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GENE CARD

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Gene Card

Best human hits

EZR; MSN; RDX

Species

P.fumigata

Unique Gene ID

Phfumi.g00000022

Gene Model ID

Phfumi.CG.MTP2014.S1.g00022

Location

S1:507210..520222

Transcript Models and Sequences

  Phfumi.CG.MTP2014.S1.g00022.01.t
Phfumi.CG.MTP2014.S1.g00022.02.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

18 results

IPR Term Analysis Definition
FERM_central Pfam FERM central domain
FERM_PH-like_C SMART FERM, C-terminal PH-like domain
FERM_central CDD FERM central domain
FERM_CS ProSitePatterns FERM conserved site
ERM_C_dom Pfam Ezrin/radixin/moesin, C-terminal
Ubiquitin-like_domsf SUPERFAMILY Ubiquitin-like domain superfamily
FERM_2 SUPERFAMILY FERM superfamily, second domain
Moesin_tail_sf Gene3D Moesin tail domain superfamily
FERM_PH-like_C Pfam FERM, C-terminal PH-like domain
PH-like_dom_sf Gene3D PH-like domain superfamily
Ez/rad/moesin-like PRINTS Ezrin/radixin/moesin-like
FERM_domain ProSiteProfiles FERM domain
Moesin_tail_sf SUPERFAMILY Moesin tail domain superfamily
Band_41_domain PRINTS Band 4.1 domain
FERM_N Pfam FERM, N-terminal
ERM PIRSF Ezrin/radixin/moesin
FERM/acyl-CoA-bd_prot_sf Gene3D FERM/acyl-CoA-binding protein superfamily
Band_41_domain SMART Band 4.1 domain

GOSlim

88 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
RNA binding Orthology molecular function
actin binding Orthology molecular function
receptor binding Orthology molecular function
protein binding Orthology molecular function
extracellular space Orthology cellular component
intracellular Orthology cellular component
nucleus Orthology cellular component
cytoplasm Orthology cellular component
endosome Orthology cellular component
cytosol Orthology cellular component
cytoskeleton Orthology cellular component
plasma membrane Orthology cellular component
brush border Orthology cellular component
focal adhesion Orthology cellular component
axon guidance Orthology biological process
microtubule binding Orthology molecular function
protein C-terminus binding Orthology molecular function
cytoskeletal protein binding Orthology molecular function
cell surface Orthology cellular component
positive regulation of gene expression Orthology biological process
membrane Orthology cellular component
basolateral plasma membrane Orthology cellular component
apical plasma membrane Orthology cellular component
enzyme binding Orthology molecular function
protein kinase binding Orthology molecular function
lamellipodium Orthology cellular component
midbody Orthology cellular component
vesicle Orthology cellular component
macromolecular complex Orthology cellular component
identical protein binding Orthology molecular function
protein homodimerization activity Orthology molecular function
cell projection Orthology cellular component
regulation of GTPase activity Orthology biological process
myelin sheath Orthology cellular component
cell body Orthology cellular component
membrane raft Orthology cellular component
apical part of cell Orthology cellular component
establishment of protein localization Orthology biological process
perinuclear region of cytoplasm Orthology cellular component
cell adhesion molecule binding Orthology molecular function
actin filament binding Orthology molecular function
extracellular exosome Orthology cellular component
cell periphery Orthology cellular component
nucleolus Orthology cellular component
plasma membrane region Orthology cellular component
cell leading edge Orthology cellular component
plasma membrane part Orthology cellular component
G-protein coupled receptor signaling pathway Orthology biological process
organelle organization Orthology biological process
structural molecule activity Orthology molecular function
cytoskeletal part Orthology cellular component
adherens junction Orthology cellular component
cytoplasmic part Orthology cellular component
cell Orthology cellular component
cellular protein localization Orthology biological process
cell morphogenesis Orthology biological process
cellular component organization Orthology biological process
intracellular signal transduction Orthology biological process
membrane part Orthology cellular component
cell projection assembly Orthology biological process
cell migration Orthology biological process
anatomical structure development Orthology biological process
cell differentiation Orthology biological process
microtubule-based process Orthology biological process
cell projection membrane Orthology cellular component
membrane organization Orthology biological process
neuron projection Orthology cellular component
cluster of actin-based cell projections Orthology cellular component
small GTPase mediated signal transduction Orthology biological process
regulation of signal transduction Orthology biological process
cell adhesion Orthology biological process
cellular process Orthology biological process
cell projection part Orthology cellular component
microtubule organizing center Orthology cellular component
developmental process Orthology biological process
protein localization Orthology biological process
anatomical structure morphogenesis Orthology biological process
protein transport Orthology biological process
cell surface receptor signaling pathway Orthology biological process
immune response Orthology biological process
negative regulation of signal transduction Orthology biological process
immune system process Orthology biological process
cell part Orthology cellular component
cell development Orthology biological process
protein phosphorylation Orthology biological process
protein localization to membrane Orthology biological process
G1/S transition of mitotic cell cycle Orthology biological process

GO (Orthology)

122 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
fibrillar center Hs cellular component
ruffle Hs cellular component
immunological synapse Hs cellular component
uropod Hs cellular component
sphingosine-1-phosphate signaling pathway Hs biological process
RNA binding Hs molecular function
double-stranded RNA binding Hs molecular function
actin binding Hs molecular function
receptor binding Hs molecular function
structural constituent of cytoskeleton Hs molecular function
protein binding Hs molecular function
extracellular space Hs cellular component
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
endosome Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
actin filament Hs cellular component
plasma membrane Hs cellular component
microvillus Hs cellular component
brush border Hs cellular component
cell-cell adherens junction Hs cellular component
focal adhesion Hs cellular component
cell cortex Hs cellular component
cytoskeleton organization Hs biological process
cytoskeletal anchoring at plasma membrane Hs biological process
axon guidance Hs biological process
microtubule binding Hs molecular function
protein C-terminus binding Hs molecular function
cytoskeletal protein binding Hs molecular function
regulation of cell shape Hs biological process
regulation of cell size Hs biological process
cell surface Hs cellular component
positive regulation of gene expression Hs biological process
protein kinase A signaling Hs biological process
actin cytoskeleton Hs cellular component
membrane Hs cellular component
basolateral plasma membrane Hs cellular component
apical plasma membrane Hs cellular component
extrinsic component of membrane Hs cellular component
enzyme binding Hs molecular function
protein kinase binding Hs molecular function
protein domain specific binding Hs molecular function
lamellipodium Hs cellular component
microvillus assembly Hs biological process
filopodium Hs cellular component
T-tubule Hs cellular component
positive regulation of cell migration Hs biological process
midbody Hs cellular component
epithelial cell differentiation Hs biological process
cortical cytoskeleton Hs cellular component
cortical actin cytoskeleton Hs cellular component
astral microtubule organization Hs biological process
pseudopodium Hs cellular component
microvillus membrane Hs cellular component
actin cytoskeleton reorganization Hs biological process
receptor internalization Hs biological process
vesicle Hs cellular component
cleavage furrow Hs cellular component
regulation of actin filament bundle assembly Hs biological process
stereocilium Hs cellular component
regulation of Rap protein signal transduction Hs biological process
ruffle membrane Hs cellular component
macromolecular complex Hs cellular component
negative regulation of homotypic cell-cell adhesion Hs biological process
protein kinase A catalytic subunit binding Hs molecular function
protein kinase A regulatory subunit binding Hs molecular function
negative regulation of GTPase activity Hs biological process
cellular protein complex localization Hs biological process
establishment or maintenance of apical/basal cell polarity Hs biological process
ciliary basal body Hs cellular component
positive regulation of multicellular organism growth Hs biological process
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
cell projection Hs cellular component
regulation of GTPase activity Hs biological process
myelin sheath Hs cellular component
cortical microtubule organization Hs biological process
cell body Hs cellular component
microspike Hs cellular component
S100 protein binding Hs molecular function
plasma membrane raft Hs cellular component
membrane raft Hs cellular component
apical protein localization Hs biological process
apical part of cell Hs cellular component
establishment of protein localization Hs biological process
establishment of epithelial cell apical/basal polarity Hs biological process
cadherin binding Hs molecular function
negative regulation of cell size Hs biological process
filopodium assembly Hs biological process
phosphatidylinositol-mediated signaling Hs biological process
perinuclear region of cytoplasm Hs cellular component
positive regulation of protein secretion Hs biological process
cell adhesion molecule binding Hs molecular function
negative regulation of T cell receptor signaling pathway Hs biological process
leukocyte migration Hs biological process
actin filament binding Hs molecular function
barbed-end actin filament capping Hs biological process
actin filament bundle assembly Hs biological process
protein kinase A binding Hs molecular function
ATPase binding Hs molecular function
cell tip Hs cellular component
establishment of centrosome localization Hs biological process
actin filament capping Hs biological process
establishment of endothelial barrier Hs biological process
extracellular exosome Hs cellular component
negative regulation of ERK1 and ERK2 cascade Hs biological process
invadopodium Hs cellular component
cell periphery Hs cellular component
blood microparticle Hs cellular component
protein localization to plasma membrane Hs biological process
protein localization to cell cortex Hs biological process
astrocyte projection Hs cellular component
Schwann cell microvillus Hs cellular component
disordered domain specific binding Hs molecular function
cytoplasmic side of apical plasma membrane Hs cellular component
positive regulation of G1/S transition of mitotic cell cycle Hs biological process
positive regulation of protein localization to plasma membrane Hs biological process
positive regulation of cellular protein catabolic process Hs biological process
negative regulation of adherens junction organization Hs biological process

GO (Blast)

77 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
fibrillar center Hs cellular component 687 0.0
ruffle Hs cellular component 696 0.0
immunological synapse Hs cellular component 687 0.0
uropod Hs cellular component 687 0.0
RNA binding Hs molecular function 696 0.0
double-stranded RNA binding Hs molecular function 686 0.0
actin binding Hs molecular function 696 0.0
receptor binding Hs molecular function 686 0.0
structural constituent of cytoskeleton Hs molecular function 686 0.0
protein binding Hs molecular function 696 0.0
extracellular space Hs cellular component 696 0.0
intracellular Hs cellular component 687 0.0
nucleus Hs cellular component 686 0.0
cytoplasm Hs cellular component 696 0.0
endosome Hs cellular component 687 0.0
cytosol Hs cellular component 687 0.0
cytoskeleton Hs cellular component 696 0.0
actin filament Hs cellular component 687 0.0
plasma membrane Hs cellular component 696 0.0
microvillus Hs cellular component 696 0.0
brush border Hs cellular component 687 0.0
cell-cell adherens junction Hs cellular component 696 0.0
focal adhesion Hs cellular component 696 0.0
cell cortex Hs cellular component 687 0.0
microtubule binding Hs molecular function 687 0.0
protein C-terminus binding Hs molecular function 687 0.0
cytoskeletal protein binding Hs molecular function 696 0.0
cell surface Hs cellular component 686 0.0
actin cytoskeleton Hs cellular component 687 0.0
membrane Hs cellular component 696 0.0
basolateral plasma membrane Hs cellular component 687 0.0
apical plasma membrane Hs cellular component 696 0.0
extrinsic component of membrane Hs cellular component 687 0.0
enzyme binding Hs molecular function 686 0.0
protein kinase binding Hs molecular function 686 0.0
protein domain specific binding Hs molecular function 696 0.0
lamellipodium Hs cellular component 696 0.0
filopodium Hs cellular component 696 0.0
T-tubule Hs cellular component 696 0.0
midbody Hs cellular component 696 0.0
cortical cytoskeleton Hs cellular component 687 0.0
cortical actin cytoskeleton Hs cellular component 696 0.0
pseudopodium Hs cellular component 686 0.0
microvillus membrane Hs cellular component 687 0.0
vesicle Hs cellular component 687 0.0
cleavage furrow Hs cellular component 696 0.0
stereocilium Hs cellular component 696 0.0
ruffle membrane Hs cellular component 687 0.0
macromolecular complex Hs cellular component 687 0.0
protein kinase A catalytic subunit binding Hs molecular function 687 0.0
protein kinase A regulatory subunit binding Hs molecular function 687 0.0
ciliary basal body Hs cellular component 687 0.0
identical protein binding Hs molecular function 687 0.0
protein homodimerization activity Hs molecular function 696 0.0
cell projection Hs cellular component 696 0.0
myelin sheath Hs cellular component 696 0.0
cell body Hs cellular component 687 0.0
microspike Hs cellular component 687 0.0
S100 protein binding Hs molecular function 687 0.0
plasma membrane raft Hs cellular component 687 0.0
membrane raft Hs cellular component 687 0.0
apical part of cell Hs cellular component 696 0.0
cadherin binding Hs molecular function 696 0.0
perinuclear region of cytoplasm Hs cellular component 687 0.0
cell adhesion molecule binding Hs molecular function 687 0.0
actin filament binding Hs molecular function 687 0.0
protein kinase A binding Hs molecular function 696 0.0
ATPase binding Hs molecular function 696 0.0
cell tip Hs cellular component 696 0.0
extracellular exosome Hs cellular component 696 0.0
invadopodium Hs cellular component 687 0.0
cell periphery Hs cellular component 696 0.0
blood microparticle Hs cellular component 686 0.0
astrocyte projection Hs cellular component 687 0.0
Schwann cell microvillus Hs cellular component 687 0.0
disordered domain specific binding Hs molecular function 687 0.0
cytoplasmic side of apical plasma membrane Hs cellular component 687 0.0

GO (InterProScan)

3 results

GO Term Analysis Type e-value
actin binding PIRSF molecular function 1.6E-258
cytoskeleton ProSiteProfiles cellular component 80.594
cytoskeletal protein binding PRINTS molecular function 2.5E-81

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