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GENE CARD

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Gene Card

Best human hits

USP40; USP47; USP7

Species

H.roretzi

Unique Gene ID

Harore.g00013041

Gene Model ID

Harore.CG.MTP2014.S398.g13041

Location

S398:11777..46586

Transcript Models and Sequences

  Harore.CG.MTP2014.S398.g13041.01.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

3 results

IPR Term Analysis Definition
USP_dom ProSiteProfiles Ubiquitin specific protease domain
USP_CS ProSitePatterns Ubiquitin specific protease, conserved site
Peptidase_C19_UCH Pfam Peptidase C19, ubiquitin carboxyl-terminal hydrolase

GOSlim

26 results

GO Term Annotation Origin Type
protein binding Orthology molecular function
nucleus Blast cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
cytosol Blast cellular component
DNA repair Orthology biological process
proteolysis Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
protein C-terminus binding Blast molecular function
transcription factor binding Blast molecular function
peptidase activity Orthology molecular function
nuclear body Blast cellular component
hydrolase activity Orthology molecular function
ubiquitin protein ligase binding Blast molecular function
macromolecular complex Orthology cellular component
negative regulation of apoptotic process Orthology biological process
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of canonical Wnt signaling pathway Orthology biological process
peptidase activity, acting on L-amino acid peptides Orthology molecular function
G2/M transition of mitotic cell cycle Orthology biological process
intracellular part Orthology cellular component
cellular component organization Orthology biological process
endopeptidase activity Orthology molecular function
intracellular signal transduction Orthology biological process
negative regulation of signal transduction Orthology biological process
intracellular non-membrane-bounded organelle Blast cellular component

GO (Orthology)

26 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
thiol-dependent ubiquitin-specific protease activity Hs molecular function
protein binding Hs molecular function
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
DNA repair Hs biological process
base-excision repair Hs biological process
proteolysis Hs biological process
ubiquitin-dependent protein catabolic process Hs biological process
cellular response to DNA damage stimulus Hs biological process
peptidase activity Hs molecular function
cysteine-type peptidase activity Hs molecular function
negative regulation of G2/M transition of mitotic cell cycle Hs biological process
protein deubiquitination Hs biological process
hydrolase activity Hs molecular function
SCF ubiquitin ligase complex Hs cellular component
positive regulation of cell growth Hs biological process
cellular response to UV Hs biological process
thiol-dependent ubiquitinyl hydrolase activity Hs molecular function
response to drug Hs biological process
negative regulation of apoptotic process Hs biological process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
WD40-repeat domain binding Hs molecular function
positive regulation of canonical Wnt signaling pathway Hs biological process
ubiquitinyl hydrolase activity Hs molecular function
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Hs biological process

GO (Blast)

23 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
p53 binding Hs molecular function 191 6.27e-49
cysteine-type endopeptidase activity Hs molecular function 191 6.27e-49
thiol-dependent ubiquitin-specific protease activity Hs molecular function 677 0.0
protein binding Hs molecular function 677 0.0
nucleus Hs cellular component 191 6.27e-49
nucleoplasm Hs cellular component 677 0.0
chromosome Hs cellular component 191 6.27e-49
cytoplasm Hs cellular component 677 0.0
cytosol Hs cellular component 191 6.27e-49
protein C-terminus binding Hs molecular function 191 6.27e-49
transcription factor binding Hs molecular function 191 6.27e-49
peptidase activity Hs molecular function 677 0.0
cysteine-type peptidase activity Hs molecular function 677 0.0
nuclear body Hs cellular component 191 6.27e-49
PML body Hs cellular component 191 6.27e-49
hydrolase activity Hs molecular function 677 0.0
SCF ubiquitin ligase complex Hs cellular component 677 0.0
ubiquitin protein ligase binding Hs molecular function 191 6.27e-49
macromolecular complex Hs cellular component 191 6.27e-49
thiol-dependent ubiquitinyl hydrolase activity Hs molecular function 677 0.0
WD40-repeat domain binding Hs molecular function 677 0.0
ubiquitinyl hydrolase activity Hs molecular function 677 0.0
Lys48-specific deubiquitinase activity Hs molecular function 191 6.27e-49

GO (InterProScan)

3 results

GO Term Analysis Type e-value
ubiquitin-dependent protein catabolic process ProSitePatterns biological process
protein deubiquitination Pfam biological process 1.1E-47
thiol-dependent ubiquitinyl hydrolase activity Pfam molecular function 1.1E-47