Gene Card
Best human hits
HSP90AA1; HSP90AB1; HSP90B1
Species
Unique Gene ID
Harore.g00002269
Gene Model ID
Harore.CG.MTP2014.S113.g02269
Location
S113:112748..119603
Transcript Models and Sequences
Harore.CG.MTP2014.S113.g02269.01.t
Harore.CG.MTP2014.S113.g02269.02.t
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
HATPase_C | Pfam | Histidine kinase/HSP90-like ATPase |
HATPase_C_sf | Gene3D | Histidine kinase/HSP90-like ATPase superfamily |
Hsp90_fam | PIRSF | Heat shock protein Hsp90 family |
Hsp90_fam | PANTHER | Heat shock protein Hsp90 family |
HATPase_C_sf | SUPERFAMILY | Histidine kinase/HSP90-like ATPase superfamily |
Hsp90_fam | Pfam | Heat shock protein Hsp90 family |
Hsp90_N | PRINTS | Heat shock protein Hsp90, N-terminal |
HSP90_C | SUPERFAMILY | HSP90, C-terminal domain |
Heat_shock_protein_90_CS | ProSitePatterns | Heat shock protein Hsp90, conserved site |
HATPase_C | SMART | Histidine kinase/HSP90-like ATPase |
HATPase_C | CDD | Histidine kinase/HSP90-like ATPase |
Hsp90_fam | Hamap | Heat shock protein Hsp90 family |
HSP90_C | Gene3D | HSP90, C-terminal domain |
Ribosomal_S5_D2-typ_fold | SUPERFAMILY | Ribosomal protein S5 domain 2-type fold |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
response to hypoxia | Orthology | biological process |
RNA binding | Orthology | molecular function |
calcium ion binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
GTP binding | Blast | molecular function |
extracellular region | Orthology | cellular component |
intracellular | Blast | cellular component |
nucleus | Orthology | cellular component |
nucleoplasm | Blast | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Blast | cellular component |
lysosomal membrane | Blast | cellular component |
endoplasmic reticulum | Orthology | cellular component |
endoplasmic reticulum lumen | Orthology | cellular component |
endoplasmic reticulum membrane | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
focal adhesion | Orthology | cellular component |
protein folding | Orthology | biological process |
response to stress | Orthology | biological process |
signal transduction | Orthology | biological process |
cell surface | Blast | cellular component |
response to organic substance | Orthology | biological process |
protein transport | Orthology | biological process |
membrane | Orthology | cellular component |
basolateral plasma membrane | Blast | cellular component |
apical plasma membrane | Blast | cellular component |
cytokine-mediated signaling pathway | Orthology | biological process |
kinase binding | Blast | molecular function |
protein kinase binding | Blast | molecular function |
midbody | Orthology | cellular component |
brush border membrane | Blast | cellular component |
macromolecular complex | Orthology | cellular component |
melanosome | Orthology | cellular component |
identical protein binding | Blast | molecular function |
protein homodimerization activity | Blast | molecular function |
neuronal cell body | Blast | cellular component |
negative regulation of apoptotic process | Orthology | biological process |
myelin sheath | Blast | cellular component |
protein dimerization activity | Blast | molecular function |
perinuclear region of cytoplasm | Orthology | cellular component |
unfolded protein binding | Orthology | molecular function |
extracellular exosome | Orthology | cellular component |
innate immune response | Orthology | biological process |
membrane organization | Orthology | biological process |
organelle organization | Orthology | biological process |
enzyme binding | Orthology | molecular function |
cellular response to stress | Orthology | biological process |
proteolysis | Orthology | biological process |
intracellular protein transport | Orthology | biological process |
extracellular region part | Orthology | cellular component |
endoplasmic reticulum part | Orthology | cellular component |
cellular response to organic substance | Orthology | biological process |
protein dephosphorylation | Orthology | biological process |
regulation of cellular metabolic process | Orthology | biological process |
cellular protein modification process | Orthology | biological process |
receptor binding | Orthology | molecular function |
cellular process | Orthology | biological process |
cell | Orthology | cellular component |
localization | Orthology | biological process |
intracellular organelle part | Orthology | cellular component |
cytoplasmic vesicle | Orthology | cellular component |
intracellular organelle lumen | Orthology | cellular component |
anion binding | Blast | molecular function |
ribonucleotide binding | Blast | molecular function |
protein kinase activity | Blast | molecular function |
binding | Blast | molecular function |
nuclear part | Blast | cellular component |
intracellular part | Blast | cellular component |
nucleoside-triphosphatase activity | Blast | molecular function |
enzyme regulator activity | Blast | molecular function |
macromolecular complex binding | Blast | molecular function |
oxidation-reduction process | Blast | biological process |
adenyl nucleotide binding | Blast | molecular function |
carbohydrate derivative binding | Blast | molecular function |
cell projection membrane | Blast | cellular component |
cell leading edge | Blast | cellular component |
endomembrane system | Blast | cellular component |
lysosome | Blast | cellular component |
vacuolar part | Blast | cellular component |
axon | Blast | cellular component |
cell projection part | Blast | cellular component |
cell adhesion molecule binding | Blast | molecular function |
cytoskeletal protein binding | Blast | molecular function |
plasma membrane region | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
response to hypoxia | Hs | biological process |
toll-like receptor signaling pathway | Hs | biological process |
RNA binding | Hs | molecular function |
calcium ion binding | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
extracellular region | Hs | cellular component |
nucleus | Hs | cellular component |
endoplasmic reticulum | Hs | cellular component |
endoplasmic reticulum lumen | Hs | cellular component |
endoplasmic reticulum membrane | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
focal adhesion | Hs | cellular component |
protein folding | Hs | biological process |
receptor-mediated endocytosis | Hs | biological process |
response to stress | Hs | biological process |
protein transport | Hs | biological process |
membrane | Hs | cellular component |
cytokine-mediated signaling pathway | Hs | biological process |
protein phosphatase binding | Hs | molecular function |
ubiquitin-dependent ERAD pathway | Hs | biological process |
midbody | Hs | cellular component |
retrograde protein transport, ER to cytosol | Hs | biological process |
extracellular matrix | Hs | cellular component |
macromolecular complex | Hs | cellular component |
endoplasmic reticulum chaperone complex | Hs | cellular component |
protein folding in endoplasmic reticulum | Hs | biological process |
response to endoplasmic reticulum stress | Hs | biological process |
ATF6-mediated unfolded protein response | Hs | biological process |
melanosome | Hs | cellular component |
negative regulation of apoptotic process | Hs | biological process |
regulation of phosphoprotein phosphatase activity | Hs | biological process |
post-translational protein modification | Hs | biological process |
perinuclear region of cytoplasm | Hs | cellular component |
low-density lipoprotein particle receptor binding | Hs | molecular function |
unfolded protein binding | Hs | molecular function |
sequestering of calcium ion | Hs | biological process |
extracellular exosome | Hs | cellular component |
endocytic vesicle lumen | Hs | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 1025 | 0.0 |
UTP binding | Hs | molecular function | 575 | 0.0 |
CTP binding | Hs | molecular function | 575 | 0.0 |
RNA binding | Hs | molecular function | 1025 | 0.0 |
double-stranded RNA binding | Hs | molecular function | 575 | 0.0 |
protein tyrosine kinase activity | Hs | molecular function | 566 | 0.0 |
calcium ion binding | Hs | molecular function | 1025 | 0.0 |
protein binding | Hs | molecular function | 1025 | 0.0 |
ATP binding | Hs | molecular function | 1025 | 0.0 |
GTP binding | Hs | molecular function | 575 | 0.0 |
extracellular region | Hs | cellular component | 1025 | 0.0 |
intracellular | Hs | cellular component | 575 | 0.0 |
nucleus | Hs | cellular component | 1025 | 0.0 |
nucleoplasm | Hs | cellular component | 575 | 0.0 |
cytoplasm | Hs | cellular component | 575 | 0.0 |
mitochondrion | Hs | cellular component | 575 | 0.0 |
lysosomal membrane | Hs | cellular component | 575 | 0.0 |
endoplasmic reticulum | Hs | cellular component | 1025 | 0.0 |
endoplasmic reticulum lumen | Hs | cellular component | 1025 | 0.0 |
endoplasmic reticulum membrane | Hs | cellular component | 1025 | 0.0 |
cytosol | Hs | cellular component | 1025 | 0.0 |
plasma membrane | Hs | cellular component | 1025 | 0.0 |
focal adhesion | Hs | cellular component | 1025 | 0.0 |
drug binding | Hs | molecular function | 575 | 0.0 |
COP9 signalosome | Hs | cellular component | 575 | 0.0 |
cell surface | Hs | cellular component | 575 | 0.0 |
membrane | Hs | cellular component | 1025 | 0.0 |
inclusion body | Hs | cellular component | 575 | 0.0 |
basolateral plasma membrane | Hs | cellular component | 575 | 0.0 |
apical plasma membrane | Hs | cellular component | 575 | 0.0 |
ATPase activity | Hs | molecular function | 566 | 0.0 |
sulfonylurea receptor binding | Hs | molecular function | 575 | 0.0 |
protein kinase regulator activity | Hs | molecular function | 575 | 0.0 |
kinase binding | Hs | molecular function | 575 | 0.0 |
protein kinase binding | Hs | molecular function | 575 | 0.0 |
protein phosphatase binding | Hs | molecular function | 1025 | 0.0 |
MHC class II protein complex binding | Hs | molecular function | 575 | 0.0 |
nitric-oxide synthase regulator activity | Hs | molecular function | 575 | 0.0 |
midbody | Hs | cellular component | 1025 | 0.0 |
TPR domain binding | Hs | molecular function | 575 | 0.0 |
extracellular matrix | Hs | cellular component | 1025 | 0.0 |
heat shock protein binding | Hs | molecular function | 575 | 0.0 |
brush border membrane | Hs | cellular component | 575 | 0.0 |
dATP binding | Hs | molecular function | 575 | 0.0 |
ruffle membrane | Hs | cellular component | 566 | 0.0 |
macromolecular complex | Hs | cellular component | 1025 | 0.0 |
endoplasmic reticulum chaperone complex | Hs | cellular component | 1025 | 0.0 |
aryl hydrocarbon receptor complex | Hs | cellular component | 575 | 0.0 |
secretory granule lumen | Hs | cellular component | 575 | 0.0 |
peptide binding | Hs | molecular function | 575 | 0.0 |
melanosome | Hs | cellular component | 1025 | 0.0 |
identical protein binding | Hs | molecular function | 575 | 0.0 |
protein homodimerization activity | Hs | molecular function | 575 | 0.0 |
histone deacetylase binding | Hs | molecular function | 575 | 0.0 |
ATP-dependent protein binding | Hs | molecular function | 575 | 0.0 |
neuronal cell body | Hs | cellular component | 575 | 0.0 |
lysosomal lumen | Hs | cellular component | 566 | 0.0 |
myelin sheath | Hs | cellular component | 566 | 0.0 |
dendritic growth cone | Hs | cellular component | 575 | 0.0 |
axonal growth cone | Hs | cellular component | 575 | 0.0 |
ion channel binding | Hs | molecular function | 575 | 0.0 |
cadherin binding | Hs | molecular function | 575 | 0.0 |
protein dimerization activity | Hs | molecular function | 575 | 0.0 |
tau protein binding | Hs | molecular function | 575 | 0.0 |
perinuclear region of cytoplasm | Hs | cellular component | 1025 | 0.0 |
low-density lipoprotein particle receptor binding | Hs | molecular function | 1025 | 0.0 |
GTPase binding | Hs | molecular function | 566 | 0.0 |
unfolded protein binding | Hs | molecular function | 1025 | 0.0 |
extracellular exosome | Hs | cellular component | 1025 | 0.0 |
DNA polymerase binding | Hs | molecular function | 575 | 0.0 |
endocytic vesicle lumen | Hs | cellular component | 1025 | 0.0 |
scaffold protein binding | Hs | molecular function | 566 | 0.0 |
disordered domain specific binding | Hs | molecular function | 575 | 0.0 |
ficolin-1-rich granule lumen | Hs | cellular component | 575 | 0.0 |
histone methyltransferase binding | Hs | molecular function | 575 | 0.0 |
protein tyrosine kinase binding | Hs | molecular function | 566 | 0.0 |
sperm head plasma membrane | Hs | cellular component | 575 | 0.0 |
ooplasm | Hs | cellular component | 575 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ATP binding | PANTHER | molecular function | 0.0 |
protein folding | PANTHER | biological process | 0.0 |
response to stress | PANTHER | biological process | 0.0 |
unfolded protein binding | PANTHER | molecular function | 0.0 |