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Genomicus Synteny Browser

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Gene Phylogeny

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Gene Annotations

InterPro

34 results

IPR Term	Analysis	Definition
DH-domain	SMART	Dbl homology (DH) domain
DBL_dom_sf	Gene3D	Dbl homology (DH) domain superfamily
DH-domain	Pfam	Dbl homology (DH) domain
SH2	SMART	SH2 domain
CH_dom_sf	Gene3D	CH domain superfamily
CH-domain	ProSiteProfiles	Calponin homology domain
Vav1	PANTHER	Protein vav1
GDS_CDC24_CS	ProSitePatterns	Guanine-nucleotide dissociation stimulator, CDC24, conserved site
CH-domain	Pfam	Calponin homology domain
SH2	ProSiteProfiles	SH2 domain
CH-domain	CDD	Calponin homology domain
DH-domain	ProSiteProfiles	Dbl homology (DH) domain
SH2_dom_sf	SUPERFAMILY	SH2 domain superfamily
SM22_calponin	PRINTS	Smooth muscle protein/calponin
SH3_domain	Pfam	SH3 domain
PE/DAG-bd	ProSiteProfiles	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
SH3_domain	ProSiteProfiles	SH3 domain
SH2	PRINTS	SH2 domain
PH_domain	Pfam	Pleckstrin homology domain
SH2_dom_sf	Gene3D	SH2 domain superfamily
DH-domain	CDD	Dbl homology (DH) domain
SH3-like_dom_sf	SUPERFAMILY	SH3-like domain superfamily
SH3_domain	SMART	SH3 domain
PH_domain	ProSiteProfiles	Pleckstrin homology domain
CH-domain	SMART	Calponin homology domain
PH_domain	SMART	Pleckstrin homology domain
PH-like_dom_sf	Gene3D	PH-like domain superfamily
PE/DAG-bd	Pfam	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
DBL_dom_sf	SUPERFAMILY	Dbl homology (DH) domain superfamily
PE/DAG-bd	CDD	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
CH_dom_sf	SUPERFAMILY	CH domain superfamily
SH3_domain	PRINTS	SH3 domain
PE/DAG-bd	SMART	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
SH2	Pfam	SH2 domain

GOSlim

47 results

GO Term	Annotation Origin	Type
angiogenesis	Orthology	biological process
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
GTPase activator activity	Orthology	molecular function
protein binding	Orthology	molecular function
intracellular	Orthology	cellular component
cytoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
plasma membrane	Orthology	cellular component
regulation of transcription, DNA-templated	Orthology	biological process
immune response	Orthology	biological process
cellular response to DNA damage stimulus	Orthology	biological process
signal transduction	Orthology	biological process
G-protein coupled receptor signaling pathway	Orthology	biological process
small GTPase mediated signal transduction	Orthology	biological process
positive regulation of signal transduction	Orthology	biological process
cell migration	Orthology	biological process
cytokine-mediated signaling pathway	Orthology	biological process
cell projection assembly	Orthology	biological process
intracellular signal transduction	Orthology	biological process
positive regulation of apoptotic process	Orthology	biological process
regulation of GTPase activity	Orthology	biological process
positive regulation of GTPase activity	Orthology	biological process
metal ion binding	Orthology	molecular function
regulation of molecular function	Orthology	biological process
extracellular exosome	Orthology	cellular component
enzyme binding	Orthology	molecular function
molecular function regulator	Orthology	molecular function
receptor binding	Orthology	molecular function
cell junction	Orthology	cellular component
membrane organization	Orthology	biological process
organelle organization	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
cellular component organization	Orthology	biological process
blood coagulation	Orthology	biological process
cellular process	Orthology	biological process
immune system process	Orthology	biological process
animal organ development	Orthology	biological process
cell differentiation	Orthology	biological process
chemotaxis	Orthology	biological process
regulation of signal transduction	Orthology	biological process
cell adhesion	Orthology	biological process
innate immune response	Orthology	biological process
phosphorylation	Orthology	biological process
organic substance metabolic process	Orthology	biological process
phosphotransferase activity, alcohol group as acceptor	Orthology	molecular function
kinase activity	Orthology	molecular function
cellular metabolic process	Orthology	biological process

GO (Orthology)

54 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
angiogenesis	Hs	biological process
phosphotyrosine residue binding	Hs	molecular function
transcription factor activity, sequence-specific DNA binding	Hs	molecular function
SH3/SH2 adaptor activity	Hs	molecular function
guanyl-nucleotide exchange factor activity	Hs	molecular function
Rho guanyl-nucleotide exchange factor activity	Hs	molecular function
GTPase activator activity	Hs	molecular function
epidermal growth factor receptor binding	Hs	molecular function
protein binding	Hs	molecular function
intracellular	Hs	cellular component
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
plasma membrane	Hs	cellular component
cell-cell junction	Hs	cellular component
regulation of transcription, DNA-templated	Hs	biological process
vesicle fusion	Hs	biological process
phagocytosis	Hs	biological process
immune response	Hs	biological process
cellular response to DNA damage stimulus	Hs	biological process
signal transduction	Hs	biological process
G-protein coupled receptor signaling pathway	Hs	biological process
integrin-mediated signaling pathway	Hs	biological process
small GTPase mediated signal transduction	Hs	biological process
regulation of cell size	Hs	biological process
positive regulation of signal transduction	Hs	biological process
cell migration	Hs	biological process
cytokine-mediated signaling pathway	Hs	biological process
cell projection assembly	Hs	biological process
lamellipodium assembly	Hs	biological process
platelet activation	Hs	biological process
T cell differentiation	Hs	biological process
neutrophil chemotaxis	Hs	biological process
Rac guanyl-nucleotide exchange factor activity	Hs	molecular function
regulation of Rho protein signal transduction	Hs	biological process
intracellular signal transduction	Hs	biological process
Fc-epsilon receptor signaling pathway	Hs	biological process
T cell activation	Hs	biological process
response to drug	Hs	biological process
positive regulation of apoptotic process	Hs	biological process
regulation of GTPase activity	Hs	biological process
positive regulation of GTPase activity	Hs	biological process
positive regulation of cell adhesion	Hs	biological process
positive regulation of natural killer cell mediated cytotoxicity	Hs	biological process
phosphatidylinositol phosphorylation	Hs	biological process
metal ion binding	Hs	molecular function
phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Hs	molecular function
vascular endothelial growth factor receptor signaling pathway	Hs	biological process
ephrin receptor signaling pathway	Hs	biological process
B cell receptor signaling pathway	Hs	biological process
regulation of small GTPase mediated signal transduction	Hs	biological process
positive regulation of protein kinase B signaling	Hs	biological process
regulation of molecular function	Hs	biological process
extracellular exosome	Hs	cellular component
reactive oxygen species metabolic process	Hs	biological process

GO (Blast)

17 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
phosphotyrosine residue binding	Hs	molecular function	508	1.06e-166
transcription factor activity, sequence-specific DNA binding	Hs	molecular function	508	1.06e-166
SH3/SH2 adaptor activity	Hs	molecular function	511	3.55e-167
guanyl-nucleotide exchange factor activity	Hs	molecular function	511	3.55e-167
Rho guanyl-nucleotide exchange factor activity	Hs	molecular function	511	3.55e-167
GTPase activator activity	Hs	molecular function	511	3.55e-167
epidermal growth factor receptor binding	Hs	molecular function	511	3.55e-167
protein binding	Hs	molecular function	511	3.55e-167
intracellular	Hs	cellular component	511	3.55e-167
cytoplasm	Hs	cellular component	511	3.55e-167
cytosol	Hs	cellular component	511	3.55e-167
plasma membrane	Hs	cellular component	511	3.55e-167
cell-cell junction	Hs	cellular component	508	1.06e-166
Rac guanyl-nucleotide exchange factor activity	Hs	molecular function	511	3.55e-167
metal ion binding	Hs	molecular function	511	3.55e-167
phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Hs	molecular function	508	1.06e-166
extracellular exosome	Hs	cellular component	511	3.55e-167

GO (InterProScan)

6 results

GO Term	Analysis	Type	e-value
guanyl-nucleotide exchange factor activity	ProSitePatterns	molecular function
Rho guanyl-nucleotide exchange factor activity	SMART	molecular function	6.1E-46
protein binding	SMART	molecular function	4.8E-20
small GTPase mediated signal transduction	PANTHER	biological process	4.8E-185
regulation of Rho protein signal transduction	SMART	biological process	6.1E-46
intracellular signal transduction	CDD	biological process	3.98775E-11

Gene Card

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