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GENE CARD

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Gene Card

Best human hits

BTRC; FBXW11; FBXW7

Species

C.savignyi

Unique Gene ID

Cisavi.g00007985

Gene Model ID

Cisavi.CG.ENS81.R48.1524200-1537567

Location

R48:1524199..1537567

Transcript Models and Sequences

  Cisavi.CG.ENS81.R48.1524200-1537567.17856.t
Cisavi.CG.ENS81.R48.1524200-1537567.17857.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

14 results

IPR Term Analysis Definition
Beta-TrCP_D Pfam D domain of beta-TrCP
Beta-TrCP_D SMART D domain of beta-TrCP
G-protein_beta_WD-40_rep PRINTS G-protein beta WD-40 repeat
WD40_repeat_dom ProSiteProfiles WD40-repeat-containing domain
F-box_dom ProSiteProfiles F-box domain
WD40_repeat ProSiteProfiles WD40 repeat
WD40_repeat Pfam WD40 repeat
F-box_dom SMART F-box domain
WD40_repeat SMART WD40 repeat
WD40/YVTN_repeat-like_dom_sf Gene3D WD40/YVTN repeat-like-containing domain superfamily
F-box_dom Pfam F-box domain
WD40_repeat_CS ProSitePatterns WD40 repeat, conserved site
WD40_repeat_dom_sf SUPERFAMILY WD40-repeat-containing domain superfamily
F-box-like_dom_sf SUPERFAMILY F-box-like domain superfamily

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

46 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
G2/M transition of mitotic cell cycle Hs biological process
ubiquitin ligase complex Hs cellular component
protein polyubiquitination Hs biological process
ubiquitin-protein transferase activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
centrosome Hs cellular component
cytosol Hs cellular component
protein dephosphorylation Hs biological process
ubiquitin-dependent protein catabolic process Hs biological process
cell cycle Hs biological process
signal transduction Hs biological process
beta-catenin binding Hs molecular function
viral process Hs biological process
Wnt signaling pathway Hs biological process
protein ubiquitination Hs biological process
ligase activity Hs molecular function
SCF ubiquitin ligase complex Hs cellular component
protein catabolic process Hs biological process
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Hs biological process
protein destabilization Hs biological process
NIK/NF-kappaB signaling Hs biological process
Fc-epsilon receptor signaling pathway Hs biological process
regulation of circadian rhythm Hs biological process
positive regulation of circadian rhythm Hs biological process
regulation of I-kappaB kinase/NF-kappaB signaling Hs biological process
proteasome-mediated ubiquitin-dependent protein catabolic process Hs biological process
negative regulation of sequence-specific DNA binding transcription factor activity Hs biological process
post-translational protein modification Hs biological process
protein phosphorylated amino acid binding Hs molecular function
positive regulation of proteolysis Hs biological process
negative regulation of smoothened signaling pathway Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
protein dimerization activity Hs molecular function
rhythmic process Hs biological process
T cell receptor signaling pathway Hs biological process
stress-activated MAPK cascade Hs biological process
regulation of cell cycle Hs biological process
regulation of canonical Wnt signaling pathway Hs biological process
regulation of proteasomal protein catabolic process Hs biological process
ubiquitin protein ligase activity Hs molecular function
interleukin-1-mediated signaling pathway Hs biological process
cellular response to organic cyclic compound Hs biological process

GO (Blast)

22 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
ubiquitin ligase complex Hs cellular component 802 0.0
ubiquitin-protein transferase activity Hs molecular function 810 0.0
protein binding Hs molecular function 810 0.0
nucleus Hs cellular component 810 0.0
nucleoplasm Hs cellular component 810 0.0
nucleolus Hs cellular component 230 1.30e-66
cytoplasm Hs cellular component 810 0.0
centrosome Hs cellular component 802 0.0
cytosol Hs cellular component 810 0.0
beta-catenin binding Hs molecular function 810 0.0
ligase activity Hs molecular function 810 0.0
SCF ubiquitin ligase complex Hs cellular component 810 0.0
cyclin binding Hs molecular function 230 1.30e-66
protein binding, bridging Hs molecular function 230 1.30e-66
ubiquitin protein ligase binding Hs molecular function 230 1.30e-66
identical protein binding Hs molecular function 230 1.30e-66
protein phosphorylated amino acid binding Hs molecular function 810 0.0
protein dimerization activity Hs molecular function 810 0.0
phosphothreonine residue binding Hs molecular function 230 1.30e-66
ubiquitin protein ligase activity Hs molecular function 810 0.0
ubiquitin-protein transferase activator activity Hs molecular function 230 1.30e-66
Parkin-FBXW7-Cul1 ubiquitin ligase complex Hs cellular component 230 1.30e-66

GO (InterProScan)

2 results

GO Term Analysis Type e-value
protein binding Gene3D molecular function 2.6E-105
protein dimerization activity SMART molecular function 3.3E-26

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