Aniseed - Gene card

Gene Card

Best human hits

IQGAP1; IQGAP2; IQGAP3

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00013174

Gene Model ID

KH2012:KH.L87.13

Location

KhL87:315411..348968

Transcript Models and Sequences

KH2012:KH.L87.13.v1.A.SL3-1
KH2012:KH.L87.13.v2.A.SL2-1
KH2012:KH.L87.13.v2.A.SL4-1
KH2012:KH.L87.13.v2.A.SL5-1
KH2012:KH.L87.13.v3.A.SL2-1
KH2012:KH.L87.13.v3.A.SL4-1
KH2012:KH.L87.13.v3.A.SL5-1
KH2012:KH.L87.13.v4.A.SL3-1
KH2012:KH.L87.13.v5.A.SL1-1
KH2012:KH.L87.13.v6.A.SL1-1

External Database Gene Card

External database links

7 results

Database	Gene ID
ENSEMBL	ENSCING00000000781
ENSEMBL	ENSCING00000023905
NCBI Reference Sequence	NM_001032456.1
NCBI Reference Sequence	XM_009863551.2
NCBI Reference Sequence	XM_018816273.1
NCBI Reference Sequence	XM_018816274.1
NCBI Reference Sequence	XM_018816276.1

Collections

Gateway full ORF

2 results

Gene collection 1 (N. Satoh)

2 results

cieg058o04

Plate: R1CiGC24l18

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

You can Right Mouse Click on internal nodes, leaves and outside the tree to see multiple options adapted to your selection.
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

Click here to see how you can interact with this tree
Click here to see the tree inference method

Gene Annotations

InterPro

19 results

IPR Term	Analysis	Definition
IQ_motif_EF-hand-BS	ProSiteProfiles	IQ motif, EF-hand binding site
RasGAP_CS	ProSitePatterns	Ras GTPase-activating protein, conserved site
WW_dom	CDD	WW domain
RasGAP_dom	Pfam	Ras GTPase-activating domain
Rho_GTPase_activation_prot	SUPERFAMILY	Rho GTPase activation protein
RasGAP_C	Pfam	RasGAP protein, C-terminal
IQ_motif_EF-hand-BS	SMART	IQ motif, EF-hand binding site
WW_dom_sf	SUPERFAMILY	WW domain superfamily
WW_dom	ProSiteProfiles	WW domain
IQ_motif_EF-hand-BS	Pfam	IQ motif, EF-hand binding site
RasGAP_dom	ProSiteProfiles	Ras GTPase-activating domain
RasGAP_dom	SMART	Ras GTPase-activating domain
WW_dom	ProSitePatterns	WW domain
CH_dom_sf	SUPERFAMILY	CH domain superfamily
CH_dom_sf	Gene3D	CH domain superfamily
CH-domain	ProSiteProfiles	Calponin homology domain
CH-domain	SMART	Calponin homology domain
CH-domain	CDD	Calponin homology domain
CH-domain	Pfam	Calponin homology domain

GOSlim

70 results

GO Term	Annotation Origin	Type
G1/S transition of mitotic cell cycle	Orthology	biological process
actin binding	Orthology	molecular function
GTPase activator activity	Orthology	molecular function
calcium ion binding	Orthology	molecular function
protein binding	Orthology	molecular function
calmodulin binding	Orthology	molecular function
nucleus	Orthology	cellular component
cytoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
microtubule	Orthology	cellular component
plasma membrane	Orthology	cellular component
focal adhesion	Orthology	cellular component
signal transduction	Orthology	biological process
cell surface	Orthology	cellular component
positive regulation of gene expression	Orthology	biological process
negative regulation of gene expression	Orthology	biological process
microtubule cytoskeleton	Orthology	cellular component
membrane	Orthology	cellular component
protein kinase binding	Orthology	molecular function
lamellipodium	Orthology	cellular component
axon	Orthology	cellular component
midbody	Orthology	cellular component
cell leading edge	Orthology	cellular component
neuron projection	Orthology	cellular component
regulation of GTPase activity	Orthology	biological process
positive regulation of GTPase activity	Orthology	biological process
membrane raft	Orthology	cellular component
actin filament binding	Orthology	molecular function
extracellular exosome	Orthology	cellular component
cellular response to organic substance	Orthology	biological process
positive regulation of catalytic activity	Orthology	biological process
intracellular signal transduction	Orthology	biological process
protein serine/threonine kinase activity	Orthology	molecular function
positive regulation of signal transduction	Orthology	biological process
cell projection	Orthology	cellular component
plasma membrane region	Orthology	cellular component
protein phosphorylation	Orthology	biological process
GTPase regulator activity	Orthology	molecular function
anion binding	Orthology	molecular function
cytoskeletal part	Orthology	cellular component
cell junction	Orthology	cellular component
cell surface receptor signaling pathway	Orthology	biological process
small GTPase mediated signal transduction	Orthology	biological process
cellular component organization	Orthology	biological process
cytoskeleton	Orthology	cellular component
plasma membrane part	Orthology	cellular component
enzyme binding	Orthology	molecular function
cell projection part	Orthology	cellular component
intracellular organelle part	Orthology	cellular component
whole membrane	Orthology	cellular component
cytoplasmic vesicle	Orthology	cellular component
endomembrane system	Orthology	cellular component
bounding membrane of organelle	Orthology	cellular component
intracellular part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
organelle organization	Orthology	biological process
cytoplasmic part	Orthology	cellular component
intracellular non-membrane-bounded organelle	Orthology	cellular component
enzyme activator activity	Orthology	molecular function
cell adhesion molecule binding	Orthology	molecular function
protein kinase activity	Orthology	molecular function
cell adhesion	Orthology	biological process
G-protein coupled receptor signaling pathway	Orthology	biological process
cytoskeletal protein binding	Orthology	molecular function
macromolecular complex binding	Orthology	molecular function
cell development	Orthology	biological process
animal organ development	Orthology	biological process
neuron projection development	Orthology	biological process
cellular protein localization	Orthology	biological process
neuron projection morphogenesis	Orthology	biological process

GO (Orthology)

78 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
G1/S transition of mitotic cell cycle	Hs	biological process
activation of MAPK activity	Hs	biological process
ruffle	Hs	cellular component
regulation of cytokine production	Hs	biological process
positive regulation of protein phosphorylation	Hs	biological process
actin binding	Hs	molecular function
GTPase inhibitor activity	Hs	molecular function
GTPase activator activity	Hs	molecular function
calcium ion binding	Hs	molecular function
protein binding	Hs	molecular function
calmodulin binding	Hs	molecular function
phosphatidylinositol-3,4,5-trisphosphate binding	Hs	molecular function
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
microtubule	Hs	cellular component
actin filament	Hs	cellular component
plasma membrane	Hs	cellular component
microvillus	Hs	cellular component
cell-cell junction	Hs	cellular component
focal adhesion	Hs	cellular component
signal transduction	Hs	biological process
epidermal growth factor receptor signaling pathway	Hs	biological process
Ras protein signal transduction	Hs	biological process
regulation of mitotic cell cycle	Hs	biological process
regulation of cell size	Hs	biological process
fibroblast growth factor receptor signaling pathway	Hs	biological process
cell surface	Hs	cellular component
positive regulation of gene expression	Hs	biological process
negative regulation of gene expression	Hs	biological process
actin cytoskeleton	Hs	cellular component
microtubule cytoskeleton	Hs	cellular component
membrane	Hs	cellular component
lateral plasma membrane	Hs	cellular component
Ras GTPase binding	Hs	molecular function
Rho GTPase binding	Hs	molecular function
protein kinase binding	Hs	molecular function
protein phosphatase binding	Hs	molecular function
protein domain specific binding	Hs	molecular function
lamellipodium	Hs	cellular component
filopodium	Hs	cellular component
axon	Hs	cellular component
growth cone	Hs	cellular component
midbody	Hs	cellular component
intracellular ribonucleoprotein complex	Hs	cellular component
secretory granule membrane	Hs	cellular component
extrinsic component of cytoplasmic side of plasma membrane	Hs	cellular component
cell leading edge	Hs	cellular component
filamentous actin	Hs	cellular component
negative regulation of GTPase activity	Hs	biological process
Arp2/3 complex-mediated actin nucleation	Hs	biological process
slit diaphragm	Hs	cellular component
cytoplasmic ribonucleoprotein granule	Hs	cellular component
neuron projection	Hs	cellular component
regulation of GTPase activity	Hs	biological process
positive regulation of MAP kinase activity	Hs	biological process
protein serine/threonine kinase activator activity	Hs	molecular function
positive regulation of GTPase activity	Hs	biological process
S100 protein binding	Hs	molecular function
membrane raft	Hs	cellular component
cadherin binding	Hs	molecular function
positive regulation of protein kinase activity	Hs	biological process
platelet-derived growth factor receptor signaling pathway	Hs	biological process
Rac GTPase binding	Hs	molecular function
actin filament binding	Hs	molecular function
mitogen-activated protein kinase binding	Hs	molecular function
positive regulation of focal adhesion assembly	Hs	biological process
extracellular exosome	Hs	cellular component
thrombin-activated receptor signaling pathway	Hs	biological process
myosin VI light chain binding	Hs	molecular function
cellular response to calcium ion	Hs	biological process
cellular response to organic substance	Hs	biological process
cellular response to epidermal growth factor stimulus	Hs	biological process
Arp2/3 complex binding	Hs	molecular function
glomerular visceral epithelial cell development	Hs	biological process
positive regulation of dendrite development	Hs	biological process
positive regulation of cellular protein localization	Hs	biological process
neuron projection extension	Hs	biological process

GO (Blast)

50 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score
ruffle	Hs	cellular component	1655
actin binding	Hs	molecular function	1112
GTPase inhibitor activity	Hs	molecular function	1655
GTPase activator activity	Hs	molecular function	1655
calcium ion binding	Hs	molecular function	1655
protein binding	Hs	molecular function	1655
calmodulin binding	Hs	molecular function	1655
phosphatidylinositol-3,4,5-trisphosphate binding	Hs	molecular function	1655
nucleus	Hs	cellular component	1655
cytoplasm	Hs	cellular component	1655
cytosol	Hs	cellular component	1655
microtubule	Hs	cellular component	1655
actin filament	Hs	cellular component	1655
plasma membrane	Hs	cellular component	1655
microvillus	Hs	cellular component	1112
cell-cell junction	Hs	cellular component	1655
focal adhesion	Hs	cellular component	1655
cell surface	Hs	cellular component	1112
actin cytoskeleton	Hs	cellular component	1655
microtubule cytoskeleton	Hs	cellular component	1655
membrane	Hs	cellular component	1655
lateral plasma membrane	Hs	cellular component	1655
Ras GTPase binding	Hs	molecular function	1419
Rho GTPase binding	Hs	molecular function	1655
protein kinase binding	Hs	molecular function	1655
protein phosphatase binding	Hs	molecular function	1655
protein domain specific binding	Hs	molecular function	1655
lamellipodium	Hs	cellular component	1112
filopodium	Hs	cellular component	1112
axon	Hs	cellular component	1655
growth cone	Hs	cellular component	1655
midbody	Hs	cellular component	1655
intracellular ribonucleoprotein complex	Hs	cellular component	1655
secretory granule membrane	Hs	cellular component	1655
extrinsic component of cytoplasmic side of plasma membrane	Hs	cellular component	1655
cell leading edge	Hs	cellular component	1655
filamentous actin	Hs	cellular component	1112
slit diaphragm	Hs	cellular component	1655
cytoplasmic ribonucleoprotein granule	Hs	cellular component	1655
neuron projection	Hs	cellular component	1655
protein serine/threonine kinase activator activity	Hs	molecular function	1655
S100 protein binding	Hs	molecular function	1655
membrane raft	Hs	cellular component	1655
cadherin binding	Hs	molecular function	1655
Rac GTPase binding	Hs	molecular function	1655
actin filament binding	Hs	molecular function	1112
mitogen-activated protein kinase binding	Hs	molecular function	1655
extracellular exosome	Hs	cellular component	1655
myosin VI light chain binding	Hs	molecular function	1419
Arp2/3 complex binding	Hs	molecular function	1112

GO (InterProScan)

3 results

GO Term	Analysis	Type	e-value
protein binding	Pfam	molecular function	1.5E-34
signal transduction	SUPERFAMILY	biological process	1.06E-70
regulation of GTPase activity	SMART	biological process	1.3E-65