Gene Card
Best human hits
ERN2; PINK1; STK35
Species
Unique Gene ID
Harore.g00000684
Gene Model ID
Harore.CG.MTP2014.S27.g00684
Location
S27:129369..134072
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
Prot_kinase_dom | Pfam | Protein kinase domain |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Prot_kinase_dom | SMART | Protein kinase domain |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
magnesium ion binding | Orthology | molecular function |
catalytic activity | Blast | molecular function |
protein kinase activity | Orthology | molecular function |
protein serine/threonine kinase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleolus | Blast | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Orthology | cellular component |
mitochondrial inner membrane | Orthology | cellular component |
endoplasmic reticulum | Blast | cellular component |
endoplasmic reticulum membrane | Blast | cellular component |
cytosol | Orthology | cellular component |
cytoskeleton | Orthology | cellular component |
protein phosphorylation | Orthology | biological process |
response to oxidative stress | Orthology | biological process |
negative regulation of gene expression | Orthology | biological process |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
protein ubiquitination | Orthology | biological process |
nuclear body | Blast | cellular component |
transferase activity | Orthology | molecular function |
hydrolase activity | Blast | molecular function |
axon | Orthology | cellular component |
ubiquitin protein ligase binding | Orthology | molecular function |
intracellular signal transduction | Orthology | biological process |
negative regulation of apoptotic process | Orthology | biological process |
cell body | Orthology | cellular component |
metal ion binding | Orthology | molecular function |
perinuclear region of cytoplasm | Orthology | cellular component |
intracellular part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
organelle organization | Orthology | biological process |
intracellular organelle part | Orthology | cellular component |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
enzyme binding | Orthology | molecular function |
transmembrane transport | Orthology | biological process |
monovalent inorganic cation transport | Orthology | biological process |
regulation of cellular metabolic process | Orthology | biological process |
response to stress | Orthology | biological process |
whole membrane | Orthology | cellular component |
mitochondrial membrane | Orthology | cellular component |
bounding membrane of organelle | Orthology | cellular component |
membrane part | Orthology | cellular component |
mitochondrial envelope | Orthology | cellular component |
intracellular organelle lumen | Orthology | cellular component |
proteolysis | Orthology | biological process |
peptidase activity | Orthology | molecular function |
positive regulation of hydrolase activity | Orthology | biological process |
enzyme activator activity | Orthology | molecular function |
oxidation-reduction process | Orthology | biological process |
cellular metabolic process | Orthology | biological process |
cell projection part | Orthology | cellular component |
chemical synaptic transmission | Orthology | biological process |
cellular response to stress | Orthology | biological process |
protein dephosphorylation | Orthology | biological process |
transcription factor activity, sequence-specific DNA binding | Orthology | molecular function |
positive regulation of signal transduction | Orthology | biological process |
protein kinase binding | Orthology | molecular function |
regulation of apoptotic process | Orthology | biological process |
positive regulation of gene expression | Orthology | biological process |
negative regulation of signal transduction | Orthology | biological process |
positive regulation of catalytic activity | Orthology | biological process |
ubiquitin-protein transferase activity | Orthology | molecular function |
response to hypoxia | Orthology | biological process |
anatomical structure morphogenesis | Orthology | biological process |
positive regulation of apoptotic process | Orthology | biological process |
neuron part | Orthology | cellular component |
cell projection | Orthology | cellular component |
plasma membrane region | Orthology | cellular component |
negative regulation of cell death | Orthology | biological process |
ubiquitin-like protein transferase activity | Orthology | molecular function |
ligase activity | Orthology | molecular function |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
phosphate-containing compound metabolic process | Orthology | biological process |
RNA metabolic process | Blast | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
ubiquitin ligase complex | Hs | cellular component | 199 | 4.06e-56 |
nucleotide binding | Hs | molecular function | 199 | 4.06e-56 |
magnesium ion binding | Hs | molecular function | 199 | 4.06e-56 |
chromatin | Hs | cellular component | 199 | 4.06e-56 |
protease binding | Hs | molecular function | 199 | 4.06e-56 |
catalytic activity | Hs | molecular function | 59.3 | 5.01e-09 |
endonuclease activity | Hs | molecular function | 59.3 | 5.01e-09 |
ribonuclease activity | Hs | molecular function | 59.3 | 5.01e-09 |
protein kinase activity | Hs | molecular function | 199 | 4.06e-56 |
protein serine/threonine kinase activity | Hs | molecular function | 199 | 4.06e-56 |
protein binding | Hs | molecular function | 199 | 4.06e-56 |
ATP binding | Hs | molecular function | 199 | 4.06e-56 |
nucleus | Hs | cellular component | 199 | 4.06e-56 |
nucleolus | Hs | cellular component | 51.2 | 1.32e-06 |
cytoplasm | Hs | cellular component | 199 | 4.06e-56 |
mitochondrion | Hs | cellular component | 199 | 4.06e-56 |
mitochondrial outer membrane | Hs | cellular component | 199 | 4.06e-56 |
mitochondrial outer membrane translocase complex | Hs | cellular component | 199 | 4.06e-56 |
mitochondrial inner membrane | Hs | cellular component | 199 | 4.06e-56 |
mitochondrial intermembrane space | Hs | cellular component | 199 | 4.06e-56 |
endoplasmic reticulum | Hs | cellular component | 59.3 | 5.01e-09 |
endoplasmic reticulum membrane | Hs | cellular component | 59.3 | 5.01e-09 |
cytosol | Hs | cellular component | 199 | 4.06e-56 |
cytoskeleton | Hs | cellular component | 199 | 4.06e-56 |
calcium-dependent protein kinase activity | Hs | molecular function | 199 | 4.06e-56 |
membrane | Hs | cellular component | 199 | 4.06e-56 |
integral component of membrane | Hs | cellular component | 199 | 4.06e-56 |
kinase activity | Hs | molecular function | 199 | 4.06e-56 |
peptidase activator activity | Hs | molecular function | 199 | 4.06e-56 |
nuclear body | Hs | cellular component | 51.2 | 1.32e-06 |
transferase activity | Hs | molecular function | 199 | 4.06e-56 |
hydrolase activity | Hs | molecular function | 59.3 | 5.01e-09 |
axon | Hs | cellular component | 199 | 4.06e-56 |
growth cone | Hs | cellular component | 199 | 4.06e-56 |
integral component of mitochondrial outer membrane | Hs | cellular component | 199 | 4.06e-56 |
ubiquitin protein ligase binding | Hs | molecular function | 199 | 4.06e-56 |
TORC2 complex | Hs | cellular component | 199 | 4.06e-56 |
protein kinase B binding | Hs | molecular function | 199 | 4.06e-56 |
cell body | Hs | cellular component | 199 | 4.06e-56 |
metal ion binding | Hs | molecular function | 199 | 4.06e-56 |
perinuclear region of cytoplasm | Hs | cellular component | 199 | 4.06e-56 |
C3HC4-type RING finger domain binding | Hs | molecular function | 199 | 4.06e-56 |
Lewy body | Hs | cellular component | 199 | 4.06e-56 |
astrocyte projection | Hs | cellular component | 199 | 4.06e-56 |
IRE1-TRAF2-ASK1 complex | Hs | cellular component | 59.3 | 5.01e-09 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 6.1E-17 |
ATP binding | Pfam | molecular function | 6.1E-17 |
protein phosphorylation | Pfam | biological process | 6.1E-17 |