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GENE CARD

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Gene Card

Best human hits

SHMT1; SHMT2

Species

P.fumigata

Unique Gene ID

Phfumi.g00006549

Gene Model ID

Phfumi.CG.MTP2014.S4760.g06549

Location

S4760:2109..4446

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

8 results

IPR Term Analysis Definition
Ser_HO-MeTrfase CDD Serine hydroxymethyltransferase
Ser_HO-MeTrfase Hamap Serine hydroxymethyltransferase
Ser_HO-MeTrfase_PLP_BS ProSitePatterns Serine hydroxymethyltransferase, pyridoxal phosphate binding site
Ser_HO-MeTrfase PIRSF Serine hydroxymethyltransferase
PyrdxlP-dep_Trfase SUPERFAMILY Pyridoxal phosphate-dependent transferase
PyrdxlP-dep_Trfase_major Gene3D Pyridoxal phosphate-dependent transferase, major domain
Ser_HO-MeTrfase PANTHER Serine hydroxymethyltransferase
PyrdxlP-dep_Trfase_dom1 Gene3D Pyridoxal phosphate-dependent transferase domain 1

GOSlim

38 results

GO Term Annotation Origin Type
chromatin binding Blast molecular function
catalytic activity Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
cytoplasm Orthology cellular component
mitochondrion Orthology cellular component
mitochondrial inner membrane Blast cellular component
mitochondrial matrix Blast cellular component
cytosol Orthology cellular component
microtubule cytoskeleton Blast cellular component
membrane Blast cellular component
transferase activity Orthology molecular function
identical protein binding Orthology molecular function
protein homodimerization activity Orthology molecular function
extracellular exosome Orthology cellular component
negative regulation of gene expression Orthology biological process
nucleic acid binding Orthology molecular function
peptidase activity, acting on L-amino acid peptides Orthology molecular function
phosphate-containing compound metabolic process Orthology biological process
cellular metabolic process Orthology biological process
cellular biosynthetic process Orthology biological process
nucleobase-containing compound metabolic process Orthology biological process
small molecule binding Orthology molecular function
anion binding Orthology molecular function
heterocyclic compound binding Orthology molecular function
organic cyclic compound binding Orthology molecular function
coenzyme binding Orthology molecular function
cellular aromatic compound metabolic process Orthology biological process
RNA binding Orthology molecular function
protein oligomerization Orthology biological process
protein homooligomerization Orthology biological process
cation binding Orthology molecular function
mitochondrial envelope Blast cellular component
intracellular organelle lumen Blast cellular component
metabolic process Blast biological process
intracellular non-membrane-bounded organelle Blast cellular component
nuclear part Blast cellular component
macromolecular complex Blast cellular component

GO (Orthology)

33 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
translation repressor activity, nucleic acid binding Hs molecular function
catalytic activity Hs molecular function
glycine hydroxymethyltransferase activity Hs molecular function
thiol-dependent ubiquitin-specific protease activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
cytosol Hs cellular component
dTMP biosynthetic process Hs biological process
glycine metabolic process Hs biological process
glycine biosynthetic process Hs biological process
L-serine metabolic process Hs biological process
one-carbon metabolic process Hs biological process
L-allo-threonine aldolase activity Hs molecular function
purine nucleobase biosynthetic process Hs biological process
protein deubiquitination Hs biological process
amino acid binding Hs molecular function
transferase activity Hs molecular function
negative regulation of translation Hs biological process
glycine biosynthetic process from serine Hs biological process
pyridoxal phosphate binding Hs molecular function
tetrahydrofolate interconversion Hs biological process
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
carnitine biosynthetic process Hs biological process
tetrahydrofolate metabolic process Hs biological process
folic acid metabolic process Hs biological process
mRNA 5'-UTR binding Hs molecular function
protein tetramerization Hs biological process
protein homotetramerization Hs biological process
extracellular exosome Hs cellular component
serine binding Hs molecular function

GO (Blast)

27 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
translation repressor activity, nucleic acid binding Hs molecular function 653 0.0
chromatin binding Hs molecular function 609 0.0
catalytic activity Hs molecular function 653 0.0
glycine hydroxymethyltransferase activity Hs molecular function 653 0.0
thiol-dependent ubiquitin-specific protease activity Hs molecular function 653 0.0
protein binding Hs molecular function 653 0.0
nucleus Hs cellular component 653 0.0
cytoplasm Hs cellular component 653 0.0
mitochondrion Hs cellular component 653 0.0
mitochondrial inner membrane Hs cellular component 609 0.0
mitochondrial intermembrane space Hs cellular component 609 0.0
mitochondrial matrix Hs cellular component 609 0.0
cytosol Hs cellular component 653 0.0
methyltransferase activity Hs molecular function 609 0.0
L-allo-threonine aldolase activity Hs molecular function 653 0.0
microtubule cytoskeleton Hs cellular component 609 0.0
membrane Hs cellular component 609 0.0
amino acid binding Hs molecular function 653 0.0
transferase activity Hs molecular function 653 0.0
pyridoxal phosphate binding Hs molecular function 653 0.0
mitochondrial nucleoid Hs cellular component 609 0.0
identical protein binding Hs molecular function 653 0.0
protein homodimerization activity Hs molecular function 653 0.0
mRNA 5'-UTR binding Hs molecular function 653 0.0
extracellular exosome Hs cellular component 653 0.0
BRISC complex Hs cellular component 609 0.0
serine binding Hs molecular function 653 0.0

GO (InterProScan)

5 results

GO Term Analysis Type e-value
catalytic activity Gene3D molecular function 3.3E-211
glycine hydroxymethyltransferase activity CDD molecular function 0.0
glycine biosynthetic process from serine CDD biological process 0.0
pyridoxal phosphate binding CDD molecular function 0.0
tetrahydrofolate interconversion CDD biological process 0.0