Gene Card
Best human hits
PIAS1; PIAS2; PIAS3
Unique Gene ID
Cirobu.g00012760
Gene Model ID
KH2012:KH.L53.1
Location
KhL53:28296..39307
Transcript Models and Sequences
KH2012:KH.L53.1.v1.A.ND2-1
KH2012:KH.L53.1.v1.A.SL1-1
KH2012:KH.L53.1.v1.A.SL3-1
KH2012:KH.L53.1.v1.A.SL4-1
KH2012:KH.L53.1.v2.A.SL1-1
KH2012:KH.L53.1.v2.A.SL3-1
KH2012:KH.L53.1.v3.A.SL1-1
KH2012:KH.L53.1.v3.A.SL3-1
KH2012:KH.L53.1.v4.A.SL1-1
KH2012:KH.L53.1.v4.A.SL3-1
cien132570
Plate: VES91_B02
cien143618
Plate: VES92_B17
cieg056b13
Plate: R1CiGC24d11
n/a
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IPR Term | Analysis | Definition |
---|---|---|
PIAS2 | PANTHER | E3 SUMO-protein ligase PIAS2 |
Znf_RING/FYVE/PHD | Gene3D | Zinc finger, RING/FYVE/PHD-type |
PINIT | ProSiteProfiles | PINIT domain |
PINIT_sf | Gene3D | PINIT domain superfamily |
Znf_MIZ | Pfam | Zinc finger, MIZ-type |
Znf_MIZ | ProSiteProfiles | Zinc finger, MIZ-type |
PINIT | Pfam | PINIT domain |
SAP_dom | SMART | SAP domain |
SAP_dom | ProSiteProfiles | SAP domain |
SAP_dom_sf | SUPERFAMILY | SAP domain superfamily |
SAP_dom_sf | Gene3D | SAP domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
G1/S transition of mitotic cell cycle | Orthology | biological process |
negative regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
DNA binding | Orthology | molecular function |
transcription coactivator activity | Orthology | molecular function |
transcription corepressor activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
transcription, DNA-templated | Orthology | biological process |
regulation of transcription, DNA-templated | Orthology | biological process |
regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
spermatogenesis | Orthology | biological process |
protein C-terminus binding | Orthology | molecular function |
transcription factor binding | Orthology | molecular function |
zinc ion binding | Orthology | molecular function |
positive regulation of gene expression | Orthology | biological process |
nuclear body | Orthology | cellular component |
nuclear speck | Orthology | cellular component |
transferase activity | Orthology | molecular function |
enzyme binding | Orthology | molecular function |
ubiquitin protein ligase binding | Orthology | molecular function |
regulation of cell proliferation | Orthology | biological process |
negative regulation of apoptotic process | Orthology | biological process |
synapse | Orthology | cellular component |
positive regulation of transcription, DNA-templated | Orthology | biological process |
positive regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
metal ion binding | Orthology | molecular function |
protein N-terminus binding | Orthology | molecular function |
regulation of molecular function | Orthology | biological process |
negative regulation of transcription, DNA-templated | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
nervous system process | Orthology | biological process |
response to organic substance | Orthology | biological process |
metal ion transport | Orthology | biological process |
molecular function regulator | Orthology | molecular function |
transmembrane transport | Orthology | biological process |
monovalent inorganic cation transport | Orthology | biological process |
protein modification by small protein conjugation | Orthology | biological process |
ubiquitin-like protein transferase activity | Orthology | molecular function |
signal transduction | Orthology | biological process |
response to lipid | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
proteolysis | Orthology | biological process |
cell differentiation | Orthology | biological process |
receptor binding | Orthology | molecular function |
cytokine-mediated signaling pathway | Orthology | biological process |
regulation of signal transduction | Orthology | biological process |
innate immune response | Orthology | biological process |
DNA repair | Orthology | biological process |
cell-cell signaling | Orthology | biological process |
nuclear lumen | Orthology | cellular component |
transcription factor activity, sequence-specific DNA binding | Orthology | molecular function |
intracellular signal transduction | Orthology | biological process |
cellular response to DNA damage stimulus | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
positive regulation of apoptotic process | Orthology | biological process |
macromolecular complex | Orthology | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
DNA binding | Hs | molecular function | 327 | 4.34e-103 |
transcription coactivator activity | Hs | molecular function | 327 | 4.34e-103 |
transcription corepressor activity | Hs | molecular function | 310 | 3.87e-96 |
protein binding | Hs | molecular function | 328 | 1.51e-103 |
nucleus | Hs | cellular component | 328 | 1.51e-103 |
nucleoplasm | Hs | cellular component | 328 | 1.51e-103 |
cytoplasm | Hs | cellular component | 328 | 1.51e-103 |
protein C-terminus binding | Hs | molecular function | 328 | 1.51e-103 |
transcription factor binding | Hs | molecular function | 327 | 4.34e-103 |
zinc ion binding | Hs | molecular function | 328 | 1.51e-103 |
potassium channel regulator activity | Hs | molecular function | 328 | 1.51e-103 |
nuclear body | Hs | cellular component | 327 | 4.34e-103 |
PML body | Hs | cellular component | 327 | 4.34e-103 |
nuclear speck | Hs | cellular component | 328 | 1.51e-103 |
transferase activity | Hs | molecular function | 328 | 1.51e-103 |
SUMO transferase activity | Hs | molecular function | 328 | 1.51e-103 |
enzyme binding | Hs | molecular function | 328 | 1.51e-103 |
protein domain specific binding | Hs | molecular function | 310 | 3.87e-96 |
dendrite | Hs | cellular component | 328 | 1.51e-103 |
ubiquitin protein ligase binding | Hs | molecular function | 327 | 4.34e-103 |
synapse | Hs | cellular component | 328 | 1.51e-103 |
metal ion binding | Hs | molecular function | 328 | 1.51e-103 |
protein N-terminus binding | Hs | molecular function | 328 | 1.51e-103 |
androgen receptor binding | Hs | molecular function | 327 | 4.34e-103 |
SUMO ligase activity | Hs | molecular function | 327 | 4.34e-103 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
zinc ion binding | Pfam | molecular function | 7.1E-22 |
SUMO transferase activity | PANTHER | molecular function | 1.7E-107 |