- Gene 'KH2012:KH.C10.135' >
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Gene Card
Best human hits
DNA2; IGHMBP2; UPF1
Species
Unique Gene ID
Harore.g00011531
Gene Model ID
Harore.CG.MTP2014.S90.g11531
Location
S90:99830..103488
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Znf_AN1 | Pfam | Zinc finger, AN1-type |
Helicase_ATP-bd | SMART | Helicase superfamily 1/2, ATP-binding domain |
AAA+_ATPase | SMART | AAA+ ATPase domain |
AN1-like_Znf | SUPERFAMILY | AN1-like Zinc finger |
SMUBP-2/Hcs1-like | TIGRFAM | Helicase SMUBP-2/Hcs1-like |
AN1-like_Znf | Gene3D | AN1-like Zinc finger |
Znf_AN1 | SMART | Zinc finger, AN1-type |
P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
R3H_dom | SMART | R3H domain |
Znf_AN1 | ProSiteProfiles | Zinc finger, AN1-type |
R3H_dom_sf | SUPERFAMILY | R3H domain superfamily |
R3H_dom | ProSiteProfiles | R3H domain |
R3H_dom_sf | Gene3D | R3H domain superfamily |
R3H_dom | Pfam | R3H domain |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
nucleic acid binding | Orthology | molecular function |
DNA binding | Orthology | molecular function |
chromatin binding | Blast | molecular function |
RNA binding | Orthology | molecular function |
catalytic activity | Blast | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Blast | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Blast | cellular component |
cytosol | Blast | cellular component |
DNA replication | Orthology | biological process |
DNA repair | Orthology | biological process |
transcription, DNA-templated | Orthology | biological process |
regulation of transcription, DNA-templated | Orthology | biological process |
transcription factor binding | Orthology | molecular function |
zinc ion binding | Orthology | molecular function |
membrane | Orthology | cellular component |
hydrolase activity | Orthology | molecular function |
axon | Orthology | cellular component |
cell projection | Orthology | cellular component |
metal ion binding | Orthology | molecular function |
protein homooligomerization | Orthology | biological process |
organelle organization | Orthology | biological process |
nucleoside-triphosphatase activity | Orthology | molecular function |
DNA metabolic process | Orthology | biological process |
cell projection part | Orthology | cellular component |
macromolecular complex binding | Orthology | molecular function |
intracellular non-membrane-bounded organelle | Blast | cellular component |
nuclear lumen | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
cytoplasmic part | Blast | cellular component |
macromolecular complex | Blast | cellular component |
mitochondrial matrix | Blast | cellular component |
nuclear part | Blast | cellular component |
sequence-specific DNA binding | Blast | molecular function |
cofactor binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
tRNA binding | Hs | molecular function |
nucleotide binding | Hs | molecular function |
nucleic acid binding | Hs | molecular function |
DNA binding | Hs | molecular function |
DNA helicase activity | Hs | molecular function |
single-stranded DNA binding | Hs | molecular function |
RNA binding | Hs | molecular function |
helicase activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
nucleus | Hs | cellular component |
cytoplasm | Hs | cellular component |
DNA replication | Hs | biological process |
DNA repair | Hs | biological process |
DNA recombination | Hs | biological process |
transcription, DNA-templated | Hs | biological process |
regulation of transcription, DNA-templated | Hs | biological process |
translation | Hs | biological process |
DNA-dependent ATPase activity | Hs | molecular function |
transcription factor binding | Hs | molecular function |
RNA-dependent ATPase activity | Hs | molecular function |
zinc ion binding | Hs | molecular function |
membrane | Hs | cellular component |
hydrolase activity | Hs | molecular function |
axon | Hs | cellular component |
growth cone | Hs | cellular component |
intracellular ribonucleoprotein complex | Hs | cellular component |
DNA duplex unwinding | Hs | biological process |
ATP-dependent 5'-3' RNA helicase activity | Hs | molecular function |
cell projection | Hs | cellular component |
ribosome binding | Hs | molecular function |
ATP-dependent 5'-3' DNA helicase activity | Hs | molecular function |
metal ion binding | Hs | molecular function |
protein homooligomerization | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
tRNA binding | Hs | molecular function | 681 | 0.0 |
nucleotide binding | Hs | molecular function | 681 | 0.0 |
nuclear chromosome, telomeric region | Hs | cellular component | 194 | 1.41e-50 |
chromatin | Hs | cellular component | 194 | 1.41e-50 |
P-body | Hs | cellular component | 194 | 1.41e-50 |
nucleic acid binding | Hs | molecular function | 681 | 0.0 |
DNA binding | Hs | molecular function | 681 | 0.0 |
DNA helicase activity | Hs | molecular function | 681 | 0.0 |
chromatin binding | Hs | molecular function | 194 | 1.41e-50 |
single-stranded DNA binding | Hs | molecular function | 681 | 0.0 |
RNA binding | Hs | molecular function | 681 | 0.0 |
catalytic activity | Hs | molecular function | 180 | 4.47e-46 |
ATP-dependent RNA helicase activity | Hs | molecular function | 194 | 1.41e-50 |
helicase activity | Hs | molecular function | 681 | 0.0 |
nuclease activity | Hs | molecular function | 180 | 4.47e-46 |
endonuclease activity | Hs | molecular function | 180 | 4.47e-46 |
protein binding | Hs | molecular function | 681 | 0.0 |
ATP binding | Hs | molecular function | 681 | 0.0 |
nucleus | Hs | cellular component | 681 | 0.0 |
nucleoplasm | Hs | cellular component | 194 | 1.41e-50 |
cytoplasm | Hs | cellular component | 681 | 0.0 |
mitochondrion | Hs | cellular component | 180 | 4.47e-46 |
gamma DNA polymerase complex | Hs | cellular component | 180 | 4.47e-46 |
cytosol | Hs | cellular component | 194 | 1.41e-50 |
DNA-dependent ATPase activity | Hs | molecular function | 681 | 0.0 |
transcription factor binding | Hs | molecular function | 681 | 0.0 |
RNA-dependent ATPase activity | Hs | molecular function | 681 | 0.0 |
zinc ion binding | Hs | molecular function | 681 | 0.0 |
membrane | Hs | cellular component | 681 | 0.0 |
hydrolase activity | Hs | molecular function | 681 | 0.0 |
ATPase activity | Hs | molecular function | 180 | 4.47e-46 |
site-specific endodeoxyribonuclease activity, specific for altered base | Hs | molecular function | 180 | 4.47e-46 |
5'-flap endonuclease activity | Hs | molecular function | 180 | 4.47e-46 |
axon | Hs | cellular component | 681 | 0.0 |
growth cone | Hs | cellular component | 681 | 0.0 |
intracellular ribonucleoprotein complex | Hs | cellular component | 681 | 0.0 |
ATP-dependent 5'-3' RNA helicase activity | Hs | molecular function | 681 | 0.0 |
exon-exon junction complex | Hs | cellular component | 194 | 1.41e-50 |
telomeric DNA binding | Hs | molecular function | 194 | 1.41e-50 |
mitochondrial nucleoid | Hs | cellular component | 180 | 4.47e-46 |
cell projection | Hs | cellular component | 681 | 0.0 |
ribosome binding | Hs | molecular function | 681 | 0.0 |
5'-3' DNA helicase activity | Hs | molecular function | 180 | 4.47e-46 |
ATP-dependent 5'-3' DNA helicase activity | Hs | molecular function | 681 | 0.0 |
single-stranded DNA-dependent ATPase activity | Hs | molecular function | 180 | 4.47e-46 |
supraspliceosomal complex | Hs | cellular component | 194 | 1.41e-50 |
metal ion binding | Hs | molecular function | 681 | 0.0 |
iron-sulfur cluster binding | Hs | molecular function | 180 | 4.47e-46 |
4 iron, 4 sulfur cluster binding | Hs | molecular function | 180 | 4.47e-46 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
nucleic acid binding | Gene3D | molecular function | 1.1E-13 |
DNA binding | TIGRFAM | molecular function | 1.5E-190 |
ATP binding | TIGRFAM | molecular function | 1.5E-190 |
zinc ion binding | Pfam | molecular function | 2.5E-9 |