Gene Card
Best human hits
TRAF2; TRAF3; TRAF4
Species
Unique Gene ID
Cisavi.g00005969
Gene Model ID
Cisavi.CG.ENS81.R3.1347971-1357962
Location
R3:1347970..1357962
Transcript Models and Sequences
Cisavi.CG.ENS81.R3.1347971-1357962.09076.t
Cisavi.CG.ENS81.R3.1347971-1357962.09077.t
Cisavi.CG.ENS81.R3.1347971-1357962.09078.t
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
13 results
| IPR Term | Analysis | Definition |
|---|---|---|
| MATH/TRAF_dom | SMART | MATH/TRAF domain |
| TRAF-like | Gene3D | TRAF-like |
| Znf_RING/FYVE/PHD | Gene3D | Zinc finger, RING/FYVE/PHD-type |
| Znf_RING_CS | ProSitePatterns | Zinc finger, RING-type, conserved site |
| Znf_TRAF | ProSiteProfiles | Zinc finger, TRAF-type |
| Znf_TRAF | Pfam | Zinc finger, TRAF-type |
| Znf_RING | SMART | Zinc finger, RING-type |
| TRAF4_MATH | CDD | TNF receptor-associated factor 4, MATH domain |
| Znf_RING | ProSiteProfiles | Zinc finger, RING-type |
| TRAF-like | SUPERFAMILY | TRAF-like |
| MATH/TRAF_dom | ProSiteProfiles | MATH/TRAF domain |
| TNF_rcpt--assoc_TRAF | PIRSF | TNF receptor-associated factor TRAF |
| TRAF4 | PANTHER | TNF receptor-associated factor 4 |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
26 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| DNA binding | Hs | molecular function |
| tumor necrosis factor receptor binding | Hs | molecular function |
| protein binding | Hs | molecular function |
| intracellular | Hs | cellular component |
| nucleus | Hs | cellular component |
| cytoplasm | Hs | cellular component |
| cytoskeleton | Hs | cellular component |
| plasma membrane | Hs | cellular component |
| bicellular tight junction | Hs | cellular component |
| apoptotic process | Hs | biological process |
| signal transduction | Hs | biological process |
| activation of NF-kappaB-inducing kinase activity | Hs | biological process |
| multicellular organism development | Hs | biological process |
| zinc ion binding | Hs | molecular function |
| membrane | Hs | cellular component |
| protein kinase binding | Hs | molecular function |
| cell junction | Hs | cellular component |
| ubiquitin protein ligase binding | Hs | molecular function |
| thioesterase binding | Hs | molecular function |
| identical protein binding | Hs | molecular function |
| regulation of apoptotic process | Hs | biological process |
| positive regulation of protein kinase activity | Hs | biological process |
| positive regulation of JNK cascade | Hs | biological process |
| metal ion binding | Hs | molecular function |
| perinuclear region of cytoplasm | Hs | cellular component |
| WW domain binding | Hs | molecular function |
GO (Blast)
42 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| ubiquitin ligase complex | Hs | cellular component | 184 | 1.63e-52 |
| DNA binding | Hs | molecular function | 544 | 0.0 |
| ubiquitin-protein transferase activity | Hs | molecular function | 184 | 1.63e-52 |
| signal transducer activity | Hs | molecular function | 184 | 1.63e-52 |
| receptor binding | Hs | molecular function | 184 | 1.63e-52 |
| tumor necrosis factor receptor binding | Hs | molecular function | 544 | 0.0 |
| CD40 receptor binding | Hs | molecular function | 184 | 1.63e-52 |
| protein binding | Hs | molecular function | 544 | 0.0 |
| intracellular | Hs | cellular component | 544 | 0.0 |
| nucleus | Hs | cellular component | 544 | 0.0 |
| nucleoplasm | Hs | cellular component | 184 | 1.63e-52 |
| cytoplasm | Hs | cellular component | 544 | 0.0 |
| mitochondrion | Hs | cellular component | 171 | 4.81e-47 |
| endosome | Hs | cellular component | 171 | 4.81e-47 |
| cytosol | Hs | cellular component | 184 | 1.63e-52 |
| cytoskeleton | Hs | cellular component | 544 | 0.0 |
| plasma membrane | Hs | cellular component | 544 | 0.0 |
| bicellular tight junction | Hs | cellular component | 544 | 0.0 |
| cell cortex | Hs | cellular component | 184 | 1.63e-52 |
| zinc ion binding | Hs | molecular function | 544 | 0.0 |
| lipid binding | Hs | molecular function | 184 | 1.63e-52 |
| cytoplasmic side of plasma membrane | Hs | cellular component | 184 | 1.63e-52 |
| vesicle membrane | Hs | cellular component | 184 | 1.63e-52 |
| membrane | Hs | cellular component | 544 | 0.0 |
| transferase activity | Hs | molecular function | 184 | 1.63e-52 |
| enzyme binding | Hs | molecular function | 184 | 1.63e-52 |
| protein kinase binding | Hs | molecular function | 544 | 0.0 |
| protein phosphatase binding | Hs | molecular function | 184 | 1.63e-52 |
| cell junction | Hs | cellular component | 544 | 0.0 |
| mitogen-activated protein kinase kinase kinase binding | Hs | molecular function | 184 | 1.63e-52 |
| ubiquitin protein ligase binding | Hs | molecular function | 544 | 0.0 |
| thioesterase binding | Hs | molecular function | 544 | 0.0 |
| CD40 receptor complex | Hs | cellular component | 184 | 1.63e-52 |
| identical protein binding | Hs | molecular function | 544 | 0.0 |
| membrane raft | Hs | cellular component | 184 | 1.63e-52 |
| sphingolipid binding | Hs | molecular function | 184 | 1.63e-52 |
| metal ion binding | Hs | molecular function | 544 | 0.0 |
| perinuclear region of cytoplasm | Hs | cellular component | 544 | 0.0 |
| WW domain binding | Hs | molecular function | 544 | 0.0 |
| TRAF2-GSTP1 complex | Hs | cellular component | 184 | 1.63e-52 |
| AIP1-IRE1 complex | Hs | cellular component | 184 | 1.63e-52 |
| IRE1-TRAF2-ASK1 complex | Hs | cellular component | 184 | 1.63e-52 |
GO (InterProScan)
6 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein binding | Gene3D | molecular function | 3.0E-63 |
| signal transduction | PIRSF | biological process | 9.8E-69 |
| activation of NF-kappaB-inducing kinase activity | CDD | biological process | 1.74288E-107 |
| zinc ion binding | PIRSF | molecular function | 9.8E-69 |
| regulation of apoptotic process | PIRSF | biological process | 9.8E-69 |
| positive regulation of JNK cascade | CDD | biological process | 1.74288E-107 |
