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Gene Card

Best human hits

ACTN1; ACTN2; ACTN4

Species

H.roretzi

Unique Gene ID

Harore.g00007310

Gene Model ID

Harore.CG.MTP2014.S31.g07310

Location

S31:15685..27540

Transcript Models and Sequences

  Harore.CG.MTP2014.S31.g07310.01.t
Harore.CG.MTP2014.S31.g07310.02.t
Harore.CG.MTP2014.S31.g07310.03.t
Harore.CG.MTP2014.S31.g07310.04.t
Harore.CG.MTP2014.S31.g07310.05.t
Harore.CG.MTP2014.S31.g07310.06.t
Harore.CG.MTP2014.S31.g07310.07.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

14 results

IPR Term Analysis Definition
Spectrin/alpha-actinin SMART Spectrin/alpha-actinin
Alpha-actinin_1 PANTHER Alpha-actinin 1
Spectrin_repeat Pfam Spectrin repeat
EF_hand_dom SMART EF-hand domain
EF_Hand_1_Ca_BS ProSitePatterns EF-Hand 1, calcium-binding site
EF_hand_dom ProSiteProfiles EF-hand domain
EF-hand-dom_pair SUPERFAMILY EF-hand domain pair
CH_dom_sf Gene3D CH domain superfamily
Actinin_actin-bd_CS ProSitePatterns Actinin-type actin-binding domain, conserved site
CH-domain Pfam Calponin homology domain
CH-domain CDD Calponin homology domain
CH-domain ProSiteProfiles Calponin homology domain
CH_dom_sf SUPERFAMILY CH domain superfamily
CH-domain SMART Calponin homology domain

GOSlim

81 results

GO Term Annotation Origin Type
RNA polymerase II regulatory region sequence-specific DNA binding Orthology molecular function
nucleoside binding Orthology molecular function
RNA binding Orthology molecular function
actin binding Orthology molecular function
integrin binding Orthology molecular function
calcium ion binding Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
intracellular Orthology cellular component
nucleus Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
cytoskeleton Orthology cellular component
plasma membrane Orthology cellular component
brush border Orthology cellular component
focal adhesion Orthology cellular component
cell adhesion Orthology biological process
cytoskeletal protein binding Orthology molecular function
protein transport Orthology biological process
membrane Orthology cellular component
nuclear body Orthology cellular component
cell junction Orthology cellular component
macromolecular complex Orthology cellular component
identical protein binding Orthology molecular function
protein homodimerization activity Orthology molecular function
regulation of apoptotic process Orthology biological process
cell projection Orthology cellular component
metal ion binding Orthology molecular function
protein dimerization activity Orthology molecular function
perinuclear region of cytoplasm Orthology cellular component
actin filament binding Orthology molecular function
extracellular exosome Orthology cellular component
regulation of nucleic acid-templated transcription Orthology biological process
response to hypoxia Orthology biological process
neuron projection Orthology cellular component
protein N-terminus binding Orthology molecular function
intracellular signal transduction Orthology biological process
protein phosphorylation Orthology biological process
cytoskeletal part Orthology cellular component
plasma membrane region Orthology cellular component
cell leading edge Orthology cellular component
membrane organization Orthology biological process
organelle organization Orthology biological process
enzyme binding Orthology molecular function
molecular function regulator Orthology molecular function
anion binding Orthology molecular function
adherens junction Orthology cellular component
structural molecule activity Orthology molecular function
cytoplasmic part Orthology cellular component
organelle part Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
intracellular transport Orthology biological process
anatomical structure formation involved in morphogenesis Orthology biological process
immune system process Orthology biological process
animal organ development Orthology biological process
cell morphogenesis involved in differentiation Orthology biological process
cell migration Orthology biological process
transcription coactivator activity Orthology molecular function
cell periphery Orthology cellular component
intracellular organelle part Orthology cellular component
cytoplasmic vesicle Orthology cellular component
endomembrane system Orthology cellular component
intracellular organelle lumen Orthology cellular component
chromatin binding Orthology molecular function
DNA binding Orthology molecular function
receptor binding Orthology molecular function
transcription factor binding Orthology molecular function
signal transduction Orthology biological process
postsynapse Orthology cellular component
metal ion transport Orthology biological process
monovalent inorganic cation transport Orthology biological process
cell development Orthology biological process
protein homooligomerization Orthology biological process
heart development Orthology biological process
protein localization to membrane Orthology biological process
cellular protein localization Orthology biological process
transmembrane transport Orthology biological process
cation transport Orthology biological process
response to stimulus Orthology biological process
anatomical structure morphogenesis Orthology biological process

GO (Orthology)

94 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
MAPK cascade Hs biological process
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function
stress fiber Hs cellular component
ruffle Hs cellular component
nucleoside binding Hs molecular function
platelet degranulation Hs biological process
RNA binding Hs molecular function
double-stranded RNA binding Hs molecular function
actin binding Hs molecular function
Ras guanyl-nucleotide exchange factor activity Hs molecular function
integrin binding Hs molecular function
calcium ion binding Hs molecular function
protein binding Hs molecular function
phosphatidylinositol-4,5-bisphosphate binding Hs molecular function
extracellular region Hs cellular component
extracellular space Hs cellular component
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
actin filament Hs cellular component
plasma membrane Hs cellular component
brush border Hs cellular component
cell-cell junction Hs cellular component
fascia adherens Hs cellular component
focal adhesion Hs cellular component
muscle contraction Hs biological process
actin filament organization Hs biological process
cell adhesion Hs biological process
cytoskeletal protein binding Hs molecular function
structural constituent of muscle Hs molecular function
protein transport Hs biological process
actin cytoskeleton Hs cellular component
membrane Hs cellular component
nuclear body Hs cellular component
vinculin binding Hs molecular function
protein domain specific binding Hs molecular function
sarcomere Hs cellular component
Z disc Hs cellular component
vesicle transport along actin filament Hs biological process
cell junction Hs cellular component
filopodium Hs cellular component
platelet formation Hs biological process
LIM domain binding Hs molecular function
positive regulation of cell migration Hs biological process
ligand-dependent nuclear receptor transcription coactivator activity Hs molecular function
thyroid hormone receptor coactivator activity Hs molecular function
intracellular ribonucleoprotein complex Hs cellular component
cortical actin cytoskeleton Hs cellular component
platelet alpha granule lumen Hs cellular component
pseudopodium Hs cellular component
titin binding Hs molecular function
chromatin DNA binding Hs molecular function
macromolecular complex Hs cellular component
nuclear hormone receptor binding Hs molecular function
peroxisome proliferator activated receptor signaling pathway Hs biological process
regulation of membrane potential Hs biological process
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
retinoic acid receptor binding Hs molecular function
regulation of apoptotic process Hs biological process
cell projection Hs cellular component
dendritic spine Hs cellular component
negative regulation of potassium ion transport Hs biological process
ion channel binding Hs molecular function
sarcomere organization Hs biological process
metal ion binding Hs molecular function
protein dimerization activity Hs molecular function
focal adhesion assembly Hs biological process
retinoic acid receptor signaling pathway Hs biological process
perinuclear region of cytoplasm Hs cellular component
actin filament binding Hs molecular function
actin filament bundle assembly Hs biological process
protein homotetramerization Hs biological process
FATZ binding Hs molecular function
actin filament network formation Hs biological process
actin crosslink formation Hs biological process
cardiac muscle cell development Hs biological process
extracellular exosome Hs cellular component
titin Z domain binding Hs molecular function
protein localization to plasma membrane Hs biological process
negative regulation of substrate adhesion-dependent cell spreading Hs biological process
regulation of nucleic acid-templated transcription Hs biological process
negative regulation of protein localization to cell surface Hs biological process
positive regulation of cation channel activity Hs biological process
response to hypoxia Hs biological process
skeletal muscle atrophy Hs biological process
cortical cytoskeleton Hs cellular component
neuron projection Hs cellular component
protein N-terminus binding Hs molecular function
positive regulation of skeletal muscle fiber development Hs biological process
bone morphogenesis Hs biological process
bicellular tight junction assembly Hs biological process

GO (Blast)

60 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function 1056 0.0
stress fiber Hs cellular component 1102 0.0
ruffle Hs cellular component 1102 0.0
nucleoside binding Hs molecular function 1056 0.0
RNA binding Hs molecular function 1056 0.0
double-stranded RNA binding Hs molecular function 1102 0.0
actin binding Hs molecular function 1102 0.0
Ras guanyl-nucleotide exchange factor activity Hs molecular function 1093 0.0
integrin binding Hs molecular function 1102 0.0
calcium ion binding Hs molecular function 1102 0.0
protein binding Hs molecular function 1102 0.0
phosphatidylinositol-4,5-bisphosphate binding Hs molecular function 1093 0.0
extracellular region Hs cellular component 1102 0.0
extracellular space Hs cellular component 1102 0.0
intracellular Hs cellular component 1102 0.0
nucleus Hs cellular component 1056 0.0
cytoplasm Hs cellular component 1102 0.0
cytosol Hs cellular component 1102 0.0
cytoskeleton Hs cellular component 1102 0.0
actin filament Hs cellular component 1102 0.0
plasma membrane Hs cellular component 1102 0.0
brush border Hs cellular component 1102 0.0
cell-cell junction Hs cellular component 1102 0.0
fascia adherens Hs cellular component 1102 0.0
focal adhesion Hs cellular component 1102 0.0
cytoskeletal protein binding Hs molecular function 1093 0.0
structural constituent of muscle Hs molecular function 1093 0.0
actin cytoskeleton Hs cellular component 1056 0.0
membrane Hs cellular component 1102 0.0
nuclear body Hs cellular component 1056 0.0
vinculin binding Hs molecular function 1102 0.0
protein domain specific binding Hs molecular function 1093 0.0
sarcomere Hs cellular component 1102 0.0
Z disc Hs cellular component 1102 0.0
cell junction Hs cellular component 1102 0.0
filopodium Hs cellular component 1093 0.0
LIM domain binding Hs molecular function 1093 0.0
ligand-dependent nuclear receptor transcription coactivator activity Hs molecular function 1102 0.0
thyroid hormone receptor coactivator activity Hs molecular function 1093 0.0
intracellular ribonucleoprotein complex Hs cellular component 1056 0.0
cortical actin cytoskeleton Hs cellular component 1093 0.0
platelet alpha granule lumen Hs cellular component 1102 0.0
pseudopodium Hs cellular component 1102 0.0
titin binding Hs molecular function 1093 0.0
chromatin DNA binding Hs molecular function 1056 0.0
macromolecular complex Hs cellular component 1056 0.0
nuclear hormone receptor binding Hs molecular function 1056 0.0
identical protein binding Hs molecular function 1093 0.0
protein homodimerization activity Hs molecular function 1102 0.0
retinoic acid receptor binding Hs molecular function 1056 0.0
cell projection Hs cellular component 1102 0.0
dendritic spine Hs cellular component 1093 0.0
ion channel binding Hs molecular function 1102 0.0
metal ion binding Hs molecular function 1102 0.0
protein dimerization activity Hs molecular function 1093 0.0
perinuclear region of cytoplasm Hs cellular component 1056 0.0
actin filament binding Hs molecular function 1102 0.0
FATZ binding Hs molecular function 1093 0.0
extracellular exosome Hs cellular component 1102 0.0
titin Z domain binding Hs molecular function 1093 0.0

GO (InterProScan)

5 results

GO Term Analysis Type e-value
calcium ion binding SMART molecular function 1.6E-4
protein binding SMART molecular function 1.0E-22
actin filament binding PANTHER molecular function 1.9E-248
actin filament bundle assembly PANTHER biological process 1.9E-248
actin crosslink formation PANTHER biological process 1.9E-248

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