Gene Card
Best human hits
AC011462.1; PDHA1; PDHA2
Species
Unique Gene ID
Cisavi.g00009111
Gene Model ID
Cisavi.CG.ENS81.R54.56166-61610
Location
R54:56165..61610
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
3 results
| IPR Term | Analysis | Definition |
|---|---|---|
| THDP-binding | SUPERFAMILY | Thiamin diphosphate-binding fold |
| Pyrv_DH_E1_asu_subgrp-y | TIGRFAM | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y |
| DH_E1 | Pfam | Dehydrogenase, E1 component |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
20 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| pyruvate dehydrogenase activity | Hs | molecular function |
| pyruvate dehydrogenase (acetyl-transferring) activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| nucleus | Hs | cellular component |
| nucleolus | Hs | cellular component |
| mitochondrion | Hs | cellular component |
| mitochondrial matrix | Hs | cellular component |
| carbohydrate metabolic process | Hs | biological process |
| glucose metabolic process | Hs | biological process |
| acetyl-CoA biosynthetic process from pyruvate | Hs | biological process |
| pyruvate metabolic process | Hs | biological process |
| tricarboxylic acid cycle | Hs | biological process |
| metabolic process | Hs | biological process |
| oxidoreductase activity | Hs | molecular function |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Hs | molecular function |
| pyruvate dehydrogenase (NAD+) activity | Hs | molecular function |
| myelin sheath | Hs | cellular component |
| intracellular membrane-bounded organelle | Hs | cellular component |
| pyruvate dehydrogenase complex | Hs | cellular component |
| oxidation-reduction process | Hs | biological process |
GO (Blast)
15 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| alpha-ketoacid dehydrogenase activity | Hs | molecular function | 117 | 1.05e-29 |
| 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity | Hs | molecular function | 117 | 1.05e-29 |
| pyruvate dehydrogenase activity | Hs | molecular function | 405 | 5.28e-141 |
| pyruvate dehydrogenase (acetyl-transferring) activity | Hs | molecular function | 405 | 1.14e-141 |
| protein binding | Hs | molecular function | 405 | 5.28e-141 |
| nucleus | Hs | cellular component | 405 | 1.14e-141 |
| nucleolus | Hs | cellular component | 405 | 1.14e-141 |
| mitochondrion | Hs | cellular component | 405 | 1.14e-141 |
| mitochondrial matrix | Hs | cellular component | 405 | 1.14e-141 |
| oxidoreductase activity | Hs | molecular function | 405 | 1.14e-141 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Hs | molecular function | 405 | 1.14e-141 |
| pyruvate dehydrogenase (NAD+) activity | Hs | molecular function | 405 | 1.14e-141 |
| myelin sheath | Hs | cellular component | 405 | 5.28e-141 |
| intracellular membrane-bounded organelle | Hs | cellular component | 405 | 1.14e-141 |
| pyruvate dehydrogenase complex | Hs | cellular component | 405 | 1.14e-141 |
GO (InterProScan)
5 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| pyruvate dehydrogenase (acetyl-transferring) activity | TIGRFAM | molecular function | 8.6E-124 |
| acetyl-CoA biosynthetic process from pyruvate | TIGRFAM | biological process | 8.6E-124 |
| metabolic process | Pfam | biological process | 6.6E-113 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Pfam | molecular function | 6.6E-113 |
| intracellular membrane-bounded organelle | TIGRFAM | cellular component | 8.6E-124 |
