IPR Term	Analysis	Definition
Ser-Thr/Tyr_kinase_cat_dom	Pfam	Serine-threonine/tyrosine-protein kinase, catalytic domain
Protein_kinase_ATP_BS	ProSitePatterns	Protein kinase, ATP binding site
Death_domain	Pfam	Death domain
DEATH-like_dom_sf	SUPERFAMILY	Death-like domain superfamily
Prot_kinase_dom	ProSiteProfiles	Protein kinase domain
Prot_kinase_dom	SMART	Protein kinase domain
Kinase-like_dom_sf	SUPERFAMILY	Protein kinase-like domain superfamily
Ser/Thr_kinase_AS	ProSitePatterns	Serine/threonine-protein kinase, active site

GO Term	Annotation Origin	Type
nucleotide binding	Orthology	molecular function
magnesium ion binding	Orthology	molecular function
immune system process	Orthology	biological process
protein kinase activity	Orthology	molecular function
protein serine/threonine kinase activity	Orthology	molecular function
calcium ion binding	Blast	molecular function
protein binding	Orthology	molecular function
ATP binding	Orthology	molecular function
extracellular space	Orthology	cellular component
intracellular	Orthology	cellular component
nucleus	Orthology	cellular component
cytoplasm	Orthology	cellular component
mitochondrion	Blast	cellular component
cytosol	Orthology	cellular component
plasma membrane	Orthology	cellular component
protein phosphorylation	Orthology	biological process
signal transduction	Orthology	biological process
membrane	Blast	cellular component
kinase activity	Orthology	molecular function
phosphorylation	Orthology	biological process
transferase activity	Orthology	molecular function
cytokine-mediated signaling pathway	Orthology	biological process
intracellular signal transduction	Orthology	biological process
identical protein binding	Blast	molecular function
protein homodimerization activity	Blast	molecular function
neuron projection	Blast	cellular component
intracellular membrane-bounded organelle	Blast	cellular component
cell body	Blast	cellular component
innate immune response	Orthology	biological process
metal ion binding	Blast	molecular function
protein heterodimerization activity	Blast	molecular function
receptor binding	Orthology	molecular function
cellular response to stress	Orthology	biological process
intracellular organelle part	Orthology	cellular component
whole membrane	Orthology	cellular component
endosome	Orthology	cellular component
bounding membrane of organelle	Orthology	cellular component
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
positive regulation of signal transduction	Orthology	biological process
cell migration	Orthology	biological process
enzyme regulator activity	Blast	molecular function
positive regulation of catalytic activity	Blast	biological process
intracellular non-membrane-bounded organelle	Blast	cellular component
enzyme binding	Blast	molecular function
protein kinase binding	Blast	molecular function
integral component of plasma membrane	Blast	cellular component
macromolecular complex	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
nucleotide binding	Hs	molecular function
magnesium ion binding	Hs	molecular function
cytokine production	Hs	biological process
toll-like receptor signaling pathway	Hs	biological process
immune system process	Hs	biological process
neutrophil mediated immunity	Hs	biological process
MyD88-dependent toll-like receptor signaling pathway	Hs	biological process
protein kinase activity	Hs	molecular function
protein serine/threonine kinase activity	Hs	molecular function
interleukin-1 receptor binding	Hs	molecular function
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
extracellular space	Hs	cellular component
intracellular	Hs	cellular component
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
plasma membrane	Hs	cellular component
protein phosphorylation	Hs	biological process
signal transduction	Hs	biological process
JNK cascade	Hs	biological process
endosome membrane	Hs	cellular component
kinase activity	Hs	molecular function
phosphorylation	Hs	biological process
transferase activity	Hs	molecular function
cytokine-mediated signaling pathway	Hs	biological process
toll-like receptor 9 signaling pathway	Hs	biological process
positive regulation of I-kappaB kinase/NF-kappaB signaling	Hs	biological process
innate immune response	Hs	biological process
positive regulation of NF-kappaB transcription factor activity	Hs	biological process
interleukin-1-mediated signaling pathway	Hs	biological process
neutrophil migration	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	240	1.61e-73
magnesium ion binding	Hs	molecular function	240	1.61e-73
protein kinase activity	Hs	molecular function	240	1.61e-73
protein serine/threonine kinase activity	Hs	molecular function	240	1.61e-73
NF-kappaB-inducing kinase activity	Hs	molecular function	152	1.72e-39
MAP kinase kinase kinase activity	Hs	molecular function	125	1.56e-30
signal transducer activity, downstream of receptor	Hs	molecular function	125	1.56e-30
interleukin-1 receptor binding	Hs	molecular function	240	1.61e-73
calcium ion binding	Hs	molecular function	125	1.56e-30
protein binding	Hs	molecular function	240	1.61e-73
ATP binding	Hs	molecular function	240	1.61e-73
extracellular space	Hs	cellular component	240	1.61e-73
intracellular	Hs	cellular component	240	1.61e-73
nucleus	Hs	cellular component	240	1.61e-73
cytoplasm	Hs	cellular component	240	1.61e-73
mitochondrion	Hs	cellular component	125	1.56e-30
lipid droplet	Hs	cellular component	152	1.72e-39
cytosol	Hs	cellular component	240	1.61e-73
plasma membrane	Hs	cellular component	240	1.61e-73
endosome membrane	Hs	cellular component	240	1.61e-73
membrane	Hs	cellular component	152	1.72e-39
kinase activity	Hs	molecular function	240	1.61e-73
transferase activity	Hs	molecular function	240	1.61e-73
Ras GTPase binding	Hs	molecular function	125	1.56e-30
heat shock protein binding	Hs	molecular function	152	1.72e-39
mitogen-activated protein kinase kinase binding	Hs	molecular function	125	1.56e-30
identical protein binding	Hs	molecular function	125	1.56e-30
protein homodimerization activity	Hs	molecular function	152	1.72e-39
neuron projection	Hs	cellular component	125	1.56e-30
intracellular membrane-bounded organelle	Hs	cellular component	125	1.56e-30
cell body	Hs	cellular component	125	1.56e-30
interleukin-1 receptor complex	Hs	cellular component	152	1.72e-39
metal ion binding	Hs	molecular function	125	1.56e-30
protein heterodimerization activity	Hs	molecular function	152	1.72e-39

GO Term	Analysis	Type	e-value
protein kinase activity	Pfam	molecular function	3.9E-45
protein binding	Pfam	molecular function	1.9E-5
ATP binding	SMART	molecular function	3.2E-30
protein phosphorylation	Pfam	biological process	3.9E-45
signal transduction	Pfam	biological process	1.9E-5