Gene Card
Best human hits
MAPKAPK2; MAPKAPK3; MAPKAPK5
Unique Gene ID
Cirobu.g00014597
Gene Model ID
KH2012:KH.S497.9
Location
KhS497:12582..23485
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000008202 |
NCBI Reference Sequence | XM_002128020.2 |
cien92669
Plate: VES84_B20
cien129311
Plate: VES90_O12
cieg014j09
Plate: R1CiGC17j13
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Prot_kinase_dom | SMART | Protein kinase domain |
Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
MAPKAPK_C | Gene3D | MAP kinase activated protein kinase, C-terminal |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Prot_kinase_dom | Pfam | Protein kinase domain |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
protein kinase activity | Orthology | molecular function |
protein serine/threonine kinase activity | Orthology | molecular function |
signal transducer activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
calmodulin binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
centrosome | Orthology | cellular component |
cytosol | Orthology | cellular component |
protein phosphorylation | Orthology | biological process |
cellular response to DNA damage stimulus | Orthology | biological process |
signal transduction | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
transferase activity | Orthology | molecular function |
response to lipopolysaccharide | Orthology | biological process |
response to cytokine | Orthology | biological process |
protein autophosphorylation | Orthology | biological process |
extracellular exosome | Orthology | cellular component |
intracellular signal transduction | Orthology | biological process |
positive regulation of catalytic activity | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
innate immune response | Orthology | biological process |
cellular metabolic process | Orthology | biological process |
organic substance metabolic process | Orthology | biological process |
defense response | Orthology | biological process |
small GTPase mediated signal transduction | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
cellular response to stress | Orthology | biological process |
mRNA catabolic process | Orthology | biological process |
membrane organization | Orthology | biological process |
organelle organization | Orthology | biological process |
positive regulation of gene expression | Orthology | biological process |
animal organ development | Orthology | biological process |
protein kinase binding | Orthology | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
MAPK cascade | Hs | biological process |
nucleotide binding | Hs | molecular function |
activation of MAPK activity | Hs | biological process |
toll-like receptor signaling pathway | Hs | biological process |
protein kinase activity | Hs | molecular function |
protein serine/threonine kinase activity | Hs | molecular function |
calmodulin-dependent protein kinase activity | Hs | molecular function |
MAP kinase kinase activity | Hs | molecular function |
signal transducer activity | Hs | molecular function |
protein binding | Hs | molecular function |
calmodulin binding | Hs | molecular function |
ATP binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
cytoplasm | Hs | cellular component |
centrosome | Hs | cellular component |
cytosol | Hs | cellular component |
protein phosphorylation | Hs | biological process |
leukotriene metabolic process | Hs | biological process |
inflammatory response | Hs | biological process |
cellular response to DNA damage stimulus | Hs | biological process |
signal transduction | Hs | biological process |
cell surface receptor signaling pathway | Hs | biological process |
Ras protein signal transduction | Hs | biological process |
calcium-dependent protein serine/threonine kinase activity | Hs | molecular function |
kinase activity | Hs | molecular function |
phosphorylation | Hs | biological process |
transferase activity | Hs | molecular function |
peptidyl-serine phosphorylation | Hs | biological process |
response to lipopolysaccharide | Hs | biological process |
response to cytokine | Hs | biological process |
cellular response to vascular endothelial growth factor stimulus | Hs | biological process |
p38MAPK cascade | Hs | biological process |
regulation of mRNA stability | Hs | biological process |
macropinocytosis | Hs | biological process |
protein autophosphorylation | Hs | biological process |
vascular endothelial growth factor receptor signaling pathway | Hs | biological process |
mRNA stabilization | Hs | biological process |
inner ear development | Hs | biological process |
mitogen-activated protein kinase binding | Hs | molecular function |
extracellular exosome | Hs | cellular component |
3'-UTR-mediated mRNA stabilization | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 498 | 8.04e-178 |
p53 binding | Hs | molecular function | 266 | 2.29e-85 |
protein kinase activity | Hs | molecular function | 498 | 8.04e-178 |
protein serine/threonine kinase activity | Hs | molecular function | 498 | 8.04e-178 |
calmodulin-dependent protein kinase activity | Hs | molecular function | 498 | 8.04e-178 |
MAP kinase kinase activity | Hs | molecular function | 498 | 8.04e-178 |
signal transducer activity | Hs | molecular function | 479 | 2.64e-170 |
protein binding | Hs | molecular function | 498 | 8.04e-178 |
calmodulin binding | Hs | molecular function | 498 | 8.04e-178 |
ATP binding | Hs | molecular function | 498 | 8.04e-178 |
nucleus | Hs | cellular component | 498 | 8.04e-178 |
nucleoplasm | Hs | cellular component | 498 | 8.04e-178 |
cytoplasm | Hs | cellular component | 498 | 8.04e-178 |
centrosome | Hs | cellular component | 479 | 2.64e-170 |
cytosol | Hs | cellular component | 498 | 8.04e-178 |
calcium-dependent protein serine/threonine kinase activity | Hs | molecular function | 498 | 8.04e-178 |
kinase activity | Hs | molecular function | 498 | 8.04e-178 |
transferase activity | Hs | molecular function | 498 | 8.04e-178 |
mitogen-activated protein kinase binding | Hs | molecular function | 498 | 8.04e-178 |
extracellular exosome | Hs | cellular component | 479 | 2.64e-170 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | SMART | molecular function | 5.8E-90 |
ATP binding | SMART | molecular function | 5.8E-90 |
protein phosphorylation | SMART | biological process | 5.8E-90 |