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GENE CARD

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Gene Card

Best human hits

PLG; ROR1; ROR2

Species

P.fumigata

Unique Gene ID

Phfumi.g00001810

Gene Model ID

Phfumi.CG.MTP2014.S345.g01810

Location

S345:21683..33218

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

20 results

IPR Term Analysis Definition
Kringle SMART Kringle
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain
Ig_I-set Pfam Immunoglobulin I-set
Kringle_sf Gene3D Kringle superfamily
Frizzled_dom_sf Gene3D Frizzled cysteine-rich domain superfamily
Ig_sub SMART Immunoglobulin subtype
Ig-like_dom_sf SUPERFAMILY Immunoglobulin-like domain superfamily
Kringle ProSiteProfiles Kringle
Kringle_CS ProSitePatterns Kringle, conserved site
Frizzled_dom ProSiteProfiles Frizzled domain
Ig_sub2 SMART Immunoglobulin subtype 2
Kringle CDD Kringle
Ig-like_fold Gene3D Immunoglobulin-like fold
Ig-like_dom ProSiteProfiles Immunoglobulin-like domain
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site
Frizzled_dom Pfam Frizzled domain
Kringle Pfam Kringle
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Kringle-like SUPERFAMILY Kringle-like fold

GOSlim

74 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
endopeptidase activity Blast molecular function
serine-type endopeptidase activity Blast molecular function
protein kinase activity Orthology molecular function
receptor binding Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
extracellular region Blast cellular component
extracellular space Blast cellular component
cytoplasm Orthology cellular component
microtubule Orthology cellular component
plasma membrane Orthology cellular component
integral component of plasma membrane Orthology cellular component
protein phosphorylation Orthology biological process
signal transduction Orthology biological process
multicellular organism development Orthology biological process
sensory perception of sound Orthology biological process
peptidase activity Blast molecular function
serine-type peptidase activity Blast molecular function
negative regulation of cell proliferation Orthology biological process
cell surface Orthology cellular component
membrane Orthology cellular component
integral component of membrane Orthology cellular component
kinase activity Orthology molecular function
phosphorylation Orthology biological process
transferase activity Orthology molecular function
hydrolase activity Blast molecular function
enzyme binding Blast molecular function
kinase binding Blast molecular function
cell differentiation Orthology biological process
axon Orthology cellular component
cell projection Orthology cellular component
neuronal cell body Orthology cellular component
positive regulation of transcription, DNA-templated Orthology biological process
metal ion binding Orthology molecular function
regulation of canonical Wnt signaling pathway Orthology biological process
extracellular exosome Blast cellular component
negative regulation of canonical Wnt signaling pathway Orthology biological process
positive regulation of canonical Wnt signaling pathway Orthology biological process
system development Orthology biological process
animal organ development Orthology biological process
anatomical structure morphogenesis Orthology biological process
cytoskeletal part Orthology cellular component
anatomical structure formation involved in morphogenesis Orthology biological process
transmembrane signaling receptor activity Orthology molecular function
cell surface receptor signaling pathway Orthology biological process
cell-cell signaling Orthology biological process
cellular response to stress Orthology biological process
intracellular signal transduction Orthology biological process
cell development Orthology biological process
neurogenesis Orthology biological process
central nervous system development Orthology biological process
cell migration Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
cellular response to organic substance Orthology biological process
reproductive process Orthology biological process
whole membrane Orthology cellular component
intracellular organelle part Orthology cellular component
cytoplasmic vesicle Orthology cellular component
bounding membrane of organelle Orthology cellular component
transcription factor activity, sequence-specific DNA binding Orthology molecular function
positive regulation of signal transduction Orthology biological process
macromolecular complex Orthology cellular component
positive regulation of catalytic activity Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
cell projection part Orthology cellular component
synapse part Orthology cellular component
chemical synaptic transmission Orthology biological process
signaling receptor activity Orthology molecular function
immune system process Orthology biological process
endomembrane system Blast cellular component
intracellular organelle lumen Blast cellular component
plasma membrane part Blast cellular component
macromolecular complex binding Blast molecular function

GO (Orthology)

64 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
nucleotide binding Hs molecular function
skeletal system development Hs biological process
cartilage condensation Hs biological process
stress fiber Hs cellular component
somitogenesis Hs biological process
protein kinase activity Hs molecular function
protein tyrosine kinase activity Hs molecular function
transmembrane receptor protein tyrosine kinase activity Hs molecular function
frizzled binding Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
cytoplasm Hs cellular component
microtubule Hs cellular component
plasma membrane Hs cellular component
integral component of plasma membrane Hs cellular component
protein phosphorylation Hs biological process
signal transduction Hs biological process
transmembrane receptor protein tyrosine kinase signaling pathway Hs biological process
Wnt signaling pathway, calcium modulating pathway Hs biological process
smoothened signaling pathway Hs biological process
JNK cascade Hs biological process
multicellular organism development Hs biological process
sensory perception of sound Hs biological process
negative regulation of cell proliferation Hs biological process
cell surface Hs cellular component
astrocyte development Hs biological process
membrane Hs cellular component
integral component of membrane Hs cellular component
Wnt signaling pathway Hs biological process
kinase activity Hs molecular function
phosphorylation Hs biological process
transferase activity Hs molecular function
Wnt-protein binding Hs molecular function
peptidyl-tyrosine phosphorylation Hs biological process
cell differentiation Hs biological process
bone mineralization Hs biological process
positive regulation of cell migration Hs biological process
axon Hs cellular component
dendrite Hs cellular component
BMP signaling pathway Hs biological process
embryonic genitalia morphogenesis Hs biological process
male genitalia development Hs biological process
clathrin-coated endocytic vesicle membrane Hs cellular component
inner ear morphogenesis Hs biological process
Wnt-activated receptor activity Hs molecular function
cell projection Hs cellular component
neuronal cell body Hs cellular component
positive regulation of I-kappaB kinase/NF-kappaB signaling Hs biological process
receptor complex Hs cellular component
positive regulation of JUN kinase activity Hs biological process
axon terminus Hs cellular component
cell fate commitment Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
metal ion binding Hs molecular function
inner ear development Hs biological process
positive regulation of NF-kappaB transcription factor activity Hs biological process
positive regulation of synaptic transmission, glutamatergic Hs biological process
Wnt signaling pathway, planar cell polarity pathway Hs biological process
SMAD protein signal transduction Hs biological process
regulation of canonical Wnt signaling pathway Hs biological process
negative regulation of canonical Wnt signaling pathway Hs biological process
positive regulation of canonical Wnt signaling pathway Hs biological process
coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway Hs molecular function
macrophage migration Hs biological process

GO (Blast)

48 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 293 8.74e-89
stress fiber Hs cellular component 276 9.79e-83
endopeptidase activity Hs molecular function 61.2 9.22e-10
serine-type endopeptidase activity Hs molecular function 61.2 9.22e-10
protein kinase activity Hs molecular function 293 8.74e-89
protein tyrosine kinase activity Hs molecular function 293 8.74e-89
transmembrane receptor protein tyrosine kinase activity Hs molecular function 293 8.74e-89
receptor binding Hs molecular function 61.2 9.22e-10
frizzled binding Hs molecular function 293 8.74e-89
protein binding Hs molecular function 293 8.74e-89
ATP binding Hs molecular function 293 8.74e-89
extracellular region Hs cellular component 61.2 9.22e-10
extracellular space Hs cellular component 61.2 9.22e-10
cytoplasm Hs cellular component 293 8.74e-89
microtubule Hs cellular component 293 8.74e-89
plasma membrane Hs cellular component 293 8.74e-89
integral component of plasma membrane Hs cellular component 293 8.74e-89
peptidase activity Hs molecular function 61.2 9.22e-10
serine-type peptidase activity Hs molecular function 61.2 9.22e-10
cell surface Hs cellular component 293 8.74e-89
membrane Hs cellular component 293 8.74e-89
integral component of membrane Hs cellular component 293 8.74e-89
kinase activity Hs molecular function 293 8.74e-89
transferase activity Hs molecular function 293 8.74e-89
hydrolase activity Hs molecular function 61.2 9.22e-10
Wnt-protein binding Hs molecular function 293 8.74e-89
enzyme binding Hs molecular function 61.2 9.22e-10
kinase binding Hs molecular function 61.2 9.22e-10
protein domain specific binding Hs molecular function 61.2 9.22e-10
axon Hs cellular component 276 9.79e-83
dendrite Hs cellular component 293 8.74e-89
clathrin-coated endocytic vesicle membrane Hs cellular component 293 8.74e-89
platelet alpha granule lumen Hs cellular component 61.2 9.22e-10
extrinsic component of external side of plasma membrane Hs cellular component 61.2 9.22e-10
apolipoprotein binding Hs molecular function 61.2 9.22e-10
Wnt-activated receptor activity Hs molecular function 276 9.79e-83
cell projection Hs cellular component 276 9.79e-83
neuronal cell body Hs cellular component 293 8.74e-89
receptor complex Hs cellular component 276 9.79e-83
axon terminus Hs cellular component 276 9.79e-83
other organism cell membrane Hs cellular component 61.2 9.22e-10
metal ion binding Hs molecular function 293 8.74e-89
chaperone binding Hs molecular function 61.2 9.22e-10
extracellular exosome Hs cellular component 61.2 9.22e-10
blood microparticle Hs cellular component 61.2 9.22e-10
proteasome core complex binding Hs molecular function 61.2 9.22e-10
coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway Hs molecular function 293 8.74e-89
protein antigen binding Hs molecular function 61.2 9.22e-10

GO (InterProScan)

4 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 3.6E-9
protein binding Gene3D molecular function 1.6E-24
ATP binding ProSiteProfiles molecular function 11.425
protein phosphorylation Pfam biological process 3.6E-9