Aniseed - Gene card

Gene Card

Best human hits

ISL1; ISL2; LHX9

Species

P.mammillata

Unique Gene ID

Phmamm.g00000576

Gene Model ID

Phmamm.CG.MTP2014.S13.g00576

Location

S13:267283..270762

Transcript Models and Sequences

Phmamm.CG.MTP2014.S13.g00576.01.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

8 results

IPR Term	Analysis	Definition
Homeobox_dom	Pfam	Homeobox domain
Znf_LIM	Pfam	Zinc finger, LIM-type
Homeobox_dom	CDD	Homeobox domain
Znf_LIM	SMART	Zinc finger, LIM-type
Znf_LIM	ProSiteProfiles	Zinc finger, LIM-type
Homeobox-like_sf	SUPERFAMILY	Homeobox-like domain superfamily
Homeobox_dom	SMART	Homeobox domain
Homeobox_dom	ProSiteProfiles	Homeobox domain

GOSlim

55 results

GO Term	Annotation Origin	Type
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Orthology	molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
DNA binding	Orthology	molecular function
chromatin binding	Orthology	molecular function
transcription corepressor activity	Blast	molecular function
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytoplasm	Orthology	cellular component
transcription, DNA-templated	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
regulation of transcription from RNA polymerase II promoter	Orthology	biological process
transcription from RNA polymerase II promoter	Orthology	biological process
multicellular organism development	Orthology	biological process
heart development	Orthology	biological process
positive regulation of cell proliferation	Orthology	biological process
regulation of gene expression	Orthology	biological process
cell differentiation	Orthology	biological process
neuron differentiation	Orthology	biological process
sequence-specific DNA binding	Orthology	molecular function
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
metal ion binding	Orthology	molecular function
neuron development	Orthology	biological process
negative regulation of canonical Wnt signaling pathway	Orthology	biological process
transcription factor binding	Orthology	molecular function
transcription regulatory region sequence-specific DNA binding	Orthology	molecular function
cell migration	Orthology	biological process
cell development	Orthology	biological process
animal organ development	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
receptor binding	Orthology	molecular function
central nervous system development	Orthology	biological process
nervous system development	Orthology	biological process
brain development	Orthology	biological process
axon development	Orthology	biological process
cellular response to stress	Orthology	biological process
response to wounding	Orthology	biological process
axon guidance	Orthology	biological process
protein transport	Orthology	biological process
cell-cell signaling	Orthology	biological process
negative regulation of signal transduction	Orthology	biological process
response to lipid	Orthology	biological process
cellular response to organic substance	Orthology	biological process
organelle organization	Orthology	biological process
cellular protein modification process	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
positive regulation of signal transduction	Orthology	biological process
protein phosphorylation	Orthology	biological process
negative regulation of apoptotic process	Orthology	biological process
angiogenesis	Orthology	biological process
axonogenesis	Orthology	biological process
negative regulation of cell proliferation	Orthology	biological process
defense response	Orthology	biological process
system development	Orthology	biological process

GO (Orthology)

63 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function
RNA polymerase II activating transcription factor binding	Hs	molecular function
RNA polymerase II transcription coactivator activity	Hs	molecular function
enhancer sequence-specific DNA binding	Hs	molecular function
neural crest cell migration	Hs	biological process
heart morphogenesis	Hs	biological process
outflow tract morphogenesis	Hs	biological process
endocardial cushion morphogenesis	Hs	biological process
DNA binding	Hs	molecular function
chromatin binding	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
cytoplasm	Hs	cellular component
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
regulation of transcription from RNA polymerase II promoter	Hs	biological process
transcription from RNA polymerase II promoter	Hs	biological process
multicellular organism development	Hs	biological process
heart development	Hs	biological process
positive regulation of cell proliferation	Hs	biological process
regulation of gene expression	Hs	biological process
positive regulation of vascular endothelial growth factor production	Hs	biological process
positive regulation of epithelial to mesenchymal transition	Hs	biological process
ligand-dependent nuclear receptor binding	Hs	molecular function
spinal cord motor neuron cell fate specification	Hs	biological process
spinal cord motor neuron differentiation	Hs	biological process
trigeminal nerve development	Hs	biological process
pituitary gland development	Hs	biological process
cell differentiation	Hs	biological process
neuron differentiation	Hs	biological process
estrogen receptor binding	Hs	molecular function
pancreas development	Hs	biological process
axon regeneration	Hs	biological process
retinal ganglion cell axon guidance	Hs	biological process
positive regulation of insulin secretion	Hs	biological process
negative regulation of intracellular estrogen receptor signaling pathway	Hs	biological process
positive regulation of histone acetylation	Hs	biological process
positive regulation of tyrosine phosphorylation of STAT protein	Hs	biological process
positive regulation of DNA binding	Hs	biological process
bHLH transcription factor binding	Hs	molecular function
negative regulation of neuron apoptotic process	Hs	biological process
sequence-specific DNA binding	Hs	molecular function
positive regulation of cell differentiation	Hs	biological process
negative regulation of neuron differentiation	Hs	biological process
positive regulation of angiogenesis	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
metal ion binding	Hs	molecular function
neuron fate commitment	Hs	biological process
neuron fate specification	Hs	biological process
neuron development	Hs	biological process
peripheral nervous system neuron development	Hs	biological process
peripheral nervous system neuron axonogenesis	Hs	biological process
negative regulation of epithelial cell proliferation	Hs	biological process
negative regulation of inflammatory response	Hs	biological process
ventricular cardiac muscle tissue morphogenesis	Hs	biological process
pharyngeal system development	Hs	biological process
cellular response to glucocorticoid stimulus	Hs	biological process
negative regulation of canonical Wnt signaling pathway	Hs	biological process
promoter-specific chromatin binding	Hs	molecular function

GO (Blast)

19 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function	278	8.70e-93
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function	278	8.70e-93
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function	278	8.70e-93
RNA polymerase II activating transcription factor binding	Hs	molecular function	278	8.70e-93
RNA polymerase II transcription coactivator activity	Hs	molecular function	278	8.70e-93
enhancer sequence-specific DNA binding	Hs	molecular function	278	8.70e-93
DNA binding	Hs	molecular function	278	8.70e-93
chromatin binding	Hs	molecular function	278	8.70e-93
transcription corepressor activity	Hs	molecular function	97.1	6.96e-23
protein binding	Hs	molecular function	278	8.70e-93
nucleus	Hs	cellular component	278	8.70e-93
nucleoplasm	Hs	cellular component	278	8.70e-93
cytoplasm	Hs	cellular component	278	8.70e-93
ligand-dependent nuclear receptor binding	Hs	molecular function	278	8.70e-93
estrogen receptor binding	Hs	molecular function	278	8.70e-93
bHLH transcription factor binding	Hs	molecular function	278	8.70e-93
sequence-specific DNA binding	Hs	molecular function	278	8.70e-93
metal ion binding	Hs	molecular function	278	8.70e-93
promoter-specific chromatin binding	Hs	molecular function	278	8.70e-93

GO (InterProScan)

1 result

GO Term	Analysis	Type	e-value
DNA binding	SMART	molecular function	1.6E-17