Gene Card
Best human hits
AFG3L2; SPG7; YME1L1
Species
Unique Gene ID
Phmamm.g00004058
Gene Model ID
Phmamm.CG.MTP2014.S140.g04058
Location
S140:193124..197442
Transcript Models and Sequences
AHC0AAA10YB19
Plate: Plate_10_B19
AHC0AAA18YO21
Plate: Plate_18_O21
AHC0AAA2YA19
Plate: Plate_2_A19
AHC0AAA20YN21
Plate: Plate_20_N21
AHC0AAA3YJ03
Plate: Plate_3_J03
AHC0AAA8YE24
Plate: Plate_8_E24
AHC0AAA30YM24
Plate: Plate_30_M24
AHC0AAA33YE22
Plate: Plate_33_E22
AHC0AAA35YF17
Plate: Plate_35_F17
AHC0AAA35YN09
Plate: Plate_35_N09
AHC0AAA36YE22
Plate: Plate_36_E22
AHC0AAA39YB01
Plate: Plate_39_B01
AHC0AAA43YC23
Plate: Plate_43_C23
AHC0AAA59YE01
Plate: Plate_59_E01
AHC0AAA62YD20
Plate: Plate_62_D20
AHC0AAA62YJ06
Plate: Plate_62_J06
AHC0AAA64YL24
Plate: Plate_64_L24
AHC0AAA65YB24
Plate: Plate_65_B24
AHC0AAA70YJ07
Plate: Plate_70_J07
AHC0AAA100YF21
Plate: Plate_100_F21
AHC0AAA101YC13
Plate: Plate_101_C13
AHC0AAA117YK11
Plate: Plate_117_K11
AHC0AAA122YD10
Plate: Plate_122_D10
AHC0AAA124YH20
Plate: Plate_124_H20
AHC0AAA126YG03
Plate: Plate_126_G03
AHC0AAA128YD16
Plate: Plate_128_D16
AHC0AAA128YK15
Plate: Plate_128_K15
AHC0AAA131YH02
Plate: Plate_131_H02
AHC0AAA133YP20
Plate: Plate_133_P20
AHC0AAA136YK18
Plate: Plate_136_K18
AHC0AAA144YO20
Plate: Plate_144_O20
AHC0AAA145YI24
Plate: Plate_145_I24
AHC0AAA148YH24
Plate: Plate_148_H24
AHC0AAA152YC01
Plate: Plate_152_C01
AHC0AAA155YA07
Plate: Plate_155_A07
AHC0AAA90YF18
Plate: Plate_90_F18
AHC0AAA133YP18
Plate: Plate_133_P18
AHC0AAA158YE23
Plate: Plate_158_E23
AHC0AAA160YH11
Plate: Plate_160_H11
AHC0AAA162YM21
Plate: Plate_162_M21
AHC0AAA165YA08
Plate: Plate_165_A08
AHC0AAA171YM18
Plate: Plate_171_M18
AHC0AAA173YJ14
Plate: Plate_173_J14
AHC0AAA175YG07
Plate: Plate_175_G07
AHC0AAA176YB02
Plate: Plate_176_B02
AHC0AAA184YC18
Plate: Plate_184_C18
AHC0AAA185YD04
Plate: Plate_185_D04
AHC0AAA189YN12
Plate: Plate_189_N12
AHC0AAA191YB23
Plate: Plate_191_B23
AHC0AAA200YO06
Plate: Plate_200_O06
AHC0AAA209YL15
Plate: Plate_209_L15
AHC0AAA227YC16
Plate: Plate_227_C16
AHC0AAA228YO16
Plate: Plate_228_O16
AHC0AAA230YC19
Plate: Plate_230_C19
AHC0AAA230YJ20
Plate: Plate_230_J20
AHC0AAA250YA14
Plate: Plate_250_A14
AHC0AAA262YO06
Plate: Plate_262_O06
AHC0AAA268YM01
Plate: Plate_268_M01
AHC0AAA39YD03
Plate: Plate_39_D03
n/a
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IPR Term | Analysis | Definition |
---|---|---|
AAA+_ATPase | SMART | AAA+ ATPase domain |
P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
Peptidase_M41 | Pfam | Peptidase M41 |
ATPase_AAA_CS | ProSitePatterns | ATPase, AAA-type, conserved site |
FtsH | TIGRFAM | Peptidase, FtsH |
ATPase_AAA_core | Pfam | ATPase, AAA-type, core |
Peptidase_M41-like | SUPERFAMILY | Peptidase M41-like |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
metalloendopeptidase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
mitochondrion | Orthology | cellular component |
mitochondrial inner membrane | Orthology | cellular component |
proteolysis | Orthology | biological process |
peptidase activity | Orthology | molecular function |
metallopeptidase activity | Orthology | molecular function |
zinc ion binding | Blast | molecular function |
cell proliferation | Orthology | biological process |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
nuclear body | Orthology | cellular component |
hydrolase activity | Orthology | molecular function |
negative regulation of apoptotic process | Orthology | biological process |
metal ion binding | Orthology | molecular function |
unfolded protein binding | Blast | molecular function |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
nucleoside-triphosphatase activity | Orthology | molecular function |
metal ion transport | Orthology | biological process |
transmembrane transport | Orthology | biological process |
organelle organization | Orthology | biological process |
protein oligomerization | Orthology | biological process |
macromolecular complex | Blast | cellular component |
mitochondrial envelope | Blast | cellular component |
cytoplasmic part | Blast | cellular component |
cell projection part | Blast | cellular component |
axon | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
ATP-dependent peptidase activity | Hs | molecular function |
metalloendopeptidase activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
mitochondrion | Hs | cellular component |
mitochondrial inner membrane | Hs | cellular component |
proteolysis | Hs | biological process |
protein quality control for misfolded or incompletely synthesized proteins | Hs | biological process |
mitochondrial calcium ion transmembrane transport | Hs | biological process |
mitochondrion organization | Hs | biological process |
peptidase activity | Hs | molecular function |
metallopeptidase activity | Hs | molecular function |
cell proliferation | Hs | biological process |
membrane | Hs | cellular component |
integral component of membrane | Hs | cellular component |
nuclear body | Hs | cellular component |
hydrolase activity | Hs | molecular function |
protein hexamerization | Hs | biological process |
mitochondrial protein catabolic process | Hs | biological process |
negative regulation of apoptotic process | Hs | biological process |
metal ion binding | Hs | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 489 | 9.28e-167 |
ATP-dependent peptidase activity | Hs | molecular function | 489 | 9.28e-167 |
metalloendopeptidase activity | Hs | molecular function | 489 | 9.28e-167 |
protein binding | Hs | molecular function | 489 | 9.28e-167 |
ATP binding | Hs | molecular function | 489 | 9.28e-167 |
mitochondrion | Hs | cellular component | 489 | 9.28e-167 |
mitochondrial inner membrane | Hs | cellular component | 489 | 9.28e-167 |
m-AAA complex | Hs | cellular component | 340 | 1.35e-108 |
mitochondrial permeability transition pore complex | Hs | cellular component | 310 | 3.08e-97 |
peptidase activity | Hs | molecular function | 489 | 9.28e-167 |
metallopeptidase activity | Hs | molecular function | 489 | 9.28e-167 |
zinc ion binding | Hs | molecular function | 340 | 1.35e-108 |
membrane | Hs | cellular component | 489 | 9.28e-167 |
integral component of membrane | Hs | cellular component | 489 | 9.28e-167 |
nuclear body | Hs | cellular component | 489 | 9.28e-167 |
hydrolase activity | Hs | molecular function | 489 | 9.28e-167 |
metal ion binding | Hs | molecular function | 489 | 9.28e-167 |
unfolded protein binding | Hs | molecular function | 340 | 1.35e-108 |
axon cytoplasm | Hs | cellular component | 310 | 3.08e-97 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
metalloendopeptidase activity | TIGRFAM | molecular function | 2.7E-158 |
ATP binding | SUPERFAMILY | molecular function | 6.54E-54 |
proteolysis | SUPERFAMILY | biological process | 6.54E-54 |
membrane | TIGRFAM | cellular component | 2.7E-158 |