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Gene Card

Best human hits

EDARADD; MYD88; UNC5CL

Species

M.oculata

Unique Gene ID

Moocul.g00005330

Gene Model ID

Moocul.CG.ELv1_2.S75562.g05330

Location

S75562:175429..181852

Transcript Models and Sequences

  Moocul.CG.ELv1_2.S75562.g05330.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
TIR_dom Pfam Toll/interleukin-1 receptor homology (TIR) domain
DEATH-like_dom_sf SUPERFAMILY Death-like domain superfamily
TIR_dom ProSiteProfiles Toll/interleukin-1 receptor homology (TIR) domain
Toll_tir_struct_dom_sf SUPERFAMILY Toll/interleukin-1 receptor homology (TIR) domain superfamily
Death_domain Pfam Death domain
Toll_tir_struct_dom_sf Gene3D Toll/interleukin-1 receptor homology (TIR) domain superfamily
Death_domain ProSiteProfiles Death domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

48 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
toll-like receptor signaling pathway Hs biological process
immune system process Hs biological process
MyD88-dependent toll-like receptor signaling pathway Hs biological process
receptor binding Hs molecular function
Toll binding Hs molecular function
death receptor binding Hs molecular function
interleukin-1 receptor binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
apoptotic process Hs biological process
inflammatory response Hs biological process
signal transduction Hs biological process
cell surface receptor signaling pathway Hs biological process
JNK cascade Hs biological process
Toll signaling pathway Hs biological process
response to virus Hs biological process
endosome membrane Hs cellular component
regulation of gene expression Hs biological process
positive regulation of gene expression Hs biological process
postsynaptic density Hs cellular component
immunoglobulin mediated immune response Hs biological process
cytokine-mediated signaling pathway Hs biological process
lipopolysaccharide-mediated signaling pathway Hs biological process
positive regulation of type I interferon production Hs biological process
response to peptidoglycan Hs biological process
response to lipopolysaccharide Hs biological process
toll-like receptor 9 signaling pathway Hs biological process
Toll-like receptor binding Hs molecular function
regulation of cell proliferation Hs biological process
identical protein binding Hs molecular function
negative regulation of apoptotic process Hs biological process
positive regulation of I-kappaB kinase/NF-kappaB signaling Hs biological process
protein self-association Hs molecular function
negative regulation of growth of symbiont in host Hs biological process
innate immune response Hs biological process
positive regulation of JNK cascade Hs biological process
regulation of inflammatory response Hs biological process
defense response to Gram-positive bacterium Hs biological process
positive regulation of NF-kappaB transcription factor activity Hs biological process
interleukin-1-mediated signaling pathway Hs biological process
3'-UTR-mediated mRNA stabilization Hs biological process
TIR domain binding Hs molecular function
cellular response to mechanical stimulus Hs biological process
establishment of endothelial intestinal barrier Hs biological process
regulation of neutrophil migration Hs biological process

GO (Blast)

19 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
netrin receptor activity Hs molecular function 42.0 5.01e-04
receptor binding Hs molecular function 79.0 3.07e-16
Toll binding Hs molecular function 79.0 3.07e-16
death receptor binding Hs molecular function 79.0 3.07e-16
interleukin-1 receptor binding Hs molecular function 79.0 3.07e-16
protein binding Hs molecular function 79.0 3.07e-16
nucleus Hs cellular component 79.0 3.07e-16
cytoplasm Hs cellular component 79.0 3.07e-16
cytosol Hs cellular component 79.0 3.07e-16
plasma membrane Hs cellular component 79.0 3.07e-16
peptidase activity Hs molecular function 42.0 5.01e-04
endosome membrane Hs cellular component 79.0 3.07e-16
postsynaptic density Hs cellular component 79.0 3.07e-16
membrane Hs cellular component 42.0 5.01e-04
integral component of membrane Hs cellular component 42.0 5.01e-04
Toll-like receptor binding Hs molecular function 79.0 3.07e-16
identical protein binding Hs molecular function 79.0 3.07e-16
protein self-association Hs molecular function 79.0 3.07e-16
TIR domain binding Hs molecular function 79.0 3.07e-16

GO (InterProScan)

2 results

GO Term Analysis Type e-value
protein binding Pfam molecular function 8.5E-8
signal transduction Pfam biological process 8.5E-8

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