Aniseed - Gene card

Gene Card

Best human hits

TRAF3; TRAF5; TRAF6

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00014422

Gene Model ID

KH2012:KH.S396.6

Location

KhS396:13190..22662

Transcript Models and Sequences

KH2012:KH.S396.6.v1.A.SL1-1
KH2012:KH.S396.6.v1.A.SL2-1

External Database Gene Card

External database links

2 results

Database	Gene ID
ENSEMBL	ENSCING00000020502
NCBI Reference Sequence	NM_001078511.1

Collections

Gateway full ORF

2 results

cien136039

Plate: VES91_J15

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term	Analysis	Definition
TNF_rcpt--assoc_TRAF	PIRSF	TNF receptor-associated factor TRAF
TRAF-like	SUPERFAMILY	TRAF-like
MATH/TRAF_dom	SMART	MATH/TRAF domain
TRAF6_MATH	CDD	TNF receptor-associated factor 6, MATH domain
Znf_RING/FYVE/PHD	Gene3D	Zinc finger, RING/FYVE/PHD-type
Znf_TRAF	Pfam	Zinc finger, TRAF-type
TRAF-like	Gene3D	TRAF-like
MATH/TRAF_dom	ProSiteProfiles	MATH/TRAF domain
Znf_RING_CS	ProSitePatterns	Zinc finger, RING-type, conserved site
Znf_RING	SMART	Zinc finger, RING-type
Znf_TRAF	ProSiteProfiles	Zinc finger, TRAF-type
Znf_RING	ProSiteProfiles	Zinc finger, RING-type

GOSlim

65 results

GO Term	Annotation Origin	Type
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
protein polyubiquitination	Orthology	biological process
immune system process	Orthology	biological process
ubiquitin-protein transferase activity	Orthology	molecular function
signal transducer activity	Blast	molecular function
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
cytoplasm	Orthology	cellular component
mitochondrion	Blast	cellular component
endosome	Orthology	cellular component
centrosome	Blast	cellular component
cytosol	Orthology	cellular component
plasma membrane	Orthology	cellular component
immune response	Orthology	biological process
cellular response to DNA damage stimulus	Orthology	biological process
signal transduction	Orthology	biological process
zinc ion binding	Orthology	molecular function
protein ubiquitination	Orthology	biological process
transferase activity	Orthology	molecular function
cytokine-mediated signaling pathway	Orthology	biological process
protein kinase binding	Orthology	molecular function
ubiquitin protein ligase binding	Orthology	molecular function
macromolecular complex	Orthology	cellular component
identical protein binding	Orthology	molecular function
regulation of apoptotic process	Orthology	biological process
positive regulation of apoptotic process	Orthology	biological process
negative regulation of apoptotic process	Orthology	biological process
innate immune response	Orthology	biological process
negative regulation of transcription, DNA-templated	Orthology	biological process
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
metal ion binding	Orthology	molecular function
protein N-terminus binding	Orthology	molecular function
cell development	Orthology	biological process
perinuclear region of cytoplasm	Orthology	cellular component
positive regulation of catalytic activity	Orthology	biological process
intracellular signal transduction	Orthology	biological process
protein serine/threonine kinase activity	Orthology	molecular function
positive regulation of signal transduction	Orthology	biological process
anatomical structure formation involved in morphogenesis	Orthology	biological process
nervous system development	Orthology	biological process
receptor binding	Orthology	molecular function
intracellular non-membrane-bounded organelle	Orthology	cellular component
cell periphery	Orthology	cellular component
cytoplasmic part	Orthology	cellular component
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
enzyme regulator activity	Orthology	molecular function
protein kinase activity	Orthology	molecular function
cellular response to stress	Orthology	biological process
protein phosphorylation	Orthology	biological process
animal organ development	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
plasma membrane part	Orthology	cellular component
intracellular organelle part	Orthology	cellular component
whole membrane	Orthology	cellular component
bounding membrane of organelle	Orthology	cellular component
peptidase activity, acting on L-amino acid peptides	Orthology	molecular function
cell differentiation	Orthology	biological process
proteolysis	Orthology	biological process
enzyme binding	Orthology	molecular function
integral component of plasma membrane	Orthology	cellular component
cell surface receptor signaling pathway	Orthology	biological process
regulation of signal transduction	Orthology	biological process
protein metabolic process	Orthology	biological process
response to lipopolysaccharide	Orthology	biological process
cellular response to organic substance	Orthology	biological process

GO (Orthology)

73 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
activation of MAPK activity	Hs	biological process
protein polyubiquitination	Hs	biological process
ossification	Hs	biological process
neural tube closure	Hs	biological process
toll-like receptor signaling pathway	Hs	biological process
immune system process	Hs	biological process
MyD88-dependent toll-like receptor signaling pathway	Hs	biological process
ubiquitin-protein transferase activity	Hs	molecular function
tumor necrosis factor receptor binding	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
lipid droplet	Hs	cellular component
cytosol	Hs	cellular component
plasma membrane	Hs	cellular component
cell cortex	Hs	cellular component
immune response	Hs	biological process
cellular response to DNA damage stimulus	Hs	biological process
signal transduction	Hs	biological process
I-kappaB kinase/NF-kappaB signaling	Hs	biological process
activation of NF-kappaB-inducing kinase activity	Hs	biological process
JNK cascade	Hs	biological process
zinc ion binding	Hs	molecular function
animal organ morphogenesis	Hs	biological process
cytoplasmic side of plasma membrane	Hs	cellular component
endosome membrane	Hs	cellular component
protein ubiquitination	Hs	biological process
protein deubiquitination	Hs	biological process
transferase activity	Hs	molecular function
cytokine-mediated signaling pathway	Hs	biological process
antigen processing and presentation of exogenous peptide antigen via MHC class II	Hs	biological process
protein kinase binding	Hs	molecular function
osteoclast differentiation	Hs	biological process
membrane protein intracellular domain proteolysis	Hs	biological process
positive regulation of protein ubiquitination	Hs	biological process
mitogen-activated protein kinase kinase kinase binding	Hs	molecular function
ubiquitin conjugating enzyme binding	Hs	molecular function
ubiquitin protein ligase binding	Hs	molecular function
thioesterase binding	Hs	molecular function
activation of protein kinase activity	Hs	biological process
macromolecular complex	Hs	cellular component
toll-like receptor 9 signaling pathway	Hs	biological process
CD40 receptor complex	Hs	cellular component
Fc-epsilon receptor signaling pathway	Hs	biological process
T-helper 1 type immune response	Hs	biological process
identical protein binding	Hs	molecular function
histone deacetylase binding	Hs	molecular function
regulation of apoptotic process	Hs	biological process
myeloid dendritic cell differentiation	Hs	biological process
positive regulation of apoptotic process	Hs	biological process
negative regulation of apoptotic process	Hs	biological process
regulation of I-kappaB kinase/NF-kappaB signaling	Hs	biological process
positive regulation of I-kappaB kinase/NF-kappaB signaling	Hs	biological process
protein kinase B binding	Hs	molecular function
positive regulation of JUN kinase activity	Hs	biological process
positive regulation of interleukin-6 biosynthetic process	Hs	biological process
bone resorption	Hs	biological process
negative regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
bone remodeling	Hs	biological process
metal ion binding	Hs	molecular function
protein N-terminus binding	Hs	molecular function
cell development	Hs	biological process
perinuclear region of cytoplasm	Hs	cellular component
T cell receptor signaling pathway	Hs	biological process
positive regulation of sequence-specific DNA binding transcription factor activity	Hs	biological process
positive regulation of NF-kappaB transcription factor activity	Hs	biological process
protein autoubiquitination	Hs	biological process
ubiquitin protein ligase activity	Hs	molecular function
interleukin-1-mediated signaling pathway	Hs	biological process
protein K63-linked ubiquitination	Hs	biological process
cellular response to lipopolysaccharide	Hs	biological process

GO (Blast)

32 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
ubiquitin-protein transferase activity	Hs	molecular function	246	2.56e-74
signal transducer activity	Hs	molecular function	214	5.55e-62
tumor necrosis factor receptor binding	Hs	molecular function	246	2.56e-74
protein binding	Hs	molecular function	246	2.56e-74
nucleus	Hs	cellular component	246	2.56e-74
cytoplasm	Hs	cellular component	246	2.56e-74
mitochondrion	Hs	cellular component	214	5.55e-62
endosome	Hs	cellular component	214	5.55e-62
lipid droplet	Hs	cellular component	246	2.56e-74
centrosome	Hs	cellular component	209	2.48e-60
cytosol	Hs	cellular component	246	2.56e-74
plasma membrane	Hs	cellular component	246	2.56e-74
cell cortex	Hs	cellular component	246	2.56e-74
zinc ion binding	Hs	molecular function	246	2.56e-74
cytoplasmic side of plasma membrane	Hs	cellular component	246	2.56e-74
endosome membrane	Hs	cellular component	246	2.56e-74
transferase activity	Hs	molecular function	246	2.56e-74
protein kinase binding	Hs	molecular function	246	2.56e-74
protein phosphatase binding	Hs	molecular function	214	5.55e-62
mitogen-activated protein kinase kinase kinase binding	Hs	molecular function	246	2.56e-74
ubiquitin conjugating enzyme binding	Hs	molecular function	246	2.56e-74
ubiquitin protein ligase binding	Hs	molecular function	246	2.56e-74
thioesterase binding	Hs	molecular function	246	2.56e-74
macromolecular complex	Hs	cellular component	246	2.56e-74
CD40 receptor complex	Hs	cellular component	246	2.56e-74
identical protein binding	Hs	molecular function	246	2.56e-74
histone deacetylase binding	Hs	molecular function	246	2.56e-74
protein kinase B binding	Hs	molecular function	246	2.56e-74
metal ion binding	Hs	molecular function	246	2.56e-74
protein N-terminus binding	Hs	molecular function	246	2.56e-74
perinuclear region of cytoplasm	Hs	cellular component	246	2.56e-74
ubiquitin protein ligase activity	Hs	molecular function	246	2.56e-74

GO (InterProScan)

8 results

GO Term	Analysis	Type	e-value
ubiquitin-protein transferase activity	CDD	molecular function	5.2052E-82
tumor necrosis factor receptor binding	CDD	molecular function	5.2052E-82
protein binding	Gene3D	molecular function	1.0E-56
signal transduction	PIRSF	biological process	1.5E-116
zinc ion binding	PIRSF	molecular function	1.5E-116
protein ubiquitination	CDD	biological process	5.2052E-82
regulation of apoptotic process	PIRSF	biological process	1.5E-116
regulation of I-kappaB kinase/NF-kappaB signaling	CDD	biological process	5.2052E-82