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GENE CARD

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Gene Card

Best human hits

SMG5; SMG6; SMG7

Species

H.roretzi

Unique Gene ID

Harore.g00002756

Gene Model ID

Harore.CG.MTP2014.S511.g02756

Location

S511:1197..8653

Transcript Models and Sequences

  Harore.CG.MTP2014.S511.g02756.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
EST1 Pfam Telomerase activating protein Est1
TPR-like_helical_dom_sf Gene3D Tetratricopeptide-like helical domain superfamily
PIN_dom Pfam PIN domain
DNA/RNA-bd_Est1-type Pfam DNA/RNA-binding domain, Est1-type
PIN_dom SMART PIN domain
TPR-like_helical_dom_sf SUPERFAMILY Tetratricopeptide-like helical domain superfamily
PIN-like_dom_sf SUPERFAMILY PIN-like domain superfamily

GOSlim

29 results

GO Term Annotation Origin Type
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Orthology biological process
DNA binding Orthology molecular function
RNA binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleolus Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
hydrolase activity Orthology molecular function
ubiquitin protein ligase binding Blast molecular function
metal ion binding Orthology molecular function
nuclear part Orthology cellular component
macromolecular complex Orthology cellular component
intracellular organelle part Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
RNA metabolic process Orthology biological process
intracellular protein transport Orthology biological process
gene expression Orthology biological process
organelle organization Orthology biological process
DNA metabolic process Orthology biological process
transferase activity, transferring phosphorus-containing groups Orthology molecular function
dephosphorylation Orthology biological process
regulation of cellular metabolic process Orthology biological process
sequence-specific DNA binding Orthology molecular function
macromolecular complex binding Orthology molecular function
RNA catabolic process Orthology biological process
regulation of gene expression Orthology biological process
enzyme binding Orthology molecular function
cytoskeleton Blast cellular component

GO (Orthology)

28 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Hs biological process
telomerase catalytic core complex Hs cellular component
chromosome, telomeric region Hs cellular component
DNA binding Hs molecular function
RNA binding Hs molecular function
nuclease activity Hs molecular function
endonuclease activity Hs molecular function
endoribonuclease activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
chromosome Hs cellular component
telomerase holoenzyme complex Hs cellular component
nucleolus Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
mRNA export from nucleus Hs biological process
hydrolase activity Hs molecular function
regulation of telomere maintenance via telomerase Hs biological process
exon-exon junction complex Hs cellular component
regulation of dephosphorylation Hs biological process
telomeric DNA binding Hs molecular function
ribonucleoprotein complex binding Hs molecular function
regulation of RNA stability Hs biological process
metal ion binding Hs molecular function
telomerase RNA binding Hs molecular function
DNA polymerase binding Hs molecular function
nucleic acid phosphodiester bond hydrolysis Hs biological process
RNA phosphodiester bond hydrolysis, endonucleolytic Hs biological process

GO (Blast)

26 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
telomerase catalytic core complex Hs cellular component 519 2.34e-161
chromosome, telomeric region Hs cellular component 519 2.34e-161
DNA binding Hs molecular function 519 2.34e-161
RNA binding Hs molecular function 519 2.34e-161
nuclease activity Hs molecular function 519 2.34e-161
endonuclease activity Hs molecular function 519 2.34e-161
endoribonuclease activity Hs molecular function 519 2.34e-161
ribonuclease activity Hs molecular function 104 1.64e-22
protein binding Hs molecular function 519 2.34e-161
nucleus Hs cellular component 519 2.34e-161
chromosome Hs cellular component 519 2.34e-161
telomerase holoenzyme complex Hs cellular component 519 2.34e-161
nucleolus Hs cellular component 519 2.34e-161
cytoplasm Hs cellular component 519 2.34e-161
cytosol Hs cellular component 519 2.34e-161
hydrolase activity Hs molecular function 519 2.34e-161
ubiquitin protein ligase binding Hs molecular function 84.0 3.43e-16
exon-exon junction complex Hs cellular component 519 2.34e-161
telomeric DNA binding Hs molecular function 519 2.34e-161
histone deacetylase binding Hs molecular function 84.0 3.43e-16
ribonucleoprotein complex binding Hs molecular function 519 2.34e-161
intermediate filament cytoskeleton Hs cellular component 104 1.64e-22
metal ion binding Hs molecular function 519 2.34e-161
protein phosphatase 2A binding Hs molecular function 104 1.64e-22
telomerase RNA binding Hs molecular function 519 2.34e-161
DNA polymerase binding Hs molecular function 519 2.34e-161

GO (InterProScan)

1 result

GO Term Analysis Type e-value
protein binding SUPERFAMILY molecular function 7.68E-74