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GENE CARD

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Gene Card

Best human hits

FOXC1; FOXC2; FOXL1

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00012813

Gene Model ID

KH2012:KH.L57.25

Location

KhL57:98135..106045

Transcript Models and Sequences

  KH2012:KH.L57.25.v1.A.SL1-1

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000020724
NCBI Reference Sequence NM_001078240.1
Collections

Gene collection 1 (N. Satoh)

1 result

cilv050a24

Plate: R1CiGC44e14

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

4 results

Gene Phylogeny

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Gene Annotations

InterPro

9 results

IPR Term Analysis Definition
Fork_head_dom CDD Fork head domain
Fork_head_dom ProSiteProfiles Fork head domain
WH-like_DNA-bd_sf Gene3D Winged helix-like DNA-binding domain superfamily
Fork_head_dom PRINTS Fork head domain
WH_DNA-bd_sf SUPERFAMILY Winged helix DNA-binding domain superfamily
TF_fork_head_CS_2 ProSitePatterns Fork head domain conserved site 2
Fork_head_dom Pfam Fork head domain
Fork_head_dom SMART Fork head domain
TF_fork_head_CS_1 ProSitePatterns Fork head domain conserved site1

GOSlim

55 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
RNA polymerase II regulatory region sequence-specific DNA binding Orthology molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Orthology molecular function
angiogenesis Orthology biological process
blood vessel development Orthology biological process
DNA binding Orthology molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcription coactivator activity Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytosol Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
transcription from RNA polymerase II promoter Orthology biological process
Notch signaling pathway Orthology biological process
multicellular organism development Orthology biological process
brain development Orthology biological process
heart development Orthology biological process
transcription factor binding Orthology molecular function
cell proliferation Orthology biological process
anatomical structure morphogenesis Orthology biological process
positive regulation of gene expression Orthology biological process
cell migration Orthology biological process
nuclear body Orthology cellular component
cell differentiation Orthology biological process
identical protein binding Orthology molecular function
sequence-specific DNA binding Orthology molecular function
transcription regulatory region DNA binding Orthology molecular function
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding Orthology molecular function
negative regulation of transcription, DNA-templated Orthology biological process
system development Orthology biological process
reproductive process Orthology biological process
animal organ development Orthology biological process
anatomical structure formation involved in morphogenesis Orthology biological process
vasculature development Orthology biological process
intracellular non-membrane-bounded organelle Orthology cellular component
nuclear lumen Orthology cellular component
anatomical structure development Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cellular response to organic substance Orthology biological process
gamete generation Orthology biological process
response to organic substance Orthology biological process
cell development Orthology biological process
extracellular matrix organization Orthology biological process
chromatin binding Orthology molecular function
cell adhesion Orthology biological process
developmental process Orthology biological process
blood vessel morphogenesis Orthology biological process
cytokine-mediated signaling pathway Orthology biological process
regulation of molecular function Orthology biological process
nervous system process Orthology biological process

GO (Orthology)

87 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
transcription coactivator binding Hs molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
skeletal system development Hs biological process
ossification Hs biological process
angiogenesis Hs biological process
ovarian follicle development Hs biological process
blood vessel development Hs biological process
branching involved in blood vessel morphogenesis Hs biological process
eye development Hs biological process
ureteric bud development Hs biological process
somitogenesis Hs biological process
kidney development Hs biological process
lymph vessel development Hs biological process
lymphangiogenesis Hs biological process
endochondral ossification Hs biological process
heart morphogenesis Hs biological process
DNA binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function
transcription coactivator activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
nuclear heterochromatin Hs cellular component
cytosol Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
transcription from RNA polymerase II promoter Hs biological process
Notch signaling pathway Hs biological process
multicellular organism development Hs biological process
brain development Hs biological process
mesoderm development Hs biological process
heart development Hs biological process
transcription factor binding Hs molecular function
cell proliferation Hs biological process
insulin receptor signaling pathway Hs biological process
DNA binding, bending Hs molecular function
germ cell migration Hs biological process
anatomical structure morphogenesis Hs biological process
response to hormone Hs biological process
positive regulation of gene expression Hs biological process
positive regulation of epithelial to mesenchymal transition Hs biological process
neural crest cell development Hs biological process
cell migration Hs biological process
negative regulation of angiogenesis Hs biological process
nuclear body Hs cellular component
cerebellum development Hs biological process
cell differentiation Hs biological process
collagen fibril organization Hs biological process
glycosaminoglycan metabolic process Hs biological process
chromatin DNA binding Hs molecular function
positive regulation of cell adhesion mediated by integrin Hs biological process
embryonic heart tube development Hs biological process
vascular endothelial growth factor signaling pathway Hs biological process
identical protein binding Hs molecular function
camera-type eye development Hs biological process
positive regulation of DNA binding Hs biological process
sequence-specific DNA binding Hs molecular function
transcription regulatory region DNA binding Hs molecular function
positive regulation of transcription, DNA-templated Hs biological process
negative regulation of mitotic cell cycle Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
regulation of organ growth Hs biological process
vascular endothelial growth factor receptor signaling pathway Hs biological process
paraxial mesoderm formation Hs biological process
embryonic cranial skeleton morphogenesis Hs biological process
embryonic viscerocranium morphogenesis Hs biological process
artery morphogenesis Hs biological process
regulation of blood vessel size Hs biological process
ventricular cardiac muscle tissue morphogenesis Hs biological process
cardiac muscle cell proliferation Hs biological process
chemokine-mediated signaling pathway Hs biological process
cellular response to epidermal growth factor stimulus Hs biological process
glomerular visceral epithelial cell differentiation Hs biological process
positive regulation of cell migration involved in sprouting angiogenesis Hs biological process
promoter-specific chromatin binding Hs molecular function
cellular response to chemokine Hs biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
positive regulation of multicellular organism growth Hs biological process
negative regulation of sequence-specific DNA binding transcription factor activity Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
neuromuscular process controlling balance Hs biological process

GO (Blast)

22 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function 207 4.62e-61
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 209 5.74e-62
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 209 5.74e-62
transcription coactivator binding Hs molecular function 207 4.62e-61
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function 207 4.62e-61
DNA binding Hs molecular function 209 5.74e-62
transcription factor activity, sequence-specific DNA binding Hs molecular function 209 5.74e-62
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function 209 5.74e-62
transcription coactivator activity Hs molecular function 207 4.62e-61
protein binding Hs molecular function 209 5.74e-62
nucleus Hs cellular component 209 5.74e-62
nucleoplasm Hs cellular component 209 5.74e-62
nuclear heterochromatin Hs cellular component 207 4.62e-61
cytosol Hs cellular component 207 4.62e-61
transcription factor binding Hs molecular function 207 4.62e-61
DNA binding, bending Hs molecular function 207 4.62e-61
nuclear body Hs cellular component 209 5.74e-62
chromatin DNA binding Hs molecular function 209 5.74e-62
identical protein binding Hs molecular function 209 5.74e-62
sequence-specific DNA binding Hs molecular function 209 5.74e-62
transcription regulatory region DNA binding Hs molecular function 209 5.74e-62
promoter-specific chromatin binding Hs molecular function 209 5.74e-62

GO (InterProScan)

3 results

GO Term Analysis Type e-value
transcription factor activity, sequence-specific DNA binding SMART molecular function 4.2E-64
regulation of transcription, DNA-templated SMART biological process 4.2E-64
sequence-specific DNA binding SMART molecular function 4.2E-64

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