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GENE CARD

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Gene Card

Best human hits

ADAMTS14; ADAMTS2; ADAMTS3

Species

H.roretzi

Unique Gene ID

Harore.g00012947

Gene Model ID

Harore.CG.MTP2014.S7.g12947

Location

S7:86854..102980

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

11 results

IPR Term Analysis Definition
TSP1_rpt_sf SUPERFAMILY Thrombospondin type-1 (TSP1) repeat superfamily
PLAC ProSiteProfiles PLAC
TSP1_rpt_sf Gene3D Thrombospondin type-1 (TSP1) repeat superfamily
Peptidase_M12B ProSiteProfiles Peptidase M12B, ADAM/reprolysin
TSP1_rpt ProSiteProfiles Thrombospondin type-1 (TSP1) repeat
Peptidase_M12B Pfam Peptidase M12B, ADAM/reprolysin
MetalloPept_cat_dom_sf Gene3D Metallopeptidase, catalytic domain superfamily
ADAM_spacer1 Pfam ADAM-TS Spacer 1
TSP1_rpt Pfam Thrombospondin type-1 (TSP1) repeat
TSP1_rpt SMART Thrombospondin type-1 (TSP1) repeat
Peptidase_M12B_N Pfam Peptidase M12B, propeptide

GOSlim

25 results

GO Term Annotation Origin Type
endopeptidase activity Orthology molecular function
metalloendopeptidase activity Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
proteolysis Orthology biological process
spermatogenesis Orthology biological process
peptidase activity Orthology molecular function
metallopeptidase activity Orthology molecular function
zinc ion binding Orthology molecular function
hydrolase activity Orthology molecular function
metal ion binding Orthology molecular function
extracellular exosome Orthology cellular component
anion binding Orthology molecular function
carbohydrate derivative binding Orthology molecular function
gene expression Orthology biological process
extracellular matrix organization Orthology biological process
animal organ development Orthology biological process
catabolic process Orthology biological process
extracellular region part Orthology cellular component
biosynthetic process Orthology biological process
cellular component organization Orthology biological process
cell surface receptor signaling pathway Orthology biological process
positive regulation of signal transduction Orthology biological process
cellular response to organic substance Orthology biological process

GO (Orthology)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
endopeptidase activity Hs molecular function
metalloendopeptidase activity Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
proteinaceous extracellular matrix Hs cellular component
extracellular space Hs cellular component
proteolysis Hs biological process
spermatogenesis Hs biological process
heparin binding Hs molecular function
peptidase activity Hs molecular function
metallopeptidase activity Hs molecular function
zinc ion binding Hs molecular function
protein processing Hs biological process
hydrolase activity Hs molecular function
collagen fibril organization Hs biological process
lung development Hs biological process
collagen catabolic process Hs biological process
extracellular matrix Hs cellular component
collagen biosynthetic process Hs biological process
skin development Hs biological process
metal ion binding Hs molecular function
extracellular exosome Hs cellular component
supramolecular fiber organization Hs biological process
positive regulation of vascular endothelial growth factor signaling pathway Hs biological process

GO (Blast)

14 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
endopeptidase activity Hs molecular function 924 0.0
metalloendopeptidase activity Hs molecular function 924 0.0
protein binding Hs molecular function 924 0.0
extracellular region Hs cellular component 924 0.0
proteinaceous extracellular matrix Hs cellular component 924 0.0
extracellular space Hs cellular component 924 0.0
heparin binding Hs molecular function 924 0.0
peptidase activity Hs molecular function 924 0.0
metallopeptidase activity Hs molecular function 924 0.0
zinc ion binding Hs molecular function 924 0.0
hydrolase activity Hs molecular function 924 0.0
extracellular matrix Hs cellular component 924 0.0
metal ion binding Hs molecular function 924 0.0
extracellular exosome Hs cellular component 924 0.0

GO (InterProScan)

4 results

GO Term Analysis Type e-value
metalloendopeptidase activity Pfam molecular function 3.1E-20
proteolysis Pfam biological process 3.1E-20
peptidase activity ProSiteProfiles molecular function 9.604
metallopeptidase activity Gene3D molecular function 2.0E-63