Gene Card
Best human hits
LRP1; LRP2; SORL1
Unique Gene ID
Cirobu.g00016244
Gene Model ID
NCBI:KH.108950252
Location
KhL154:249235..251929
Transcript Models and Sequences
n/a
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Click here to see the tree inference method
InterPro
5 results
| IPR Term | Analysis | Definition |
|---|---|---|
| LDrepeatLR_classA_rpt | ProSiteProfiles | Low-density lipoprotein (LDL) receptor class A repeat |
| LDrepeatLR_classA_rpt | CDD | Low-density lipoprotein (LDL) receptor class A repeat |
| LDL_receptor-like_sf | SUPERFAMILY | LDL receptor-like superfamily |
| LDrepeatLR_classA_rpt | SMART | Low-density lipoprotein (LDL) receptor class A repeat |
| LDrepeatLR_classA_rpt | PRINTS | Low-density lipoprotein (LDL) receptor class A repeat |
GOSlim
52 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| Golgi membrane | Blast | cellular component |
| RNA binding | Blast | molecular function |
| transmembrane signaling receptor activity | Blast | molecular function |
| calcium ion binding | Blast | molecular function |
| protein binding | Blast | molecular function |
| extracellular region | Blast | cellular component |
| extracellular space | Blast | cellular component |
| nucleus | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| lysosome | Blast | cellular component |
| lysosomal membrane | Blast | cellular component |
| endosome | Blast | cellular component |
| early endosome | Blast | cellular component |
| endoplasmic reticulum | Blast | cellular component |
| Golgi apparatus | Blast | cellular component |
| plasma membrane | Blast | cellular component |
| integral component of plasma membrane | Blast | cellular component |
| brush border | Blast | cellular component |
| focal adhesion | Blast | cellular component |
| membrane | Blast | cellular component |
| integral component of membrane | Blast | cellular component |
| basolateral plasma membrane | Blast | cellular component |
| apical plasma membrane | Blast | cellular component |
| axon | Blast | cellular component |
| brush border membrane | Blast | cellular component |
| cell projection | Blast | cellular component |
| neuronal cell body | Blast | cellular component |
| macromolecular complex binding | Blast | molecular function |
| apical part of cell | Blast | cellular component |
| metal ion binding | Blast | molecular function |
| membrane organization | Blast | biological process |
| extracellular exosome | Blast | cellular component |
| binding | Blast | molecular function |
| enzyme binding | Blast | molecular function |
| organelle organization | Blast | biological process |
| nuclear envelope | Blast | cellular component |
| intracellular organelle lumen | Blast | cellular component |
| Golgi apparatus part | Blast | cellular component |
| membrane part | Blast | cellular component |
| endomembrane system | Blast | cellular component |
| plasma membrane part | Blast | cellular component |
| cell surface | Blast | cellular component |
| intracellular organelle part | Blast | cellular component |
| whole membrane | Blast | cellular component |
| bounding membrane of organelle | Blast | cellular component |
| cytoplasmic vesicle | Blast | cellular component |
| macromolecular complex | Blast | cellular component |
| receptor binding | Blast | molecular function |
| transcription factor binding | Blast | molecular function |
| protein transport | Blast | biological process |
| anion binding | Blast | molecular function |
| carbohydrate derivative binding | Blast | molecular function |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
65 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| Golgi membrane | Hs | cellular component | 87.0 | 1.27e-17 |
| amyloid-beta binding | Hs | molecular function | 87.0 | 1.27e-17 |
| protease binding | Hs | molecular function | 80.1 | 2.35e-15 |
| RNA binding | Hs | molecular function | 80.1 | 2.35e-15 |
| receptor activity | Hs | molecular function | 80.1 | 2.35e-15 |
| transmembrane signaling receptor activity | Hs | molecular function | 87.0 | 1.27e-17 |
| low-density lipoprotein receptor activity | Hs | molecular function | 87.0 | 1.27e-17 |
| scavenger receptor activity | Hs | molecular function | 80.1 | 2.35e-15 |
| calcium ion binding | Hs | molecular function | 80.1 | 2.35e-15 |
| protein binding | Hs | molecular function | 87.0 | 1.27e-17 |
| extracellular region | Hs | cellular component | 87.0 | 1.27e-17 |
| extracellular space | Hs | cellular component | 87.0 | 1.27e-17 |
| nucleus | Hs | cellular component | 80.1 | 2.35e-15 |
| nuclear envelope lumen | Hs | cellular component | 87.0 | 1.27e-17 |
| cytoplasm | Hs | cellular component | 80.1 | 2.35e-15 |
| lysosome | Hs | cellular component | 79.3 | 3.58e-15 |
| lysosomal membrane | Hs | cellular component | 80.1 | 2.35e-15 |
| endosome | Hs | cellular component | 87.0 | 1.27e-17 |
| early endosome | Hs | cellular component | 87.0 | 1.27e-17 |
| endoplasmic reticulum | Hs | cellular component | 87.0 | 1.27e-17 |
| Golgi apparatus | Hs | cellular component | 87.0 | 1.27e-17 |
| trans-Golgi network | Hs | cellular component | 87.0 | 1.27e-17 |
| plasma membrane | Hs | cellular component | 80.1 | 2.35e-15 |
| integral component of plasma membrane | Hs | cellular component | 87.0 | 1.27e-17 |
| brush border | Hs | cellular component | 79.3 | 3.58e-15 |
| clathrin-coated pit | Hs | cellular component | 80.1 | 2.35e-15 |
| focal adhesion | Hs | cellular component | 80.1 | 2.35e-15 |
| drug binding | Hs | molecular function | 79.3 | 3.58e-15 |
| external side of plasma membrane | Hs | cellular component | 79.3 | 3.58e-15 |
| endosome membrane | Hs | cellular component | 87.0 | 1.27e-17 |
| membrane | Hs | cellular component | 87.0 | 1.27e-17 |
| integral component of membrane | Hs | cellular component | 87.0 | 1.27e-17 |
| basolateral plasma membrane | Hs | cellular component | 80.1 | 2.35e-15 |
| apical plasma membrane | Hs | cellular component | 79.3 | 3.58e-15 |
| alpha-2 macroglobulin receptor activity | Hs | molecular function | 80.1 | 2.35e-15 |
| SH3 domain binding | Hs | molecular function | 79.3 | 3.58e-15 |
| clathrin-coated vesicle | Hs | cellular component | 80.1 | 2.35e-15 |
| endocytic vesicle | Hs | cellular component | 79.3 | 3.58e-15 |
| low-density lipoprotein particle binding | Hs | molecular function | 87.0 | 1.27e-17 |
| apolipoprotein receptor activity | Hs | molecular function | 80.1 | 2.35e-15 |
| ADP-ribosylation factor binding | Hs | molecular function | 87.0 | 1.27e-17 |
| axon | Hs | cellular component | 79.3 | 3.58e-15 |
| dendrite | Hs | cellular component | 80.1 | 2.35e-15 |
| clathrin-coated vesicle membrane | Hs | cellular component | 79.3 | 3.58e-15 |
| endocytic vesicle membrane | Hs | cellular component | 80.1 | 2.35e-15 |
| brush border membrane | Hs | cellular component | 79.3 | 3.58e-15 |
| endosome lumen | Hs | cellular component | 79.3 | 3.58e-15 |
| Golgi cisterna | Hs | cellular component | 87.0 | 1.27e-17 |
| clathrin heavy chain binding | Hs | molecular function | 80.1 | 2.35e-15 |
| apolipoprotein binding | Hs | molecular function | 80.1 | 2.35e-15 |
| low-density lipoprotein particle | Hs | cellular component | 87.0 | 1.27e-17 |
| steroid hormone receptor binding | Hs | molecular function | 79.3 | 3.58e-15 |
| lipoprotein transporter activity | Hs | molecular function | 80.1 | 2.35e-15 |
| cell projection | Hs | cellular component | 79.3 | 3.58e-15 |
| neuronal cell body | Hs | cellular component | 80.1 | 2.35e-15 |
| receptor complex | Hs | cellular component | 80.1 | 2.35e-15 |
| heparan sulfate proteoglycan binding | Hs | molecular function | 80.1 | 2.35e-15 |
| macromolecular complex binding | Hs | molecular function | 80.1 | 2.35e-15 |
| apical part of cell | Hs | cellular component | 79.3 | 3.58e-15 |
| metal ion binding | Hs | molecular function | 80.1 | 2.35e-15 |
| chaperone binding | Hs | molecular function | 79.3 | 3.58e-15 |
| recycling endosome | Hs | cellular component | 87.0 | 1.27e-17 |
| extracellular exosome | Hs | cellular component | 87.0 | 1.27e-17 |
| lipoprotein particle receptor binding | Hs | molecular function | 80.1 | 2.35e-15 |
| plasma membrane protein complex | Hs | cellular component | 80.1 | 2.35e-15 |
GO (InterProScan)
1 result
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein binding | PRINTS | molecular function | 2.0E-25 |
