IPR Term	Analysis	Definition
Selenoprotein_T	PANTHER	Selenoprotein T
Selenoprotein_Rdx-typ	TIGRFAM	Selenoprotein, Rdx-type
Selenoprotein_Rdx-typ	Pfam	Selenoprotein, Rdx-type
Thioredoxin-like_sf	SUPERFAMILY	Thioredoxin-like superfamily

GO Term	Annotation Origin	Type
protein binding	Blast	molecular function
cytoplasm	Blast	cellular component
endoplasmic reticulum	Orthology	cellular component
endoplasmic reticulum membrane	Orthology	cellular component
cytosol	Blast	cellular component
plasma membrane	Blast	cellular component
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
oxidation-reduction process	Orthology	biological process
extracellular exosome	Blast	cellular component
regulation of gene expression	Orthology	biological process
catalytic activity	Orthology	molecular function
cellular process	Orthology	biological process
cell	Orthology	cellular component
binding	Orthology	molecular function
response to organic substance	Orthology	biological process
animal organ development	Orthology	biological process
intrinsic component of plasma membrane	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
selenocysteine incorporation	Hs	biological process
thioredoxin-disulfide reductase activity	Hs	molecular function
endoplasmic reticulum	Hs	cellular component
endoplasmic reticulum membrane	Hs	cellular component
positive regulation of cytosolic calcium ion concentration	Hs	biological process
selenium binding	Hs	molecular function
response to glucose	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
oxidoreductase activity	Hs	molecular function
pancreas development	Hs	biological process
glucose homeostasis	Hs	biological process
cell redox homeostasis	Hs	biological process
oxidation-reduction process	Hs	biological process
cellular oxidant detoxification	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
thioredoxin-disulfide reductase activity	Hs	molecular function	133	4.87e-40
protein binding	Hs	molecular function	34.3	0.008
cytoplasm	Hs	cellular component	34.3	0.008
endoplasmic reticulum	Hs	cellular component	133	4.87e-40
endoplasmic reticulum membrane	Hs	cellular component	133	4.87e-40
cytosol	Hs	cellular component	34.3	0.008
plasma membrane	Hs	cellular component	34.3	0.008
selenium binding	Hs	molecular function	133	4.87e-40
membrane	Hs	cellular component	133	4.87e-40
integral component of membrane	Hs	cellular component	133	4.87e-40
oxidoreductase activity	Hs	molecular function	133	4.87e-40
intrinsic component of the cytoplasmic side of the plasma membrane	Hs	cellular component	34.3	0.008
extracellular exosome	Hs	cellular component	34.3	0.008