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GENE CARD

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Gene Card

Best human hits

AC006486.1; GSK3A; GSK3B

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00012943

Gene Model ID

KH2012:KH.L65.6

Location

KhL65:212475..215152

Transcript Models and Sequences

  KH2012:KH.L65.6.v1.A.SL1-1
KH2012:KH.L65.6.v1.A.SL2-1
KH2012:KH.L65.6.v1.A.SL3-1

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000001821
NCBI Reference Sequence NM_001032425.1
Collections

Gateway full ORF

2 results

cien34869

Plate: VES75_C21

cien174601

Plate: VES97_J06

Gene collection 1 (N. Satoh)

1 result

cilv006n05

Plate: R1CiGC25b21

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term Analysis Definition
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Prot_kinase_dom SMART Protein kinase domain
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Prot_kinase_dom Pfam Protein kinase domain

GOSlim

55 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
protein kinase activity Orthology molecular function
protein serine/threonine kinase activity Orthology molecular function
receptor binding Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
nucleus Blast cellular component
nucleoplasm Blast cellular component
cytoplasm Orthology cellular component
mitochondrion Orthology cellular component
centrosome Blast cellular component
cytosol Orthology cellular component
microtubule Orthology cellular component
plasma membrane Blast cellular component
protein phosphorylation Orthology biological process
nervous system development Orthology biological process
negative regulation of signal transduction Orthology biological process
positive regulation of gene expression Orthology biological process
membrane Blast cellular component
kinase activity Orthology molecular function
phosphorylation Orthology biological process
cell migration Orthology biological process
transferase activity Orthology molecular function
protein kinase binding Orthology molecular function
ubiquitin protein ligase binding Blast molecular function
intracellular signal transduction Orthology biological process
neuronal cell body Orthology cellular component
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
negative regulation of canonical Wnt signaling pathway Orthology biological process
postsynapse Orthology cellular component
organic substance metabolic process Orthology biological process
oxidation-reduction process Orthology biological process
nucleobase-containing compound metabolic process Orthology biological process
regulation of gene expression Orthology biological process
G-protein coupled receptor signaling pathway Orthology biological process
developmental process Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cellular response to organic substance Orthology biological process
cell-cell signaling Orthology biological process
cytoplasmic part Orthology cellular component
macromolecular complex Orthology cellular component
protein ubiquitination Orthology biological process
proteolysis Orthology biological process
positive regulation of apoptotic process Orthology biological process
DNA metabolic process Orthology biological process
protein metabolic process Orthology biological process
chemical synaptic transmission Orthology biological process
nervous system process Orthology biological process
apoptotic process Orthology biological process
organelle organization Orthology biological process
regulation of cellular metabolic process Orthology biological process
transcription factor binding Blast molecular function
enzyme binding Blast molecular function
cytoskeletal protein binding Blast molecular function
plasma membrane part Blast cellular component

GO (Orthology)

54 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
nucleotide binding Hs molecular function
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
receptor binding Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
cytoplasm Hs cellular component
mitochondrion Hs cellular component
cytosol Hs cellular component
microtubule Hs cellular component
carbohydrate metabolic process Hs biological process
glycogen metabolic process Hs biological process
regulation of gene expression by genetic imprinting Hs biological process
protein phosphorylation Hs biological process
dopamine receptor signaling pathway Hs biological process
nervous system development Hs biological process
aging Hs biological process
insulin receptor signaling pathway Hs biological process
negative regulation of signal transduction Hs biological process
positive regulation of gene expression Hs biological process
positive regulation of peptidyl-threonine phosphorylation Hs biological process
Wnt signaling pathway Hs biological process
kinase activity Hs molecular function
phosphorylation Hs biological process
cell migration Hs biological process
transferase activity Hs molecular function
peptidyl-serine phosphorylation Hs biological process
peptidyl-threonine phosphorylation Hs biological process
protein kinase binding Hs molecular function
beta-catenin destruction complex Hs cellular component
positive regulation of protein ubiquitination Hs biological process
negative regulation of TOR signaling Hs biological process
positive regulation of proteasomal ubiquitin-dependent protein catabolic process Hs biological process
cellular response to insulin stimulus Hs biological process
positive regulation of peptidyl-serine phosphorylation Hs biological process
protein kinase A catalytic subunit binding Hs molecular function
neuronal cell body Hs cellular component
proteasome-mediated ubiquitin-dependent protein catabolic process Hs biological process
positive regulation of neuron apoptotic process Hs biological process
hypermethylation of CpG island Hs biological process
positive regulation of protein catabolic process Hs biological process
positive regulation of heart contraction Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
negative regulation of insulin receptor signaling pathway Hs biological process
tau-protein kinase activity Hs molecular function
excitatory postsynaptic potential Hs biological process
cellular response to organic cyclic compound Hs biological process
negative regulation of canonical Wnt signaling pathway Hs biological process
extrinsic apoptotic signaling pathway Hs biological process
extrinsic apoptotic signaling pathway in absence of ligand Hs biological process
apical dendrite Hs cellular component
postsynapse Hs cellular component
regulation of autophagy of mitochondrion Hs biological process
proximal dendrite Hs cellular component

GO (Blast)

33 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 659 0.0
RNA polymerase II transcription factor binding Hs molecular function 659 0.0
protease binding Hs molecular function 659 0.0
p53 binding Hs molecular function 659 0.0
protein kinase activity Hs molecular function 659 0.0
protein serine/threonine kinase activity Hs molecular function 659 0.0
receptor binding Hs molecular function 639 0.0
protein binding Hs molecular function 659 0.0
ATP binding Hs molecular function 659 0.0
nucleus Hs cellular component 659 0.0
nucleoplasm Hs cellular component 659 0.0
cytoplasm Hs cellular component 659 0.0
mitochondrion Hs cellular component 659 0.0
centrosome Hs cellular component 659 0.0
cytosol Hs cellular component 659 0.0
microtubule Hs cellular component 639 0.0
plasma membrane Hs cellular component 659 0.0
beta-catenin binding Hs molecular function 659 0.0
membrane Hs cellular component 659 0.0
kinase activity Hs molecular function 659 0.0
transferase activity Hs molecular function 659 0.0
protein kinase binding Hs molecular function 659 0.0
beta-catenin destruction complex Hs cellular component 659 0.0
ubiquitin protein ligase binding Hs molecular function 659 0.0
protein kinase A catalytic subunit binding Hs molecular function 659 0.0
dynactin binding Hs molecular function 659 0.0
neuronal cell body Hs cellular component 639 0.0
tau-protein kinase activity Hs molecular function 659 0.0
NF-kappaB binding Hs molecular function 659 0.0
apical dendrite Hs cellular component 639 0.0
postsynapse Hs cellular component 659 0.0
proximal dendrite Hs cellular component 639 0.0
Wnt signalosome Hs cellular component 659 0.0

GO (InterProScan)

3 results

GO Term Analysis Type e-value
protein kinase activity SMART molecular function 2.8E-84
ATP binding SMART molecular function 2.8E-84
protein phosphorylation SMART biological process 2.8E-84

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