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Gene Card

Best human hits

IRF4; IRF8; IRF9

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00013859

Gene Model ID

KH2012:KH.S1404.2

Location

KhS1404:1184..4060

Transcript Models and Sequences

  KH2012:KH.S1404.2.v1.A.ND2-1
KH2012:KH.S1404.2.v1.A.SL1-1

External Database Gene Card

External database links

3 results

Database Gene ID
ENSEMBL ENSCING00000000808
NCBI Reference Sequence NM_001078274.1
NCBI Reference Sequence XM_018816624.1
Collections

Gateway full ORF

2 results

cima830985

Plate: VES61_B24

cima889719

Plate: VES70_K13

Gene collection 1 (N. Satoh)

1 result

cilv026j10

Plate: R1CiGC27e16

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

8 results

IPR Term Analysis Definition
WH-like_DNA-bd_sf Gene3D Winged helix-like DNA-binding domain superfamily
Interferon_reg_fact_DNA-bd_dom SMART Interferon regulatory factor DNA-binding domain
Interferon_reg_fact_DNA-bd_dom PRINTS Interferon regulatory factor DNA-binding domain
Interferon_reg_fact_DNA-bd_dom PANTHER Interferon regulatory factor DNA-binding domain
Interferon_reg_fact_DNA-bd_dom CDD Interferon regulatory factor DNA-binding domain
Interferon_reg_fact_DNA-bd_dom ProSiteProfiles Interferon regulatory factor DNA-binding domain
WH_DNA-bd_sf SUPERFAMILY Winged helix DNA-binding domain superfamily
Interferon_reg_fact_DNA-bd_dom Pfam Interferon regulatory factor DNA-binding domain

GOSlim

62 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
RNA polymerase II regulatory region sequence-specific DNA binding Orthology molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Orthology molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
DNA binding Orthology molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
transcription from RNA polymerase II promoter Orthology biological process
immune response Orthology biological process
cell surface receptor signaling pathway Orthology biological process
transcription factor binding Orthology molecular function
response to bacterium Orthology biological process
membrane Orthology cellular component
cytokine-mediated signaling pathway Orthology biological process
sequence-specific DNA binding Orthology molecular function
transcription regulatory region DNA binding Orthology molecular function
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Orthology molecular function
immune system process Orthology biological process
transcription cofactor activity Orthology molecular function
apoptotic process Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
negative regulation of cell proliferation Orthology biological process
cell junction Orthology cellular component
cell differentiation Orthology biological process
response to lipopolysaccharide Orthology biological process
identical protein binding Orthology molecular function
protein homodimerization activity Orthology molecular function
positive regulation of apoptotic process Orthology biological process
innate immune response Orthology biological process
cell development Orthology biological process
extracellular exosome Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
nuclear lumen Orthology cellular component
macromolecular complex Orthology cellular component
cellular protein modification process Orthology biological process
transferase activity Orthology molecular function
animal organ development Orthology biological process
negative regulation of signal transduction Orthology biological process
cellular process Orthology biological process
defense response Orthology biological process
organelle organization Orthology biological process
transcription initiation from RNA polymerase II promoter Orthology biological process
cellular response to organic substance Orthology biological process
intracellular organelle part Orthology cellular component
whole membrane Orthology cellular component
endosome Orthology cellular component
bounding membrane of organelle Orthology cellular component
response to molecule of bacterial origin Orthology biological process
signal transduction Orthology biological process
intracellular signal transduction Orthology biological process
positive regulation of signal transduction Orthology biological process
response to organic substance Orthology biological process
protein transport Orthology biological process

GO (Orthology)

83 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
nuclear nucleosome Hs cellular component
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
core promoter binding Hs molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
DNA binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
regulation of transcription from RNA polymerase II promoter Hs biological process
transcription from RNA polymerase II promoter Hs biological process
protein methylation Hs biological process
phagocytosis Hs biological process
immune response Hs biological process
cell surface receptor signaling pathway Hs biological process
transcription factor binding Hs molecular function
response to bacterium Hs biological process
membrane Hs cellular component
protein-lysine N-methyltransferase activity Hs molecular function
peptidyl-lysine methylation Hs biological process
cytokine-mediated signaling pathway Hs biological process
myeloid cell differentiation Hs biological process
negative regulation of toll-like receptor signaling pathway Hs biological process
T cell activation Hs biological process
defense response to bacterium Hs biological process
defense response to protozoan Hs biological process
myeloid dendritic cell differentiation Hs biological process
positive regulation of DNA binding Hs biological process
sequence-specific DNA binding Hs molecular function
histone H3 acetylation Hs biological process
histone H4 acetylation Hs biological process
negative regulation of growth of symbiont in host Hs biological process
transcription regulatory region DNA binding Hs molecular function
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
defense response to virus Hs biological process
positive regulation of transcription initiation from RNA polymerase II promoter Hs biological process
cellular response to lipopolysaccharide Hs biological process
cellular response to interferon-gamma Hs biological process
T-helper 17 cell lineage commitment Hs biological process
RNA polymerase II core promoter sequence-specific DNA binding Hs molecular function
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
immune system process Hs biological process
transcription cofactor activity Hs molecular function
apoptotic process Hs biological process
cellular response to DNA damage stimulus Hs biological process
cell cycle arrest Hs biological process
negative regulation of cell proliferation Hs biological process
response to virus Hs biological process
endosome membrane Hs cellular component
viral process Hs biological process
immunoglobulin mediated immune response Hs biological process
protein domain specific binding Hs molecular function
cell junction Hs cellular component
cell differentiation Hs biological process
keratinocyte differentiation Hs biological process
lipopolysaccharide-mediated signaling pathway Hs biological process
negative regulation of type I interferon production Hs biological process
positive regulation of type I interferon production Hs biological process
response to peptidoglycan Hs biological process
response to lipopolysaccharide Hs biological process
TRIF-dependent toll-like receptor signaling pathway Hs biological process
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
positive regulation of apoptotic process Hs biological process
positive regulation of I-kappaB kinase/NF-kappaB signaling Hs biological process
response to exogenous dsRNA Hs biological process
skin development Hs biological process
innate immune response Hs biological process
cell development Hs biological process
positive regulation of cytokine secretion Hs biological process
regulation of immune response Hs biological process
extracellular exosome Hs cellular component

GO (Blast)

20 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nuclear nucleosome Hs cellular component 169 5.32e-47
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function 161 4.67e-44
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function 169 5.32e-47
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 169 5.32e-47
core promoter binding Hs molecular function 151 9.74e-41
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 169 5.32e-47
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 161 4.67e-44
DNA binding Hs molecular function 169 5.32e-47
transcription factor activity, sequence-specific DNA binding Hs molecular function 169 5.32e-47
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function 161 4.67e-44
protein binding Hs molecular function 169 5.32e-47
nucleus Hs cellular component 169 5.32e-47
nucleoplasm Hs cellular component 169 5.32e-47
cytoplasm Hs cellular component 161 4.67e-44
cytosol Hs cellular component 169 5.32e-47
transcription factor binding Hs molecular function 169 5.32e-47
membrane Hs cellular component 169 5.32e-47
protein-lysine N-methyltransferase activity Hs molecular function 169 5.32e-47
sequence-specific DNA binding Hs molecular function 169 5.32e-47
transcription regulatory region DNA binding Hs molecular function 169 5.32e-47

GO (InterProScan)

1 result

GO Term Analysis Type e-value
transcription regulatory region DNA binding PANTHER molecular function 1.3E-85

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