular function |
ATP binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
cytoplasm | Hs | cellular component |
centrosome | Hs | cellular component |
cytosol | Hs | cellular component |
protein phosphorylation | Hs | biological process |
leukotriene metabolic process | Hs | biological process |
inflammatory response | Hs | biological process |
cellular response to DNA damage stimulus | Hs | biological process |
signal transduction | Hs | biological process |
cell surface receptor signaling pathway | Hs | biological process |
Ras protein signal transduction | Hs | biological process |
calcium-dependent protein serine/threonine kinase activity | Hs | molecular function |
kinase activity | Hs | molecular function |
phosphorylation | Hs | biological process |
transferase activity | Hs | molecular function |
peptidyl-serine phosphorylation | Hs | biological process |
response to lipopolysaccharide | Hs | biological process |
response to cytokine | Hs | biological process |
cellular response to vascular endothelial growth factor stimulus | Hs | biological process |
p38MAPK cascade | Hs | biological process |
regulation of mRNA stability | Hs | biological process |
macropinocytosis | Hs | biological process |
protein autophosphorylation | Hs | biological process |
vascular endothelial growth factor receptor signaling pathway | Hs | biological process |
mRNA stabilization | Hs | biological process |
inner ear development | Hs | biological process |
mitogen-activated protein kinase binding | Hs | molecular function |
extracellular exosome | Hs | cellular component |
3'-UTR-mediated mRNA stabilization | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 309 | 9.42e-106 |
p53 binding | Hs | molecular function | 175 | 2.09e-52 |
protein kinase activity | Hs | molecular function | 309 | 9.42e-106 |
protein serine/threonine kinase activity | Hs | molecular function | 309 | 9.42e-106 |
calmodulin-dependent protein kinase activity | Hs | molecular function | 309 | 9.42e-106 |
MAP kinase kinase activity | Hs | molecular function | 309 | 9.42e-106 |
signal transducer activity | Hs | molecular function | 304 | 1.32e-103 |
protein binding | Hs | molecular function | 309 | 9.42e-106 |
calmodulin binding | Hs | molecular function | 309 | 9.42e-106 |
ATP binding | Hs | molecular function | 309 | 9.42e-106 |
nucleus | Hs | cellular component | 309 | 9.42e-106 |
nucleoplasm | Hs | cellular component | 309 | 9.42e-106 |
cytoplasm | Hs | cellular component | 309 | 9.42e-106 |
centrosome | Hs | cellular component | 304 | 1.32e-103 |
cytosol | Hs | cellular component | 309 | 9.42e-106 |
calcium-dependent protein serine/threonine kinase activity | Hs | molecular function | 309 | 9.42e-106 |
kinase activity | Hs | molecular function | 309 | 9.42e-106 |
transferase activity | Hs | molecular function | 309 | 9.42e-106 |
mitogen-activated protein kinase binding | Hs | molecular function | 309 | 9.42e-106 |
extracellular exosome | Hs | cellular component | 304 | 1.32e-103 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 2.7E-51 |
ATP binding | Pfam | molecular function | 2.7E-51 |
protein phosphorylation | Pfam | biological process | 2.7E-51 |