Gene Card
Best human hits
CFL1; CFL2; DSTN
Unique Gene ID
Cirobu.g00012396
Gene Model ID
KH2012:KH.L37.33
Location
KhL37:306454..307836
Transcript Models and Sequences
KH2012:KH.L37.33.v1.A.nonSL2-1
KH2012:KH.L37.33.v1.A.SL1-1
KH2012:KH.L37.33.v1.A.SL3-1
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000023268 |
NCBI Reference Sequence | XM_002131318.3 |
cima863872
Plate: VES65_M09
cima8100420
Plate: VES72_P19
cicl007o03
Plate: R1CiGC09o05
cicl016f08
Plate: R1CiGC10i02
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
ADF/Cofilin | PANTHER | ADF/Cofilin |
ADF-H | Pfam | Actin-depolymerising factor homology domain |
ADF-H | ProSiteProfiles | Actin-depolymerising factor homology domain |
ADF-H/Gelsolin-like_dom_sf | Gene3D | ADF-H/Gelsolin-like domain superfamily |
ADF-H | SMART | Actin-depolymerising factor homology domain |
GO Term | Annotation Origin | Type |
---|---|---|
actin binding | Orthology | molecular function |
receptor binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
extracellular space | Orthology | cellular component |
intracellular | Orthology | cellular component |
nucleus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
cytoskeleton | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
focal adhesion | Orthology | cellular component |
protein phosphorylation | Orthology | biological process |
membrane | Orthology | cellular component |
lamellipodium | Orthology | cellular component |
vesicle | Orthology | cellular component |
cell projection | Orthology | cellular component |
negative regulation of apoptotic process | Orthology | biological process |
actin filament binding | Orthology | molecular function |
extracellular exosome | Orthology | cellular component |
membrane organization | Orthology | biological process |
cell division | Orthology | biological process |
cell migration | Orthology | biological process |
cell development | Orthology | biological process |
animal organ development | Orthology | biological process |
cell junction | Orthology | cellular component |
organelle organization | Orthology | biological process |
small GTPase mediated signal transduction | Orthology | biological process |
nuclear lumen | Orthology | cellular component |
cell morphogenesis | Orthology | biological process |
cellular process | Orthology | biological process |
organelle part | Orthology | cellular component |
cytoplasmic part | Orthology | cellular component |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
cell periphery | Orthology | cellular component |
cytoskeletal part | Orthology | cellular component |
cell projection membrane | Orthology | cellular component |
cell leading edge | Orthology | cellular component |
response to organic substance | Orthology | biological process |
cell | Orthology | cellular component |
cell morphogenesis involved in neuron differentiation | Orthology | biological process |
neuron projection morphogenesis | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
mitotic cytokinesis | Hs | biological process |
neural crest cell migration | Hs | biological process |
actin binding | Hs | molecular function |
receptor binding | Hs | molecular function |
protein binding | Hs | molecular function |
extracellular space | Hs | cellular component |
intracellular | Hs | cellular component |
nucleus | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
cytoskeleton | Hs | cellular component |
plasma membrane | Hs | cellular component |
cell-cell junction | Hs | cellular component |
focal adhesion | Hs | cellular component |
protein phosphorylation | Hs | biological process |
cytoskeleton organization | Hs | biological process |
actin filament organization | Hs | biological process |
Rho protein signal transduction | Hs | biological process |
skeletal muscle tissue development | Hs | biological process |
actin polymerization or depolymerization | Hs | biological process |
response to virus | Hs | biological process |
actin cytoskeleton | Hs | cellular component |
membrane | Hs | cellular component |
nuclear matrix | Hs | cellular component |
regulation of cell morphogenesis | Hs | biological process |
establishment of cell polarity | Hs | biological process |
Z disc | Hs | cellular component |
lamellipodium | Hs | cellular component |
actin cytoskeleton organization | Hs | biological process |
actin filament depolymerization | Hs | biological process |
positive regulation of actin filament depolymerization | Hs | biological process |
cortical actin cytoskeleton | Hs | cellular component |
lamellipodium membrane | Hs | cellular component |
I band | Hs | cellular component |
vesicle | Hs | cellular component |
ruffle membrane | Hs | cellular component |
cell projection | Hs | cellular component |
negative regulation of apoptotic process | Hs | biological process |
response to amino acid | Hs | biological process |
sarcomere organization | Hs | biological process |
muscle cell cellular homeostasis | Hs | biological process |
actin filament severing | Hs | biological process |
actin filament binding | Hs | molecular function |
regulation of dendritic spine morphogenesis | Hs | biological process |
extracellular exosome | Hs | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
actin binding | Hs | molecular function | 57.8 | 6.19e-11 |
receptor binding | Hs | molecular function | 55.1 | 8.51e-10 |
protein binding | Hs | molecular function | 57.8 | 6.19e-11 |
extracellular space | Hs | cellular component | 57.8 | 6.19e-11 |
intracellular | Hs | cellular component | 57.8 | 6.19e-11 |
nucleus | Hs | cellular component | 57.8 | 6.19e-11 |
cytoplasm | Hs | cellular component | 57.8 | 6.19e-11 |
cytosol | Hs | cellular component | 55.1 | 8.51e-10 |
cytoskeleton | Hs | cellular component | 57.8 | 6.19e-11 |
plasma membrane | Hs | cellular component | 55.1 | 8.51e-10 |
cell-cell junction | Hs | cellular component | 55.1 | 8.51e-10 |
focal adhesion | Hs | cellular component | 55.1 | 8.51e-10 |
actin cytoskeleton | Hs | cellular component | 57.8 | 6.19e-11 |
membrane | Hs | cellular component | 55.1 | 8.51e-10 |
nuclear matrix | Hs | cellular component | 57.8 | 6.19e-11 |
Z disc | Hs | cellular component | 57.8 | 6.19e-11 |
lamellipodium | Hs | cellular component | 55.1 | 8.51e-10 |
cortical actin cytoskeleton | Hs | cellular component | 55.1 | 5.65e-10 |
lamellipodium membrane | Hs | cellular component | 55.1 | 8.51e-10 |
I band | Hs | cellular component | 57.8 | 6.19e-11 |
vesicle | Hs | cellular component | 55.1 | 8.51e-10 |
ruffle membrane | Hs | cellular component | 55.1 | 8.51e-10 |
cell projection | Hs | cellular component | 55.1 | 8.51e-10 |
actin filament binding | Hs | molecular function | 57.8 | 6.19e-11 |
extracellular exosome | Hs | cellular component | 57.8 | 6.19e-11 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
actin binding | Pfam | molecular function | 6.1E-21 |
intracellular | Pfam | cellular component | 6.1E-21 |
actin cytoskeleton | PANTHER | cellular component | 3.2E-28 |
actin filament depolymerization | PANTHER | biological process | 3.2E-28 |